Structure of PDB 7oqe Chain s Binding Site BS01

Receptor Information
>7oqe Chain s (length=65) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LANLIDYKLRVLTQDGRVYIGQLMAFDKHMNLVLNECIEERVPKVEKRVL
GLTILRGEQILSTVV
Ligand information
>7oqe Chain 2 (length=143) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guguaguaucuguucuuuucaguguaacaacugaaaugaccucgaggcuc
auacacauuuuuuggcaggacgggaagaggagacgucgcgacccucgcag
agucguucuugacuuggucgcuugauguuucuucuucccguuc
.................<<<<<<......>>>>>><<<<<<<..>>>.>>
>>................<<<<<<<<<<.<<<<<<<<<<<<.<<.....<
<<<<<....>>>>>>>>>>>>..>>>>>>>>.>>>>>>>>>>.
Receptor-Ligand Complex Structure
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PDB7oqe Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Resolution5.9 Å
Binding residue
(original residue number in PDB)
H40 E90
Binding residue
(residue number reindexed from 1)
H29 E58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0070990 snRNP binding
Biological Process
GO:0000245 spliceosomal complex assembly
GO:0000387 spliceosomal snRNP assembly
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0036261 7-methylguanosine cap hypermethylation
GO:1903241 U2-type prespliceosome assembly
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005682 U5 snRNP
GO:0005685 U1 snRNP
GO:0005686 U2 snRNP
GO:0005687 U4 snRNP
GO:0005737 cytoplasm
GO:0032991 protein-containing complex
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0071001 U4/U6 snRNP
GO:0071004 U2-type prespliceosome
GO:0071013 catalytic step 2 spliceosome
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7oqe, PDBe:7oqe, PDBj:7oqe
PDBsum7oqe
PubMed34349264
UniProtP40018|RSMB_YEAST Small nuclear ribonucleoprotein-associated protein B (Gene Name=SMB1)

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