Structure of PDB 6zsd Chain s Binding Site BS01

Receptor Information
>6zsd Chain s (length=370) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VARYPPIVASMTADSKAARLRRIERWQATVHAAESVDEKLRILTKMQFMK
YMVYPQTFALNADRWYQYFTKTVFLSGLPAALRAVACDCLLQEHFYLRRR
RRVHRYEESEVISLPFLDQLVSTLVGLLSPHNPALAAAALDYRCPVHFYW
VRGEEIIPRGHRRGRIDDLRYQIDDKPNNQIRISKQLAEFVPLDYSVPIE
IPTIKCKPDKLPLFKRQYENHIFVGSKTADPCCYGHTQFHLLPDKLRRER
LLRQNCADQIEVVFRANAIASLFAWTGAQAMYQGFWSEADVTRPFVSQAV
ITDGKYFSFFCYQLNTLALTTQADQNNPRKNICWGTQSKPLYETIEDNDV
KGFNDDVLLQIVHFLLNRPK
Ligand information
>6zsd Chain XA (length=1499) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
auccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuuggac
acuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguag
gccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaaa
ucccaaacauauaacugaacuccucacacccaauuggaccaaucuaucac
ccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccucc
gcauaagccugcgucagauaacaacugacaauuaacagcccaauaucuac
aaucaaccaacaagucauuauuacccucacugucaacccaacacaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuuacc
ccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagaggca
ccgccugcccagugacacauguuuaacggccgcgguacccuaaccgugca
aagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggcuc
cacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugccc
gugaagaggcgggcauaacacagcaagacgagaagacccuauggagcuuu
aauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguugg
ggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacuuc
accagucaaagcgaaccucaauugauccaauaacuugaccaacggaacaa
guuacccuagggauaacagcgcaauccuauucuagaguccauaucaacaa
uaggguuuacgaccucgauguuggaucaggacaucccgauggugcagccg
cuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguu
cagaccggaguaauccaggucgguuucuaucuacuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccguaa
augauaucaucucaacuuagaauacccacacccacccaagaacaggguu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
.>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>>
.<.<<<......>>>.>..<<<.<<<...<..............<....<
<<.........>>>....>.......<<<......>>>............
...............>...>>>>>>........>>>>>>...<<<<<...
...>>>>>.........>>>>>><......<<..<<<....>>><<<<..
<<<<........<<<<<.......>>>>>......<<<...<<<<.....
..................>>>>.......>>>.....<<......>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<<<
<<<..<<<.........>>>...<<<<<<.............>>>>>>..
..<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>..
......<...........<<<<<<.....>>>>>>.....>....>>>..
..>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<<<
<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<..
<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<..
...>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<..
...>>>>..>>>....>>.........<<<....>>>............>
>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>
>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>
>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>..
..<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<......<
....>.....>>>.>>><<<<<...<<<....>>>.>>>>>......<<<
................>>>..............<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zsd Structural basis of mitochondrial translation.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		A49 S50 T52 A53 D54 S55 K56 A57 R59 R62 W66 K85 M86 M89 Y94 T97 F98 R160 R162 R165 Y166 R219 G220 H221 R222 R223 R225 K270 P272 F274 Q277 D304 K305 R307 R310 R313
Binding residue
(residue number reindexed from 1)		A9 S10 T12 A13 D14 S15 K16 A17 R19 R22 W26 K45 M46 M49 Y54 T57 F58 R100 R102 R105 Y106 R159 G160 H161 R162 R163 R165 K210 P212 F214 Q217 D244 K245 R247 R250 R253
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0006915 apoptotic process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zsd, PDBe:6zsd, PDBj:6zsd
PDBsum6zsd
PubMed32812867
UniProtQ9NP92|RT30_HUMAN Large ribosomal subunit protein mL65 (Gene Name=MRPS30)

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