Structure of PDB 7unr Chain r Binding Site BS01

Receptor Information

>7unr Chain r (length=62) Species: 208964 (Pseudomonas aeruginosa PAO1)

FTAEGVKEIDYKDLNTLKAYVSETGKIVPSRITGTKAKYQRQLATAIKRA
RYLALLPYTDSH

Ligand information

>7unr Chain a (length=1522)

gaacugaagaguuugaucauggcucagauugaacgcuggcggcaggccua
acacaugcaagucgagcggaugaagggagcuugcuccuggauucagcggc
ggacgggugaguaaugccuaggaaucugccugguagugggggauaacguc
cggaaacgggcgcuaauaccgcauacguccugagggagaaagugggggau
cuucggaccucacgcuaucagaugagccuaggucggauuagcuaguuggu
gggguaaaggccuaccaaggcgacgauccguaacuggucugagaggauga
ucagucacacuggaacugagacacgguccagacuccuacgggaggcagca
guggggaauauuggacaaugggcgaaagccugauccagccaugccgcgug
ugugaagaaggucuucggauuguaaagcacuuuaaguugggaggaagggc
aguaaguuaauaccuugcuguuuugacguuaccaacagaauaagcaccgg
cuaacuucgugccagcagccgcgguaauacgaagggugcaagcguuaauc
ggaauuacugggcguaaagcgcgcguaggugguucagcaaguuggaugug
aaauccccgggcucaaccugggaacugcauccaaaacuacugagcuagag
uacgguagagggugguggaauuuccuguguagcggugaaaugcguagaua
uaggaaggaacaccaguggcgaaggcgaccaccuggacugauacugacac
ugaggugcgaaagcguggggagcaaacaggauuagauacccugguagucc
acgccguaaacgaugucgacuagccguugggaucgaucuuaguggcgcag
cuaacgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacu
caaaugaauugacgggggcccgcacaagcgguggagcaugugguuuaauu
cgaagcaacgcgaagaaccuuaccuggccuugacaugcugagaacuuucc
agagauggauuggugccuucgggaacucagacacaggugcugcauggcug
ucgucagcucgugucgugagauguuggguuaagucccguaacgagcgcaa
cccuuguccuuaguuaccagcaccucgggugggcacucuaaggagacugc
cggugacaaaccggaggaagguggggaugacgucaagucaucauggcccu
uacggccagggcuacacacgugcuacaauggucgguacaaaggguugcca
agccgcgagguggagcuaaucccauaaaaccgaucguaguccggaucgca
gucugcaacucgacugcgugaagucggaaucgcuaguaaucgugaaucag
aaugucacggugaauacguucccgggccuuguacacaccgcccgucacac
caugggaguggguugcuccagaaguagcuagucuaaccgcaagggggacg
guuaccacggagugauucaugacuggggugaagucguaacaagguagccg
uaggggaaccugcggcuggauc

........<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<....
.<<<.<<<..<<<..<<.<<....<<<<<<..>>>>>>....>>.>>>>>
......<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<
<<....>>>>>>......>>.>.....<<<....>>>....<<<<<<..<
<....>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>>>>...>>>
>>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<
<<<......<<<<<..>>>>>.....>>>>...<.<<<<<......<<<<
<<<<<<.......>>>>>>>>>>........>>>>>....>..<<<<<((
(...<<<<<.....<<.)))>>.......>>>>>>>>>>..>>>>>>>>>
..........<<<((.....<<<<...<<<.<<<<<<..<<<<<<<<<<.
.....<<<<<<.....>>>>>>....>>>>>>>>..>>.>>>>>>...<<
<<<<<<...<<<<<<<....<<<<<<<<<..<<<......>>>.....>>
>>>>>>>...........<<....>>.>>>>>>>..>>>>.>>>>...>>
>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>
>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>>>>>>>...<
<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>
>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......
<<........>>..........<<<<<<<......<<<<<<<......<<
<....>>>.......<<....>>..>>>>>.>>.<<<.<<<..<<<<<<.
......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>....
.<<<<.<<<<<<<...<<..<<<.....>>>>>....>>>>>>>.....<
<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>>
...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..
.<<<....>>>...>>....>>>.....>>>>>>>......<....<<<<
<<<........>>>>>>>....>.....>>>>>>....<<<<<<<.....
....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<
<.<<<..<<<<<<<<<<<<....<<<<<<.<<<<..<<....>>.>>>>>
>>>>>...>>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<
<<<<....>>>>>>>>>.....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7unr Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): K38 I39 P41 S42 R53 K60 R61
• Binding residue (residue number reindexed from 1): K26 I27 P29 S30 R41 K48 R49

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7unr, PDBe:7unr, PDBj:7unr
• PDBsum: 7unr
• UniProt: Q9HUN0|RS18_PSEAE Small ribosomal subunit protein bS18 (Gene Name=rpsR)