Structure of PDB 8pj2 Chain t Binding Site BS01

Receptor Information
>8pj2 Chain t (length=455) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATINIGTIGHV
AHGKSTVVKAISGLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDI
PGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQ
PQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAE
GAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKP
GCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSK
IVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEI
FTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRV
SAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKP
TVDDD
Ligand information
>8pj2 Chain w (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agcagaguggcgcagcggaagcgugcugggcccauaacccagaggucgau
ggaucgaaaccauccucugcuacca
<<<<<<<..<<<<.......>>>>.<<<<<.......>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8pj2 Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining
Resolution3.4 Å
Binding residue
(original residue number in PDB)		L81 Y83 D134 R260 F262 D263 P267 G268 R349 D351
Binding residue
(residue number reindexed from 1)		L64 Y66 D117 R243 F245 D246 P250 G251 R332 D334
External links
PDB RCSB:8pj2, PDBe:8pj2, PDBj:8pj2
PDBsum8pj2
PubMed
UniProtP41091|IF2G_HUMAN Eukaryotic translation initiation factor 2 subunit 3 (Gene Name=EIF2S3)

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