Structure of PDB 6s0x Chain t Binding Site BS01

Receptor Information
>6s0x Chain t (length=81) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVS
LAVKLVDKAAQSNLIHSNKADRIKSQLMTAN
Ligand information
>6s0x Chain a (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
.....<<<<..[.((((.>>>>.<<<<.<<<<<...<<<<<<<.....<<
<.<<<..<<<..<<.<<<<......................>>>>.>>>>
>......<<........<<<<<<<..<<...<<<<<.<.<<<.<....<<
<<<<....>>>>>>......>>>>......<<<.<...........>.>>
>.......<.<.........>>..>.>>>>>..>>>>>>>>>.<<<....
<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<
....>>>...>>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>....<<<.......................>>>......<<<<<
...........<<<<<........>>>>>............>>>>>....
...<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<........<<<......
>>>...........>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>...>>>>....<.<<<<....<...<<<<.........>
>>>...>.>>>>.>..........<<<<<<..<<<<<<<<<<<<<....>
>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<
<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<..<<<<<..
<<<<<<<<<<......<<........>>..........<<<<<<<.....
...<<<......<<<<<....>>>>>.....<<<....>>>....>>>..
......<<<...<<<<<<......<<<<<<<<<....>>>..<<<<....
..>>>>..>>>>>>.....<<<..<<.<<.........<<......>>..
.......>>>>.....<<<<<.....>>>>>.........>>>.......
>.>>>...>>.>>>......>>>>>>>...>>.>>>>>>>>.....<<<<
<<<.....<<<..<<....<<....>>....>>....>>>.....>>>>>
>>......<....<<<<.<<........>>.>>>>....>.....>>>>>
.....<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.
>>....<..<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<
<............>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6s0x Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant.
Resolution2.425 Å
Binding residue
(original residue number in PDB)		N3 A7 K9 R10 V11 T14 K16 E18 R20 N21 Q24 K33 K55 D58 K59 Q62 N64 H67 K70 D72 R73 K75 S76 Q77 M79 T80 N82
Binding residue
(residue number reindexed from 1)		N2 A6 K8 R9 V10 T13 K15 E17 R19 N20 Q23 K32 K54 D57 K58 Q61 N63 H66 K69 D71 R72 K74 S75 Q76 M78 T79 N81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6s0x, PDBe:6s0x, PDBj:6s0x
PDBsum6s0x
PubMed31391518
UniProtW8UXC3

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