Structure of PDB 5dat Chain s1 Binding Site BS01

Receptor Information
>5dat Chain s1 (length=216) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKSASDALKGRVVEVC
LADLQGSEDHSFRKIKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQT
LIEANVTVKTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVIS
EILTKEVQGSTLAQLTSKLIPEVINKEIENATKDIFPLQNIHVRKVKLLK
QPKFDVGALMALHGEG
Ligand information
>5dat Chain 6 (length=1795) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccucuacaugguauaacugug
guaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagagau
guauuuauuagauaaaaaaucaaugucuucggacucuuugaugauucaua
auaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaauu
ucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuucaa
cggguaacggggaauaaggguucgauuccggagagggagccugagaaacg
gcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccuaau
ucagggagguagugacaauaaauaacgauacagggcccauucgggucuug
uaauuggaaugaguacaauguaaauaccuuaacgaggaacaauuggaggg
caagucuggugccagcagccgcgguaauuccagcuccaauagcguauauu
aaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguuggc
cgguccgauuuuuucguacuggauuuccaacggggccuuuccuucuggcu
aaccuugaguccuuguggcucuuggcgaaccaggacuuuuacuuugaaaa
aauuagaguguucaaagcaggcguauugcucgaauauauuagcauggaau
aauagaauaggacguuugguucuauuuuguugguuucuaggaccaucgua
augauuaauagggacggucgggggcaucaguauucaauugucagagguga
aauucuuggauuuauugaagacuaacuacugcgaaagcauuugccaagga
cguuuucauuaaucaagaacgaaaguuaggggaucgaagaugaucagaua
ccgucguagucuuaaccauaaacuaugccgacuagggaucgggugguguu
uuuuuaaugacccacucggcaccuuacgagaaaucaaagucuuuggguuc
uggggggaguauggucgcaaggcugaaacuuaaaggaauugacggaaggg
caccaccaggaguggagccugcggcuuaauuugacucaacacggggaaac
ucaccagguccagacacaauaaggauugacagauugagagcucuuucuug
auuuugugggugguggugcauggccguucuuaguugguggagugauuugu
cugcuuaauugcgauaacgaacgagaccuuaaccuacuaaauaguggugc
uagcauuugcugguuauccacuucuuagagggacuaucgguuucaagccg
auggaaguuugaggcaauaacaggucugugaugcccuuagacguucuggg
ccgcacgcgcgcuacacugacggagccagcgagucuaaccuuggccgaga
ggucuugguaaucuugugaaacuccgucgugcuggggauagagcauugua
auuauugcucuucaacgaggaauuccuaguaagcgcaagucaucagcuug
cguugauuacgucccugcccuuuguacacaccgcccgucgcuaguaccga
uugaauggcuuagugaggccucaggaucugcuuagagaagggggcaacuc
caucucagagcggagaauuuggacaaacuuggucauuuagaggaacuaaa
agucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[[.((((((................[[[
.[[[..<<....<<....<<..........>>...>>.>>......{{..
......[[[..{{..{{....[[[...............<.....<<.<<
.......>>.>>......>.........<<<<<..<......>..>>>>>
....((((((......<<<<<<<<<<<<..>>>>..............))
)))).........<<<<..<<<.....>>>.>>>>....]]]...}}}}.
.]]].<<<....<<<....<<<<<<<<.......>>>>>>>>>>>.....
.>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<...
..>>>..>>>...............<<<<<<<<.<..........>.>>>
>>.>>>......<<..<...........>..>>.........<<<<<((.
.....<<<<.....<<..))>>.......>>>>.>>>>>..))))))]]]
].........[[[{{.......{{...[[[.{{....<<<<<<.<<<..<
<<<...............>>>>......>>>.>>>>>>....<<<<<<..
..<<..<<<<.......>>>>..>>....>>>>>>...<<<<<.<<....
...<<...<.......>..<<<.....>>>....>>......>>.>>..>
>>.........[[[..((((((((....>>>>>>>>.)))))))).]]].
....}}....<<<<<<.<<...<<<<..<<..<<<<<<.<...<<<....
..>>>......>.>>>>>>..>>.......<<....>>...>>>>...>>
>>>.>>>...]]]...}}......<<<<<<<...<...<<<<.<.....>
.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<<<<.<<<
........>>>>>>>>>>>..>>>...<<..}}>>...>>.....>>>.]
]].<<<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<
<<..<<.<<<<<<..<<<.<<<<<<......<<........>>.......
...<<<<<......<<<<<........<<.<<<........>>>.>>...
...>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>..
.<<<......>>>...>>.>>>....<<<<<.<<..<<<<..<<<<<.<<
<<<<....>>>>>>...>>>>>..>>>>.>>....<<<<<<.....>>>>
>>.......>>>>>....>>>.>>>...>.>>>>>>>.......>>>>>.
..>>.>>>>.>>>.....<<<<<<<......<<.....<<..<<<<....
>>>>..>>....>>.......>>>>>>>...........<<<<<<.....
.....>>>>>>..........>>>>>>....<<<<<<<<.......>>>>
>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<<..
..<<<<<<<<.<<<..<.<<..<...<<<<<<<.<<<..<<.......>>
...>>>.>>>>>>>...>..>>.>..>>>.>>>>>>>>...>>.>>>>..
.>.>>...>.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dat Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
Resolution3.15 Å
Binding residue
(original residue number in PDB)		P23 K27 H101 R111 V114 K116 W117 Q118 L120 R136 F138 Q146 N148 Q149 V150 K151 R152 H153 Y155 Q157 S158 S159 R165 D203 I204 F205 P206 K214 K216
Binding residue
(residue number reindexed from 1)		P4 K8 H82 R92 V95 K97 W98 Q99 L101 R117 F119 Q127 N129 Q130 V131 K132 R133 H134 Y136 Q138 S139 S140 R146 D184 I185 F186 P187 K195 K197
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030686 90S preribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5dat, PDBe:5dat, PDBj:5dat
PDBsum5dat
PubMed
UniProtP33442|RS3A1_YEAST Small ribosomal subunit protein eS1A (Gene Name=RPS1A)

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