Structure of PDB 6spf Chain t Binding Site BS01

Receptor Information
>6spf Chain t (length=86) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANTPSAKKRAKQAEKRRSHNASLRSMVRTYIKNVVKAIDAKDLEKAQAAF
TAAVPVIDRMADKGIIHKNKAARHKSRLSGHIKALS
Ligand information
>6spf Chain a (length=1390) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacaca
ugcaagucgagcggaugaagggagcuugcuccuggauucagcggcagacg
ggugaguaaugccuaggaaucugccugguagugggggauaacguccggaa
acgggcgcuaauaccgcauacguccugagggagaaagugggggaucuucg
gaccucacgcuaucagaugagccuaggucggauuagcuaguugguggggu
aaaggccuaccaaggcgacgauccguaacuggucugagaggaugaucagu
cacacuggaacugagacacgguccagacuccuacgggaggcagcaguggg
gaauauuggacaaugggcgaaagccugauccagccaugccgcgugucuuu
aaguugggaggaagggcaguaaguuaauaccuugcuguuuugacguuacc
aacagaauaagcaccggcuaacuucgugccagcagccgcgguaauacgaa
gggugcaagcguuaaucggaauuacugggcguaaagcgcgcguagguggu
ucagcaaguuggaugugaaauccccgggcucaaccugggaacugcaucca
aaacuacugagcuagaguacgguagagggugguggaauuuccuggaagga
acaccaguggcgaaggcgaccaccuggacugauacugacacugaggugcg
aaagcguggggagcaaacaggauuagauacccugguaguccacgccguaa
acgaugucgacuagccguugggauccuugagaucuuaguggcgcagcuaa
cgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacucaaa
ugaauugacgggggcccgcacaaugcugagaacuuuccagagauggauug
gugccuucgggaacucagacacaggugcugcauggccagcucgugucgug
agauguuggguuaagucccguaacgagcgcaaccuccuuaguuaccagca
ccucgggugggcacucuaaggagacugccggugacaaaccggaggaaggu
gucaagucaucauggcccuuacggccagggcuacacacgugcuacaaugg
ucgguacaaaggguugccaagccgcgagguggagcuaaucccauaaaacc
gaucguaguccggaucgcagucugcaacucgacugcgugaagucggaauc
gcuaguaaucgugaaucagaaugucacggugaauacguucccgggccuug
uacacaccgcccgucacaccaugggaguggguugcuccagaaguagcuag
ucuaaccgcaagggggacgguuaccacggagugauucaugacugggguga
agucguaacaagguagccguaggggaaccugcggcuggau
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<...<..<<<..>>>..>..>.>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<<...
.>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<....
>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<...<<<<<<<..
.....>>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>
.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>..
.......<<<....<<<<....>>>>..>>>..>>.>>>>>>........
..<<<<<......<<<..<..<<........>>..>..>>>.......>>
>>>.......<<<<<((.....<<<<.....<<..))>>.......>>>>
.>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<
<<<<..<<<<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>
>..>>.>>>>>>...<<<<<<<....<<<<<<<.....<<<<.>>>>...
.........<<....>>.>>>>>>>...>>>.>>>>...>>>...>>>>.
...<<<<<<<...<...<<<<.........>>>>...>>>>>>>>.....
.....<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>...<<..)
)>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)
))).]<<<<<.<<<<<<<.<<....<<<.........<.......>....
...<......>....>>>.........<..........<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>....................<<
.......>>..................<<<<<.....>>>>>........
.............>....................................
..................................................
..................................................
....................................>>...>>>>>>>>>
>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<
<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>.
.>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6spf Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.89 Å
Binding residue
(original residue number in PDB)
A2 N3 T4 S6 K9 R10 R17 R18 N21 S23 R25 S26 M27 R29 T30 Y31 P56 R60 D63 K64 K69 N70 A73 R74 H75 K76 S77 R78 H82 K84
Binding residue
(residue number reindexed from 1)
A1 N2 T3 S5 K8 R9 R16 R17 N20 S22 R24 S25 M26 R28 T29 Y30 P55 R59 D62 K63 K68 N69 A72 R73 H74 K75 S76 R77 H81 K83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6spf, PDBe:6spf, PDBj:6spf
PDBsum6spf
PubMed31611393
UniProtA0A072ZDZ9

[Back to BioLiP]