Structure of PDB 8y38 Chain s Binding Site BS01

Receptor Information
>8y38 Chain s (length=82) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAV
YDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGH
Ligand information
>8y38 Chain a (length=1479) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacugauguuagcggcggacgggugaguaac
acguggauaaccuaccuauaagacugggauaacuucgggaaaccggagcu
aauaccggauaauauuuugacgcaugguucaaaagugaaagacggcuguc
acuuauagauggauccgcgcugcauuagcuaguugguaagguaacggcuu
accaaggcaacgaugcauagccgaccugagagggugaucggccacacugg
aacugagacacgguccagacuccuacgggaggcagcaguagggaaucuuc
cgcaaugggcgaaagccugacggagcaacgccgcgugagugaugaagguc
uucggaucguaaaacucuguuauuagggaagaacauauguguaaguaacu
gugcacaucuugacgguaccuaaucagaaagccacggcuaacuacgugcc
agcagccgcgguaauacguagguggcaagcguuauccggaauuauugggc
guaaagcgcgcguaggcgguuuuuuaagucugaugugaaagcccacggcu
caaccguggagggucauuggaaacuggaaaacuugagugcagaagaggaa
aguggaauuccauguguagcggugaaaugcgcagagauauggaggaacac
caguggcgaaggcgacuuucuggucuguaacugacgcugaugugcgaaag
cguggggaucaaacaggauuagauacccugguaguccacgccguaaacga
ugagugcuaaguguuaggggggccccuuagugcugcagcuaacgcauuaa
gcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaauuga
cggggacccgcacaagcgguggagcaugugguuuaauucgaagcaacgcg
aagaaccuuaccaaaucuugacauccucuagagauagaggacagguggug
caugguugucgucagcucgugucgugagauguuggguuaagucccgcaac
gagcgcaacccuuaagcuuaguugccaucaugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuaggagcuagc
cgucgaaggugggacaaaugauuggggugaagucguaacaagguagccgu
aucggaaggugcggcuggaucaccuccuu
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<...<<......>>...>>>>>......<<.......
.<<<<<<<..<<...<<<<<<<.<<<<.....<<<<<<....>>>>>>..
....>>>>......<<<.<.........>.>>>.......<..<.>..>.
.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>
>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<
<.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<
<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<
....>>>>.....>>>>...<<<<<<<.......<.<<<<<<<.......
.>>>>>>>.>........>>>>>>...>..<<<<<(((...<<<<<....
.<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<
((.....<<<<<..<<<.<<<<<<<.<<<<<<<<<.......<<<<<<..
...>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<
<<<....<<<<<<<<...<<<......>>>......>>>>>>>>......
.....<<....>>.>>>>>>>..>>>>>.>>>...>>>..>>>>>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<<<<..<<<<<<<<<<<<.>>>>>>>>>>>>...<<..))>>.....
>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<.<<.<<<.<<..<<<<<<<<<<......<<........>>
..........<<<<<<<......<<.<<<<....>>>>.>>.<<<.<<<.
.<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>
>>>>.....<<<<.<<<<<<...<<<..<..>>>>....>>>>>>.....
<<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>.>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<..>>.>>>.>>
>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<
<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8y38 Synthetic macrolides overcoming MLS B K-resistant pathogens.
Resolution2.58 Å
Binding residue
(original residue number in PDB)
A2 R3 S4 I5 K6 K7 F10 H14 K18 K32 W34 R36 R37 Y52 D53 G54 R55 K70 G72 E73 T77 R78 T79 F80 H83
Binding residue
(residue number reindexed from 1)
A1 R2 S3 I4 K5 K6 F9 H13 K17 K31 W33 R35 R36 Y51 D52 G53 R54 K69 G71 E72 T76 R77 T78 F79 H82
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