Structure of PDB 9c4g Chain t Binding Site BS01

Receptor Information
>9c4g Chain t (length=106) Species: 1747 (Cutibacterium acnes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKSLKIKKGDRVKVIAGNDKGAIGEVLSVDPARERVVVEGVNIRKHHGII
SSEAPIHVSNVQLVTKIDGKDVVTRVGYRRVDVTKRRPDGSEYAAQRSVR
YLKKEE
Ligand information
>9c4g Chain a (length=2903) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaaguuguguagugcgaucgguggaugccuuggcaccaagagccgauga
aggacguugugaccugcgauaagcccuggggaguuggugagcgagcugug
auccggggguguccgaauggggaaaccuggaauguccggaguaguguccg
guggcccugcccugaauguauaggggugugggugguaacgcggggaagug
aaacaucuuaguacccguaggaagagaaaacaagugugauuccgugagua
guggcgagcgaaagcggaggaggcuaaaccgugugugugucagguguugc
augugcgggguugugggggccuugugguucugcugccgcaggauuggcca
gugagaaauguugcgugaaggugaagcgucugggaaggcguaccggagug
ggugagaguccuguaacuguaagcguggcacuggugugggguugccccga
guagcgugggacucguggaauuucgcgugaaucuggcgggaccacccguc
aagccuaaauacuccuuggugaccgauaguggaugaguaccgugagggaa
gggugaaaaguaccccgggaggggagugaaagaguuccugaaaccggucg
caugcaagccgucagagccuguguggugauggcgugccuuuugaagaaug
agccugcgaguuagugaugcguggcgagguuaacccguggugggggaguc
guagcgaaagcgaguccgauaagggcgugagucgcguguucuagacccga
agcggugugaucuauccauggccaggaugaagcgucgguaagacgucgug
gagguccgaacccacuucaguugaaaauggaggggaugaguuguggauag
gggugaaaggccaaucaaacaccgugauagcugguucuccccgaaaugca
uuuaggugcagcguugcgugguucuuguuggagguagagcacuggauggu
cuagggggcuuaucggcuuaccgaaaucagccaaacuccgaaugcuggca
aguguagcguggcagugagacggcgggugauaagcuucgucgucgagagg
gaaacagcccagaucaucagcuaaggccccuaaguggugacucaguggga
aaggauguggaguugcguagacaaccaggagguuggcuuggaagcagcca
uccuugaaagagugcguaauagcucacuggucaagugauuccgcgccgau
aauguagcggggcuuaaguuauccgccgaagcuguggcaaccuguguggu
uggguaggggagcgucgugucaguggugaagcugccgggugacugugugg
uggaguugaugcgagugagaaugcaggcaugaguagcgugugacgggugg
gaaucccguccgccgauuauccaaggguuccagggucaaguuugucugcc
cugggugagucggguccuaaggcgaggccgacaggcguagucgaugggua
accaguugauauucugguaccggcuugucaccgcaagcugcggagggacg
cagugagguagcucauccccggugaugguuguccggggcuaagugugugg
acugucugguagguaaauccgcugggcgugaagguugaggcaugaugggg
agcccaugguugugggugagugagugauccuguacugucgagaaaagcuu
cgugagcgagguggcggguccgcccguacccuaaaccgacacugguggau
agguagaguauaccgaggcgaucgagugaaucguggugaaggaacucggc
aaaaugcccccguaacuuugggauaagggggaccugagcugucgugcacc
cgugcggugugguggcggugaggggcgcagaguccagggggaaacgacug
uuuaccaaaaacacagguccgugcgaagucguaagacgauguauacggac
ugacuccugcccggugcuggaagguuaaggggaacugugaguguaugcgu
agcggugaacuuaagccccaguaaacggcggugguaacuauaaccauccu
aagguagcgaaauuccuugucggguaaguuccgaccugcacgaauggagu
aacgauuucccuacugucuccaccaugaacucggugaaauugcauuacga
guaaagaugcucguuacgcgcagcaggacggaaagaccccgggaccuuua
cuauaguuugguauuggugauugggacgguuuucugauuguucugguuau
cucacuguggaccgugauccgguucaaggacagugccugauggguaguuu
gacuggggcggucgccuccuaaaggguaacggaggcgcccaaagguuccc
ucagccugguugguaaucagguggugaguguaagugcacaagggggcuug
acugugagacugacaggucgagcagggacgaaagucgggacuagugaucu
gacgguggcuuguggaugcgccgucacucaacggauaaaagguaccccgg
ggauaacaggcugaucuugcccgagcgcucauagcgacggcaugguuugg
caccucgaugucggcucgucgcauccuggggcuggagucggucccaaggg
uugggcuguucgcccauuaaagcggcacgcgagcuggguucagaacgucg
ugagacaguucggucccuauccgcugcgcgcggaggaaucuugagaaggg
cugucuuuaguacgagaggaccgagacggacugaccucuggugugccagu
uguucugccaagagcauggcugguuggcuacgucggguugugauaaccgc
ugaaagcaucuaagcgggaagcacgcuucaagauaaggguucccacagga
guguuccugguaagguccccgagagaugaucggguugauaggccagacgu
ggacgcaucguaagguguggagcugacugguacuaauagaccgaggacuu
uca
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>..<<<<.<<<<<.........>>>>>..>>>>>>...<<<<<<.....<
<....>>......>>>>>.>.........<<<..>>>..<<<<<<.....
<<.....>>....>>>>>>..<<<....<<<<..................
....>>>>......<<<<<<<<<......<<<<....>>>>.........
.........<<..<<<...<<<...<<<<<......>>>>>((......<
<<.....))>>>...>>>......>>>..>>......>>>>>..>>>>..
...<<<<<<<<.........>>>>>>>>.......<<<<..<<<<>>>>.
..>>>......]].>>>>>>>.]]...............<<....>>...
.]].........<<<<....>>>>..................>>>>>>>>
>>>.......<<<<..<<<.....>>>..>>>>...<.<........>.>
.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>....>>>>>>>>>>>>>..<<.<.
.<<<<<<<.....<<<<<<<<<..<<<....<<<.<<......>>.>>>.
....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>..
.<<<.....>>>......>>>>>>...>..>.>>..<<<<<<....<<<<
<....>>>>><<<<<<<<<....<<<<<<<<.....<<<...<<<.<<<<
...<<.<<<<....>>>>..>>...>>>>.>>>..>>.>.....>>>>>>
>>....>>>>>>>.>>..<<<<<<<<<........>>>>>>>>>....<<
<......>>>...<<<<.<<<...<<<(((.....<<<<<<.........
..<<..<<<<<<<<<........<<<<<.<<...<<<.........>>>.
..>>.........<<......>>...>>>>>....>>>>>>>>>.>>...
........)))......>>>>>>.>>>...>>>>>>><<<<<.....>>>
>>....>>>>>>..<<<<<<<<<.......<<<<<<<<....>>>.>>>>
>....>>>>>>>>>........>>>>>><......<<....<<<<<<...
....>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>
>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>...
<<<<<........>>>>>))<<<.<<..<..<....<<<<<<<<<....<
<<<..<<<..<<<<<.<<<<<<...((((...>>>>>><<..<<<<...<
<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>...>>>>...>>..
..<<.........>>.....>>>>>...>>>...>>>>.........>>>
>>>.>>>...>..>..>>.>>>>>>>..>>.....<<......>>>>>>>
.<<<<.....>>>>..>>>>..<<<<<...<<<<<<<<.<<.........
<.....<<<<<.....<..>......>>>>>.<<<..<<<<<<<.....<
......>.....>>>>>>>..>>>.............<<<<<<<<<..<<
<.........>>>..<<<<<<<.....<<<....>>>.......>>>>>>
>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<..<<....>>..
.>>>>>...>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>>>
..>>.>>>>>>>..>..>>.>>>>>>>>>>>>>>>.....>.((..<<<<
<......))>>>>>..<<<<<<<<.(((.[[......<<<<<<<<<<..<
<<<<.<<<.<<<<<.<<<<<<<<<<<<<<........>>>>>>>>>>>>>
>...<<.<<<<<<<.....>>>>>>>>>....>>>>>.>>>..>>>>>..
<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<<
...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>..
.<<<<..<<<<....>>>>..>>>>.<<<....>>>.>>)))]......<
<<<<<<.((..>>>>..))>>>>>>>.............>>>>..>>>>>
>.......<<<<.<.<.<<<<<..<<.......>>>..>>>>.>...>>>
>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>
.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<.
...>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..
<<<<<<<...............>>>>>>>.<<<<<...<<<<..<<<<<<
<<<<<<))))>>>>>>..>>>>>>..>>>>.>>>>>..<<<<....<<<<
<...........>>>>>....>>>>>>>>.......>>>>>>>..<<<<<
....>>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<..<<
....<<<<<....>>>>>...>>...>>>>>.>>>...>>>>......>>
>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9c4g Mechanistic basis for the translation inhibition of Cutibacterium acnes by Clindamycin.
Resolution2.53 Å
Binding residue
(original residue number in PDB)
M1 K2 S3 K5 K7 K8 G17 N18 V29 P31 H47 S73 N74 Q76 R89 Y92 R94 K99 R100 R101 R111 S112 K117
Binding residue
(residue number reindexed from 1)
M1 K2 S3 K5 K7 K8 G17 N18 V29 P31 H47 S59 N60 Q62 R75 Y78 R80 K85 R86 R87 R97 S98 K103
External links
PDB RCSB:9c4g, PDBe:9c4g, PDBj:9c4g
PDBsum9c4g
PubMed39122144
UniProtQ6A6N7|RL24_CUTAK Large ribosomal subunit protein uL24 (Gene Name=rplX)

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