Structure of PDB 8cq7 Chain s Binding Site BS01

Receptor Information
>8cq7 Chain s (length=171) Species: 5476 (Candida albicans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSQNVMRELRIEKLVLNICVGESGDRLTRAAKVLEQLSGQTPVQSKARYT
VRTFGIRRNEKIAVHVTVRGPKAEEILERGLKVKEYQLRSKNFSATGNFG
FGIDEHIDLGIKYDPSIGIYGMDFYVVMGRAGARVTRRKRARSTIGNSHK
TNKEDTIQWFKTRYDAEVLDK
Ligand information
>8cq7 Chain 1 (length=3216) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuugca
ugcgguuuaccgggccagcaucgguuuggagcggcaggauaauggcggag
gaauguggcacggcuucugcuguguguuauagccucugacgauacugcca
gccuagaccgaggacugcgguuuaccuaggauguuggcauaaugaucuua
agucgcccgucuugaaacacggaccaaggagucuaacgucuaugcgagug
uuuggguguaaaacccguacgcguaaugaaagugaacgaaggugggggcc
cauuagggugcaccaucgaccgauccugauguguucggauggauuugagu
aagagcauagcuguugggacccgaaagauggugaacuaugccugaauagg
gugaagccagaggaaacucugguggaggcucguagcgguucugacgugca
aaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaaccaucu
aguagcugguuccugccgaaguuucccucaggauagcagaagcucguauc
aguuuuaugagguaaagcgaaugauuagaagucuugggguugaaaugacc
uuaacuuauucucaaacuuuaaauauguaagaaguccuuguugcuuaauu
gaacguggacaauugaaugaagagcuuuuagugggccauuuuugguaagc
agaacuggcgaugcgggaugaaccgaacgugaaguuaaagugccggaaug
cacgcucaucagacaccacaaaagguguuaguucaucuagacagccggac
gguggccauggaagucggaauccgcuaaggaguguguaacaacucaccgg
ccgaaugaacuagcccugaaaauggauggcgcucaagcgugcuacuuaua
cuucaccgugauugcuguuuugacgcuuucacgaguaggcaggcguggag
gucagugacgaagccuuugcuguaaagcugggucgaacggccucuagugc
agaucuuggugguaguagcaaauauucaaaugagaacuuugaagacugaa
guggggaaagguuccaugucaacagcaguuggacauggguuagucgaucc
uaagagauggggaagcuccguuucaacgugcuugauuuuucaggccaacc
aucgaaagggaauccgguuaaaauuccggaacuuggauauggauucuuca
cggcaacguaacugaauguggagacgucggcgugagcccugggaggaguu
aucuuuucuucuuaacagcuuaucacccuggaauugguuuauccggagau
ggggucuuauggcuggaagagcgcgguaauuuugccgcguccggugcgcu
uacgacgguccuugaaaauccacaggaaggaauaguuuucaugccaaguc
guacucauaaccgcagcaggucuccaagguuaacagccucuaguugauag
aauaauguagauaagggaagucggcaaaauagauccguaacuucgggaua
aggauuggcucuaaggaucgguuuaacgaucaacuuagaacugguacgga
caaggggaaucugacugucuaauuaaaacauagcauugugauggucagaa
agugauguugacacaaugugauuucugcccagugcucugaaugucaaagu
gaagaaauucaaccaagcgcggguaaacggcgggaguaacuaugacucuc
uuaagguagccaaaugccucgucaucuaauuagugacgcgcaugaaugga
uuaacgagauucccacugucccuaucuacuaucuagcgaaaccacagcca
agggaacgggcuuggcagaaucagcggggaaagaagacccuguugagcuu
gacucuaguuugacauugugaaaagacauggaggguguagaauaaguggg
agcuucggcgccggugaaauaccacuaccucuauaguuuuuuuacuuauu
caaugaagcggagcuggaggucaaacuccacguucuagcauuaagcccuc
ugggcgauccggguugaagacauugucagguggggaguuuggcuggggcg
gcacaucuguuaaacgauaacgcagguguccuaagggggacucauggaga
acagaaaucuccaguagaacaaaaggguaaaaguccccuugauuuugauu
uucagugugaauacaaaccaugaaaguguggccuaucgauccuuuagucc
cucggaauuugaggcuagaggugccagaaaaguuaccacagggauaacug
gcuuguggcagucaagcguucauagcgacauugcuuuuugauucuucgau
gucggcucuuccuaucauaccgaagcagaauucgguaagcguuggauugu
ucacccacuaauagggaacgugagcuggguuuagaccgucgugagacagg
uuaguuuuacccuacugaugaauguuaucgcaauaguaauugaacuuagu
acgagaggaaccguucauucagauaauugguuuuugcggcugucugauca
ggcaacgccgcgaagcuaccaucugcuggauuauggcugaacgccucuaa
gucagaauccaugcuagaacgcgaugauuuuugcccugcacauuuuagau
ggauacgaauaagacuuuuuagucgcuggaccauagcaggcuggcaacgg
ugcgcuuagcggaaaggcuuugugcgcuugccggcggauagcaaugucaa
caugcgcggggauaaauccuuugcauacgacuuagauguacaacggagua
uuguaagcaguagaguagccuuguuguuacgaucugcugagauuaagcuc
uuguugucugauuugu
.......................<<<<<<.....<......>......>>
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>>>>..[[[...........<<.<<<<<<...>>>>>>.>>.........
....<<<<<...<<<<<<<<<<<<.<<<<<<<<....<<<<......>>>
>.(.......<<<......)>>>..>.>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....((((
(..<<<<<<)))))..]]]...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<<<..<<<<.
.>>>>..>>>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<<<<
<......<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>>>.
>>>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>>>>
>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<
..<<<<<.....>>>>>..>>>...<<....>>.......<<<<<..<<<
<....>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>>>.>>
....>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<
<....<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<......
..>>>>>>>>....>>>>>>>>>...<<.......>>......>>>>>>.
..>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<...<<
<.<<<<<<<.....<<<....<<<....<<<<...<<<<<.......>>>
>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<......
>>>>>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.....>
>>>>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.....<
<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<<<.<
<<...<<.........>>...>>>.........<<......>>...>>>>
>...>>>>>>>>>>>>>..........))).>>...>>>>>>.>>>>..>
>>>>>><<<<<..<<.........>>..>>>>>....>>>>>>..<<<<<
<<<.<<......<<<<..<<<....>>>.>>>>...>>>>>>>>>>....
....>>>>>><<.....<<.....<<<<<<.......>>>>>><<<<...
..<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<
...<<....<<<....>>>..........<<<<<<....>>>>>>.....
.>>....>>...<<<<<........>>>>>))<<<<.<<<<<<<.....<
<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<<<<..
{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>....>
>>>>>.....>>>>>....><<<<<<<......>>>>>>>>>>>...>>>
>>>>.>>>>.........>>>>>>..........>>>..>>>>>>>>>>>
>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>..<<<
<.....<<<<<<<.<<...............<<<<<..............
.>>>>><<.<<<<<<<<<<<......>>>>>..>>>>>>.>>........
....<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<<...
..>>>>......>>>>>>>...<<..<<<..<<<<<<....<<<.....<
<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.......>>>>>>
........<...........<<<<<.......>>>>>.....>.....>>
....>>.>>>>>>>.....>>.>>>>>>>..>>>>>>....>>....<<<
<<........>>>>>....[[[[[..{{{.{{......[[[[.{{[[[[.
.<<<<<.<<<<<<<<..<<<<<<<<<<...<.<<................
............................>>.>...>>>>>>>>>>...<<
<<<.....<<<<..<<<<<......>>>>>..............<<<<..
.>>>>..>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<.....>
>>..<<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<
.......>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<
<.......>>>>.>>>>.<<<....>>>.>>))).......((((((..(
(((.>>>>>>))))))))))..........]]]]..}}]]]].......<
<.<...<<<<<<...<<.......>>...>>>>>>....>.>.>......
.<<<<<.<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....}}..}}}.]]]]]....<<<<<<<<..<<<<...<<<<<.....
............>>>>>..<<<<<...<<<<....<<<<<<<<<<}}}.>
>>>>..>>>>>...>>>>..>>>>>.<<<<...<<<<<...........>
>>>>...>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<.<.....
<<..........<<<......>>>......>>.......<<<<<<...<<
<<<<<..<<<......>>>..>>>>>>>.>>>>>>..............>
.>>>.>>>>>>..<<<<<<<.............>>....<<<<<<<<<.<
<<....<<<<.<..<<<<<......>>>>>..>>>>>...>>>....>>>
>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8cq7 Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement
Resolution3.2 Å
Binding residue
(original residue number in PDB)
K16 V18 N20 C22 S48 A50 R51 Y52 F57 I59 A66 H68 K94 N95 S97 A98 T99 G103 F104 G105 G124 M125 D126 Y128 K142
Binding residue
(residue number reindexed from 1)
K13 V15 N17 C19 S45 A47 R48 Y49 F54 I56 A63 H65 K91 N92 S94 A95 T96 G100 F101 G102 G121 M122 D123 Y125 K139
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