Structure of PDB 8wb0 Chain s Binding Site BS01

Receptor Information

>8wb0 Chain s (length=209) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DDEEETYRLWKIRKTIMQLCHDRGYLVTQDELDQTLEEFKAQFGDKPSEG
RPRRTDLTVLVAHNDDPTDQMFVFFPEEPKVGIKTIKVYCQRMQEENITR
ALIVVQQGMTPSAKQSLVDMAPKYILEQFLQQELLINITEHELVPEHVVM
TKEEVTELLARYKLRENQLPRIQAGDPVARYFGIKRGQVVKIIRPSETAG
RYITYRLVQ

Ligand information

>8wb0 Chain X (length=43) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cttcttcatcaactgagccgagcagacgtgcctacggaccatg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8wb0 Structural Visualization of de novo Transcription Initiation.
Resolution	2.94 Å
Binding residue (original residue number in PDB)	I84 K85 T111
Binding residue (residue number reindexed from 1)	I83 K84 T110

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0001054	RNA polymerase I activity
GO:0001055	RNA polymerase II activity
GO:0001056	RNA polymerase III activity
GO:0003677	DNA binding
GO:0003899	DNA-directed 5'-3' RNA polymerase activity

	Biological Process
GO:0006351	DNA-templated transcription
GO:0006362	transcription elongation by RNA polymerase I
GO:0006366	transcription by RNA polymerase II
GO:0042797	tRNA transcription by RNA polymerase III

	Cellular Component
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005665	RNA polymerase II, core complex
GO:0005666	RNA polymerase III complex
GO:0005736	RNA polymerase I complex

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Cellular Component

External links

PDB	RCSB:8wb0, PDBe:8wb0, PDBj:8wb0
PDBsum	8wb0
PubMed	38127763
UniProt	I3LSI7

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