Structure of PDB 7nhl Chain s Binding Site BS01

Receptor Information
>7nhl Chain s (length=63) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVCYFTANGITHIDYKDTELLKRFISERGKILPRRVTGTSAKYQRMLTTA
IKRSRHMALLPYV
Ligand information
>7nhl Chain a (length=1538) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuaggggguuucccgc
cccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacgac
cgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugga
gcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugaca
uccuuugacaacucuagagauagagccuuccggacaaagugacagguggu
gcaugguugucgucagcucgugucgugagauguuggguuaagucccgcaa
cgagcgcaacccuuaagcuuaguugccaucauuaaguugggcacucuaag
uugacugccggugacaaaccggaggaagguggggaugacgucaaaucauc
augccccuuaugauuugggcuacacacgugcuacaauggacaauacaaag
ggcagcgaaaccgcgaggucaagcaaaucccauaaaguuguucucaguuc
ggauuguagucugcaacucgacuacaugaagcuggaaucgcuaguaaucg
uagaucagcaugcuacggugaauacguucccgggucuuguacacaccgcc
cgucacaccacgagaguuuguaacacccgaagccgguggaguaaccuuuu
aggagcuagccgucgaaggugggacaaaugauuggggugaagucguaaca
agguagccguaucggaaggugcggcuggaucaccuccu
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<<...<<<.........>.>>...>>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<.<<<<<<..>>>>>>>>>.
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
.....<.<<<<<<<........>>>>>>>.>........>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>.>..........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<<<.....>>
>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<
<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<
<<<<<<<<<......<<........>>..........<<<<<<<......
<<<<<<.....<<<<<....>>>>>..........>>>>.>>.<<<.<<<
..<<<<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>
>>>>>.....<<<<.<<<<<<<..<<<..<<......>>>>>...>>>>>
>>.....<<<<<.....>>>>>........>>>>.........>>>...>
>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<
<<..<<...<<<....>>>...>>....>>>.....>>>>>>>......<
..<.<<<<<<<........>>>>>>>>...>.....>>>>>>....<<<<
<<<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..
<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...
>>>.>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.
....<<<<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7nhl Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		V15 T19 A20 K43 I44 P46 R47 R48 K55 Q57 R58 T61 K65 R66 H69 Y75
Binding residue
(residue number reindexed from 1)		V2 T6 A7 K30 I31 P33 R34 R35 K42 Q44 R45 T48 K52 R53 H56 Y62
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nhl, PDBe:7nhl, PDBj:7nhl
PDBsum7nhl
PubMed34117249
UniProtQ2G111|RS18_STAA8 Small ribosomal subunit protein bS18 (Gene Name=rpsR)

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