Structure of PDB 7p7t Chain t Binding Site BS01

Receptor Information
>7p7t Chain t (length=82) Species: 1351 (Enterococcus faecalis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRSLKKGPFVDDHLMKKVEAQQGAEKKKVIKTWSRRSTIFPSFVGFTIAV
YDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGH
Ligand information
>7p7t Chain a (length=1521) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccuucggggacaaagugacagguggugcaugguugucgucagc
ucgugucgugagauguuggguuaagucccgcaacgagcgcaacccuuauu
guuaguugccaucauuuaguugggcacucuagcgagacugccggugacaa
accggaggaagguggggaugacgucaaaucaucaugccccuuaugaccug
ggcuacacacgugcuacaaugggaaguacaacgagucgcuagaccgcgag
gucaugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaac
ucgccugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcg
gugaauacguucccgggccuuguacacaccgcccgucacaccacgagagu
uuguaacacccgaagucggugagguaaccuuuuuggagccagccgccuaa
ggugggauagaugauuggggugaagucguaacaagguagccguaucggaa
ggugcggcuggaucaccuccu
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<<....>>>>>>......>
>.>.......<<<<<<<<....>>>>>>>>.......<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.........>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<<.......<<<<<....>>>
>>...<<<<<..>>>>>...>>.>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>...........<<<<<<<......
..>>>>>>>..........>>>>>>....<<<<<<<.........>>>>>
>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<
<<<<..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..
>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....
>>>>>>>>>............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p7t Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
G2 R3 S4 L5 K6 K7 F10 H14 K18 W34 R36 R37 Y52 G54 R55 K70 G72 E73 T77 R78 T79 Y80 H83
Binding residue
(residue number reindexed from 1)
G1 R2 S3 L4 K5 K6 F9 H13 K17 W33 R35 R36 Y51 G53 R54 K69 G71 E72 T76 R77 T78 Y79 H82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7p7t, PDBe:7p7t, PDBj:7p7t
PDBsum7p7t
PubMed35387982
UniProtA0A1B4XKS0

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