Structure of PDB 7o9m Chain t1 Binding Site BS01

Receptor Information
>7o9m Chain t1 (length=46) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EALAGAPLDNAPKEYPPKIQQLVQDIASLTLLEISDLNELLKKTLK
Ligand information
>7o9m Chain t4 (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PKIQQLVQDIASLTLLEISDLNELLKKTL
Receptor-Ligand Complex Structure
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PDB7o9m Structural basis for late maturation steps of the human mitoribosomal large subunit.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
A11 T14 L15 L16 I18
Binding residue
(residue number reindexed from 1)
A27 T30 L31 L32 I34
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006390 mitochondrial transcription
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:7o9m, PDBe:7o9m, PDBj:7o9m
PDBsum7o9m
PubMed34135318
UniProtP52815|RM12_HUMAN Large ribosomal subunit protein bL12m (Gene Name=MRPL12)

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