Structure of PDB 6fec Chain t Binding Site BS01

Receptor Information
>6fec Chain t (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLMPKKNRIAIYELLFKEGVMVAKKDVHMPKHPELADKNVPNLHVMKAMQ
SLKSRGYVKEQFAWRHFYWYLTNEGIQYLRDYLHLPPEIVPATLRRSR
Ligand information
>6fec Chain A (length=1776) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucuccuacuuggauaa
cugugguaauucuagagcuaauacaugccgacggcgcugacucccuuugu
gugggaugcgugcauuuaucagaucaaaaccaacccggucagcggcggcg
gcuuuggugacucuagauaaccucgggccgaucgcagcccuccguggcgg
cgacgacccauucgaacgucugcccuaucaacuuucgaugguagucgccg
ugccuaccauggugaccacgggugacggggaaucaggguucgauuccgga
gagggagccugagaaacggcuaccacauccaaggaaggcagcaggcgcgc
aaauuacccacucccgacccggggagguagugacgaaaaauaacaauaca
ggacucuuucgaggcccuguaauuggaaugaguccacuuuaaauccuuua
acgaggauccauuggagggcaagucuggucgcagcagccgcgguaauucc
agcuccaauagcguauauuaaaguugcugcaguuaaaaagcucguaguug
gaucuugagggcccgccccucggcgcccccucgaugugucccgcggggcc
cgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcccgagccg
ccuggauaccgcagcuaggaauaauggaauaggaccgcgguucuauuuug
uugguuuucggaacugaggccaugauuaagagggacggccgggggcauuc
guauugcgccgcuagaggugaaauucuuggaccggcgcaagacggaccag
agcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaagucgg
agguucgaagacgaucagauaccgucguaguuccgaccauaaacgaugcc
gacuggcgaugcggcggcguuauucccaugacccgccgggcagcuuccgg
gaaaccaaagucuuuggguuccggggggaguaugguugcaaagcugaaac
uuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuuaa
uuugacucaacacgggaaaccucacccggcccggacacggacaggauuga
cagauugauagcucuuucucgauucugugggugguggugcauggccguuc
uuaguugguggagcgauuugucugguuaauuccgauaacgaacgagacuc
uggcaugcuaacuaguuacgcgacccccgagcggucggcgucccccaacu
ucuuagagggacaaguggcguucagccacccgagauugagcaauaacagg
ucugugaugcccuuagaugucggggcugcacgcgcgcuacacugacuggc
ucagcgugugccuacccuacgccggcaggcgcggguaacccguugaaccc
cauucgugauggggaucggggauugcaauuauuccccaugaacgaggaau
ucccaguaagugcgggucauaagcuugcguugauuaagucccugcccuuu
guacacaccgcccgucgcuacuaccgauuggaugguuuagugaggcccuc
ggaucggcccgccggggucggcccacggcccuggcggagcgcugagaaga
cggucgaacuugacuaucuagaggaaguaaaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((................[[[.
[[[...<....<.....<<..........>>....>.>.......{{...
.....[[[.{..........[[[[[..................<<.....
<<..<.......>..>>......>>..........<<...<<........
..>>...>>..[[..(((((.......<<<<<<<<<<.<........>>>
>..............)))))......]]...<<<...<<......>>...
>>>.]].]]].......}.]]].<<<....<<<.....<<<<<<......
...>>>>>>.>>>......>>>...<<<.<<<<....>>>>....>>>.}
}.<<.<<<..........>>>.>>.<.<<....>>.>...]]]]]]....
.....<<<....<<<.....>>>..>>>...............<<<.<<<
<<.<<<....>>>.>.>>>>..>>>......<..................
.>.........<<<<<((......<<<<.........)).........>>
>>.>>>>>..)))))).]]]............<<.......{{...[[[.
[[....<.<..>.>..........<<<<<...............>>>>>.
........<<<<<..........<<..............<<<.......>
>>....>>.........>>..>>>.......[[....[.(((((.....>
>>>>>>...))))).]...]]....]]....<<<<<<..<...<<<<..<
<<.<<<<<<<<...<<<......>>>......>>>>>>>>.>>>......
.<<....>>...>>>>..>..>>>.>>>...]]]...}}......<<<<<
.....<...<<.............>>...>..>>>>>..........<<<
.<<.<<<..<.<<<<<<.<<<<......>>>>>>>>>>.>..>>>...<<
..>>>>...>>.....>>>......<<......<<<......>>>....>
>...]]]]..<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<....
..<<........>>..........<<<<<.......<<<<<.......<<
.<<<........>>>.>>.....>>>>>....<..<<<....<<<<<<..
...<<<.<<<<......>>...<<<......>>>...>>.>>>....<<<
.......<<<<..<<<<.......<..<<<....>>>>........>>>>
..>>>>........<<<<<.....>>>>>........>>>.....>>.>>
>...>...>>>.>......>>>>>...>>.>>>>.>>>.....<<.<<<.
.......<.......<<<.<<<<....>>>>.>>>....>.........>
>>.>>..........<.<<<<<..........>>>>>>..........>>
>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>
>>.>>.......<<.....<<<.<<....<<<<<<<<.<<...<<<<..<
...<<<<<<<<<<<<<<...........>>>>>>>>>...>>>>>...>.
.>>>>...>>.>>>>>>>>...>>.>>>......>>.........<<<<<
<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6fec Structure of a human cap-dependent 48S translation pre-initiation complex.
Resolution6.3 Å
Binding residue
(original residue number in PDB)
M1 L2 M3 P4 K5 R8 Q50 S51 S54 R55 F62
Binding residue
(residue number reindexed from 1)
M1 L2 M3 P4 K5 R8 Q50 S51 S54 R55 F62
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6fec, PDBe:6fec, PDBj:6fec
PDBsum6fec
PubMed29401259
UniProtP46783|RS10_HUMAN Small ribosomal subunit protein eS10 (Gene Name=RPS10)

[Back to BioLiP]