Structure of PDB 8e5t Chain s Binding Site BS01

Receptor Information
>8e5t Chain s (length=137) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYEPLIDWFTRHEEVMPLTAVPEPKRRFVPSKNEAKRVMKIVRAIREGRI
IPPKKLKEMKEKEKIENYQYDLPPTNEESYNPPEEYLLSPEEKEAWENTE
YSERERNFIPQKYSALRKVPGYGESIRERFERSLDLY
Ligand information
>8e5t Chain 1 (length=743) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaaaagcggaggaaaaga
aaccaaccgggauugccuuaguaacggcgagugaagcggcaaaagcucaa
auuugaaaucugguacggugcccgaguuguaauuuggagagggcaacuug
uaaagugccuucgaagagucgaguuguuuugcagcucuaaguggguggua
aauuccaucuaaagcuaaauauuggcgagagacuuugaaaagagaguaaa
uuguugaaagggaagggcauuugaucagacauggugucacugggccagca
ucaguuuugguggcaggauaaauccauaggaauguagcuugccucgguaa
guauuauagccugugggaauacugccagcugggacugaggacugcgacgu
aagucaaggaugcuggcauaaugguuauaugccgcccgucuugaaacacg
gaccaaggagucuaacgucuaugcgaguguuuggguguaaaacccauacg
cguagguuggggccucgcaagaggugcacaaucgaccgugaguaagagca
uagcuguugggaguuccugccgaaguagaguuaaggugccggaauacacg
cucaucagaggcgcucaagcguguuaccuauacucuaccgucaggguuga
uaugaugcccugacgaguaggcaggcguggaggucagugacgaagccuag
accguaaggucgggucgaacggccucuagugcagaucuuggug
..........................<<<<<<....>>>>>.>...<...
..<<....>>..<<<<<......<<.....>>.....>>>>>..<<<..<
........<<.<<<<<.>>>>>.>>........>....<<<<<<<.<<..
...>>>>>>>>>........<<<<<<<...>>>>>>>.....<<<<<<..
....>>>>>>..>>>....>............<<<<....>>>>......
...............<<<<<.<<<<<<..<..<<<<.>>>>.><<<<<<<
.<<<<<<<<<<<<<<<.....<<<<<<<<<......<<<<<......>>>
>>.......>>>>>>>.>.>.>>>>>.>>>>>>>>>>........<<<..
..>>>.....>>>>>>>....>>>>>>.>>>>>..<<<<........>>>
><<<<<<<...<<<<<<.<<<<<<..<<<<.<<<<<.....>>>>>.>>>
>...<<<<<..<<<<<....>>>>>...>>>>>.<<.....>>....>>>
>>>.>>>>>>..<<.<<<<<<...<<<<<<<..<<<<(((.....<<<<<
<.....<<.))).>>...>>>>>>.>>>>..>>>>>>><<<<<<<<<...
......>>>>>>>>>....>>>>>>..<<<<<<<<.<<......<<<<.<
<<<....>>>>>>>>...>>>>>>>>>>..>>...>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8e5t A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation.
Resolution4.0 Å
Binding residue
(original residue number in PDB)		K263 R264 R265 F266 V267 S269
Binding residue
(residue number reindexed from 1)		K25 R26 R27 F28 V29 S31
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8e5t, PDBe:8e5t, PDBj:8e5t
PDBsum8e5t
PubMed37037974
UniProtQ04660|ERB1_YEAST Ribosome biogenesis protein ERB1 (Gene Name=ERB1)

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