Structure of PDB 8oeq Chain s Binding Site BS01

Receptor Information
>8oeq Chain s (length=171) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSQNVMRELRIEKLVLNICVGESGDRLTRAAKVLEQLSGQTPVQSKARYT
VRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRSKNFSATGNFG
FGIDEHIDLGIKYDPSIGIYGMDFYVVMGRAGARVTRRKRARSTIGNSHK
TNKEDTIQWFKTRYDAEVLDK
Ligand information
>8oeq Chain 1 (length=3217) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuugca
ugcugcgguuuaccgggccagcaucgguuuggagcggcaggauaauggcg
gaggaauguggcacggcuucugcuguguguuauagccucugacgauacug
ccagccuagaccgaggacugcgguuuaccuaggauguuggcauaaugauc
uuaagucgcccgucuugaaacacggaccaaggagucuaacgucuaugcga
guguuuggguguaaaacccguacgcguaaugaaagugaacgaaggugggg
gcccauuagggugcaccaucgaccgauccugauguguucggauggauuug
aguaagagcauagcuguugggacccgaaagauggugaacuaugccugaau
agggugaagccagaggaaacucugguggaggcucguagcgguucugacgu
gcaaaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaacca
ucuaguagcugguuccugccgaaguuucccucaggauagcagaagcucgu
aucaguuuuaugagguaaagcgaaugauuagaagucuugggguugaaaug
accuuaacuuauucucaaacuuuaaauauguaagaaguccuuguugcuua
auugaacguggacaauugaaugaagagcuuuuagugggccauuuuuggua
agcagaacuggcgaugcgggaugaaccgaacgugaaguuaaagugccgga
augcacgcucaucagacaccacaaaagguguuaguucaucuagacagccg
gacgguggccauggaagucggaauccgcuaaggaguguguaacaacucac
cggccgaaugaacuagcccugaaaauggauggcgcucaagcgugcuacuu
auacuucaccgugauugcuguuuugacgcuuucacgaguaggcaggcgug
gaggucagugacgaagccuuugcuguaaagcugggucgaacggccucuag
ugcagaucuuggugguaguagcaaauauucaaaugagaacuuugaagacu
gaaguggggaaagguuccaugucaacagcaguuggacauggguuagucga
uccuaagagauggggaagcuccguuucaacgugcuugauuuuucaggcca
accaucgaaagggaauccgguuaaaauuccggaacuuggauauggauucu
ucacggcaacguaacugaauguggagacgucggcgugagcccugggagga
guuaucuuuucuucuuaacagcuuaucacccuggaauugguuuauccgga
gauggggucuuauggcuggaagagcgcgguaauuuugccgcguccggugc
gcuuacgacgguccuugaaaauccacaggaaggaauaguuuucaugccaa
gucguacucauaaccgcagcaggucuccaagguuaacagccucuaguuga
uagaauaauguagauaagggaagucggcaaaauagauccguaacuucggg
auaaggauuggcucuaaggaucgguuuaacgaucaacuuagaacugguac
ggacaaggggaaucugacugucuaauuaaaacauagcauugugaugguca
gaaagugauguugacacaaugugauuucugcccagugcucugaaugucaa
agugaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacu
cucuuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaau
ggauuaacgagauucccacugucccuaucuacuaucuagcgaaaccacag
ccaagggaacgggcuuggcagaaucagcggggaaagaagacccuguugag
cuugacucuaguuugacauugugaaaagacauggaggguguagaauaagu
gggagcuucggcgccggugaaauaccacuaccucuauaguuuuuuuacuu
auucaaugaagcggagcuggaggucaaacuccacguucuagcauuaagcc
cucugggcgauccggguugaagacauugucagguggggaguuuggcuggg
gcggcacaucuguuaaacgauaacgcagguguccuaagggggacucaugg
agaacagaaaucuccaguagaacaaaaggguaaaaguccccuugauuuug
auuuucagugugaauacaaaccaugaaaguguggccuaucgauccuuuag
ucccucggaauuugaggcuagaggugccagaaaaguuaccacagggauaa
cuggcuuguggcagucaagcguucauagcgacauugcuuuuugauucuuc
gaugucggcucuuccuaucauaccgaagcagaauucgguaagcguuggau
uguucacccacuaauagggaacgugagcuggguuuagaccgucgugagac
agguuaguuuuacccuacugaugaauguuaucgcaauaguaauugaacuu
aguacgagaggaaccguucauucagauaauugguuuuugcggcugucuga
ucaggcaacgccgcgaagcuaccaucugcuggauuauggcugaacgccuc
uaagucagaauccaugcuagaacgcgaugauuuuugcccugcacauuuua
gauggauacgaauaagacuuuagucgcuggaccauagcaggcuggcaacg
gugcgcuuagcggaaaggcuuugugcgcuugccggcggauagcaauguca
acaugcgcggggauaaauccuuugcauacgacuuagauguacaacggagu
auuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagcu
cuuguugucugauuugu
.......................<<<<<<.....<......>......>>
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>>>>..[[[...........<<.<<<<<<...>>>>>>.>>.........
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>.(.......<<<......)>>>....>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....((((
(..<<<<<<)))))..]]]....}..........................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<<<.<.<...
......>>.>.>>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<
<<<<......<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>
>>.>>>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>
>>>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..
<<<..<<<<<.....>>>>>..>>>...<<....>>.......<<<<<..
<<<<....>>>>...>>>>>.<<<<<<<<<..<<....>>>..>>>.>>>
.>>....>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<.
.<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<...
.....>>>>>>>>....>>>>>>>>>...<<.......>>......>>>>
>>...>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<..
.<<<.<<<<<<<.....<<<....<<<....<<<<...<<<<<<.....>
>>>>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<...
...>>>>>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<...
..>>>>>.>>>>....<<<......>>>...<<<<<<<..<<<<(((...
..<<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<<
<.<<<...<<.........>>...>>>.........<<......>>...>
>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>>
..>>>>>>><<<<<..<<.........>>..>>>>>....>>>>>><.<<
<<<<<<.<<......<<<<..<<<....>>>.>>>>...>>>>>>>>>>.
.>.....>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<
.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<
<<<...<<....<<<....>>>..........<<<<<<....>>>>>>..
....>>....>>>..<<<<<........>>>>>))<<<<.<<<<<<<...
..<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<<<
<..{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>..
..>>>>>>.....>>>>>....><<<<<<<......>>>>>>>>>>>...
>>>>>>>.>>>>.........>>>>>>..........>>>..>>>>>>>>
.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..
<<<<.....<<<<<<<.<<.........<.....<<<<<...........
....>>>>><<.<<<<<<<<<<<......>>>>>..>>>>>>.>>.....
.......<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<
.....>>>>......>>>>>>>...<<..<<<..<<<<<<....<<<...
..<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.......>>>
>>>........<...........<<<<<.......>>>>>.....>....
.>>....>>.>>>>>>>..>..>>.>>>>>>>..>>>>>>....>>....
<<<<<........>>>>>....[[[[[..{{{.{{......[[[[.{{[[
[[..<<<<<.<<<<<<<<..<<<<<<<<<<...<.<<.............
...............................>>.>...>>>>>>>>>>..
.<<<<<.....<<<<..<<<<<......>>>>>..............<<<
<...>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<...
..>>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<
<<<.......>>>>>>.....<<...(((>>....>>>>>>>...<<<.<
<<<<.......>>>>.>>>>.<<<....>>>.>>))).......((((((
..((((.>>>>>>))))))))))..........]]]]..}}]]]].....
..<<.<...<<<<<<...<<.......>>...>>>>>>....>.>.>...
....<<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<..
.......>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>
.>>>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<<<..
...............>>>>>..<<<<<...<<<<....<<<<<<<<<<}}
}.>>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<.........
..>>>>>...>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<....
...<<..........<<<<..>>>>......>>.......<<<<<<...<
<<<<<<..<<<......>>>..>>>>>>>.>>>>>>..............
..>>>.>>>>>>..<<<<<<<.............>>....<<<<<<<<<.
<<<....<<<<.<..<<<<<......>>>>>..>>>>>...>>>....>>
>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.3 Å
Binding residue
(original residue number in PDB)
K16 V18 N20 C22 S48 A50 R51 Y52 F57 I59 A66 H68 K94 N95 S97 A98 T99 G103 F104 G105 G124 M125 D126 Y128 K142
Binding residue
(residue number reindexed from 1)
K13 V15 N17 C19 S45 A47 R48 Y49 F54 I56 A63 H65 K91 N92 S94 A95 T96 G100 F101 G102 G121 M122 D123 Y125 K139
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