Structure of PDB 6spf Chain s Binding Site BS01

Receptor Information
>6spf Chain s (length=80) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRSLKKGPFIDLHLLKKVEVAVEKNDRKPIKTWSRRSMILPHMVGLTIAV
HNGRQHVPVLVNEDMVGHKLGEFAATRTYR
Ligand information
>6spf Chain a (length=1390) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacaca
ugcaagucgagcggaugaagggagcuugcuccuggauucagcggcagacg
ggugaguaaugccuaggaaucugccugguagugggggauaacguccggaa
acgggcgcuaauaccgcauacguccugagggagaaagugggggaucuucg
gaccucacgcuaucagaugagccuaggucggauuagcuaguugguggggu
aaaggccuaccaaggcgacgauccguaacuggucugagaggaugaucagu
cacacuggaacugagacacgguccagacuccuacgggaggcagcaguggg
gaauauuggacaaugggcgaaagccugauccagccaugccgcgugucuuu
aaguugggaggaagggcaguaaguuaauaccuugcuguuuugacguuacc
aacagaauaagcaccggcuaacuucgugccagcagccgcgguaauacgaa
gggugcaagcguuaaucggaauuacugggcguaaagcgcgcguagguggu
ucagcaaguuggaugugaaauccccgggcucaaccugggaacugcaucca
aaacuacugagcuagaguacgguagagggugguggaauuuccuggaagga
acaccaguggcgaaggcgaccaccuggacugauacugacacugaggugcg
aaagcguggggagcaaacaggauuagauacccugguaguccacgccguaa
acgaugucgacuagccguugggauccuugagaucuuaguggcgcagcuaa
cgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacucaaa
ugaauugacgggggcccgcacaaugcugagaacuuuccagagauggauug
gugccuucgggaacucagacacaggugcugcauggccagcucgugucgug
agauguuggguuaagucccguaacgagcgcaaccuccuuaguuaccagca
ccucgggugggcacucuaaggagacugccggugacaaaccggaggaaggu
gucaagucaucauggcccuuacggccagggcuacacacgugcuacaaugg
ucgguacaaaggguugccaagccgcgagguggagcuaaucccauaaaacc
gaucguaguccggaucgcagucugcaacucgacugcgugaagucggaauc
gcuaguaaucgugaaucagaaugucacggugaauacguucccgggccuug
uacacaccgcccgucacaccaugggaguggguugcuccagaaguagcuag
ucuaaccgcaagggggacgguuaccacggagugauucaugacugggguga
agucguaacaagguagccguaggggaaccugcggcuggau
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<...<..<<<..>>>..>..>.>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<<...
.>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<....
>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<...<<<<<<<..
.....>>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>
.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>..
.......<<<....<<<<....>>>>..>>>..>>.>>>>>>........
..<<<<<......<<<..<..<<........>>..>..>>>.......>>
>>>.......<<<<<((.....<<<<.....<<..))>>.......>>>>
.>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<
<<<<..<<<<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>
>..>>.>>>>>>...<<<<<<<....<<<<<<<.....<<<<.>>>>...
.........<<....>>.>>>>>>>...>>>.>>>>...>>>...>>>>.
...<<<<<<<...<...<<<<.........>>>>...>>>>>>>>.....
.....<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>...<<..)
)>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)
))).]<<<<<.<<<<<<<.<<....<<<.........<.......>....
...<......>....>>>.........<..........<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>....................<<
.......>>..................<<<<<.....>>>>>........
.............>....................................
..................................................
..................................................
....................................>>...>>>>>>>>>
>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<
<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>.
.>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spf Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		P2 R3 S4 K6 K7 F10 D12 L13 H14 K17 K18 I31 K32 W34 R37 M39 I40 V51 H52 N53 G54 R55 Q56 H57 M66 V67 G68 H69 L71 G72 E73 F74 R78 T79 Y80 R81
Binding residue
(residue number reindexed from 1)		P1 R2 S3 K5 K6 F9 D11 L12 H13 K16 K17 I30 K31 W33 R36 M38 I39 V50 H51 N52 G53 R54 Q55 H56 M65 V66 G67 H68 L70 G71 E72 F73 R77 T78 Y79 R80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6spf, PDBe:6spf, PDBj:6spf
PDBsum6spf
PubMed31611393
UniProtE2RXT2

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