Structure of PDB 7ohx Chain t Binding Site BS01

Receptor Information
>7ohx Chain t (length=202) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRAESIVAKTLATSREKERIKRVSILEDKKAKNETQHIASGKDFILKEKT
TYDGKPALLFIVRVRGPLAVNIPNKAFKILSLLRLVETVKLTKNVYPLLK
VIAPYVVPSLSSIRSLIQKRGRIIYKAEPHEIVLNDNNIVEEQLGDHGII
CVEDIIHEIATMGESFSVCNFFLVSGFGSLNRLRKIKQREAESNAATAPV
IE
Ligand information
>7ohx Chain 6 (length=65) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccuucucaaacauucuguuugguagugagugauacucuuuggaguuaacu
ugaaauugccuuaaa
......<<<<<.....>>>>>.....<<<<...<<<<....>>>>..>>>
>..............
Receptor-Ligand Complex Structure
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PDB7ohx Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.3 Å
Binding residue
(original residue number in PDB)
A63 L66 R70 R77 Q91 H92 I93 A94 F99 K132 R146 R148 L151 V153 I155 F160 T171 S278 G279 F280 K288 R292 A304 A305
Binding residue
(residue number reindexed from 1)
A8 L11 R15 R22 Q36 H37 I38 A39 F44 K49 R63 R65 L68 V70 I72 F77 T88 S175 G176 F177 K185 R189 A195 A196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0042134 rRNA primary transcript binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000465 exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0022625 cytosolic large ribosomal subunit
GO:0030687 preribosome, large subunit precursor

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7ohx, PDBe:7ohx, PDBj:7ohx
PDBsum7ohx
PubMed34813592
UniProtP40693|RLP7_YEAST Ribosome biogenesis protein RLP7 (Gene Name=RLP7)

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