Structure of PDB 7uck Chain r Binding Site BS01

Receptor Information
>7uck Chain r (length=124) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGV
EPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNK
YHPDLRMAAIRRASAILRSQKPVM
Ligand information
>7uck Chain 5 (length=3546) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacuccccggcgccggggggcccaaguccuucu
gaucgaggcccagcccguggacggugugaggccgguagcggcccccggcg
cgccgggcccgggucuucccggagucggguugcuugggaaugcagcccaa
agcgggugguaaacuccaucuaaggcuaaauaccggcacgagaccgauag
ucaacaaguaccguaagggaaaguugaaaagaacuuugaagagagaguuc
aagagggcgugaaaccguuaagagguaaacgggugggguccgcgcagucc
gcccggaggauucaacccggcggccgguccggccgugccggcggggcgga
ucucccgcucccgucggcgggggaccgccccccggccggcgaccggccgc
cgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccgggacg
gcugggaaggccccggcggggaagguggcccgggggccccggguguuaca
gccccgccccggcagcagcagcucgccgaaucccggggccgagggagcga
gacccgugccgccgcgcucuccccccugggggggccgggccaccccuccc
acggcgcgaccgcuggggcggacuguccagugcgccccgggcgggucgcg
ccgucgggcccgggggccacggcgucccccgcgagcgcacggggucggcg
gcgaugucggcuacccacccgacccgucuugaaacacggaccaaggaguc
uaacacgugcgcgagucgggggcuacgaaagccgccguggcgcaaugaag
gugaaggccggcggcgccgccggccgaggugggaucccgaggccuuccag
uccgccgagggcgcaccaccggcccgucucgcccgccgcgccggggaggu
ggagcacgagcgcacguguuaggacccgaaagauggugaacuaugccugg
gcagggcgaagccagaggaaacucugguggagguccguagcgguccugac
gugcgaaucggucguccgaccuggguauaggggcgaaagacuaaucgaac
caucuaguagcugguucccuccaaaguuucccucaggauagcuggcgcuc
uccgcaguuuuauccgguaaagcgaaugauuagaggucuuggggccgaaa
cgaucucaaccuauucucaaacuuuaaauggguaagaagcccggcucgcu
gguguggagccgggcguggaaugcgagugccuagugggccacuuuuggua
agcagaacuggcgcugcgggaugaaccgaacgccggguuaaggcgcccga
ugccgacgcucaucagaccccagaaaagguguugguugauauagacagca
ggaugguggccauggaagucggaauccgcuaaggaguguguaacaacuca
ccugccgaaucaacuagcccugaaaauggauggcgcuggagcgucgggcc
cauacccggccgucgcuggcagucggcagagcgagaaagagaguggcgcg
gacgcuacgccgcgacgaguaggagggccgcugcggugagccuugaagcc
uagggcgcgggcccggguggagccgccgcaggugcagaucuuggugguag
uagcaaauauucaaacgagaacuuugaaggccgaaguggagaaggguucc
augugaacagcaguugaacaugggucagucgguccugagagaugggcgag
cgccguuccgaagggacgggcgauggccuccguugcccucagccgaucga
aagggagucggguucagauccccgaauccggaguggcggagaugggcgcc
gcgaggcguccagugcgguaacgcgaccgaucccggagaagccggcggga
gccccggggagaguucucuuuucuuugugaagggcagggcgcccuggaau
ggguucgccccgagagaggggcccgugccuuggaaagcgucgcgguuccg
gcggcguccggugagcucucgcuggcccuugaaaauccgggggagagggu
guaaaucucgcgccgggccguacccauauccgcagcaggucuccaaggug
aacagccucuggcauguuggaacaauguagguaagggaagucggcaagcc
ggauccguaacuucgggauaaggauuggcucuaagggcuggcagccgacu
uagaacuggugcggaccaggggaauccgacuguuuaauuaaaacaaagca
ucgcgaaggcccgcggcggguguugacgcgaugugauuucugcccagugc
ucugaaugucaaagugaagaaauucaaugaagcgcggguaaacggcggga
guaacuaugacucucuuaagguagccaaaugccucgucaucuaauuagug
acgcgcaugaauggaugaacgagauucccacugucccuaccuacuaucca
gcgaaaccacagccaagggaacgggcuuggcggaaucagcggggaaagaa
gacccuguugagcuugacucuagucuggcacggugaagagacaugaucgu
uuuuucacugacccggugaggcgggggggcgagccgggcucucgcuucug
gcgccaagcgcccggccggccgggcgcgacccgcuccggggacagugcca
gguggggaguuugacuggggcgguacaccugucaaacgguaacgcaggug
uccuaaggcgagcucagggaggacagaaaccucccguggagcagaagggc
aaaagcucgcuugaucuugauuuucaguacgaauacagaccgugaaagcg
gggccucacgauccuucugaccuuuuggguuuuaagcaggaggugucaga
aaaguuaccacagggauaacuggcuuguggcggccaagcguucauagcga
cgucgcuuuuugauccuucgaugucggcucuuccuaucauugugaagcag
aauucaccaagcguuggauuguucacccacuaauagggaacgugagcugg
guuuagaccgucgugagacagguuaguuuuacccuacugaugauguguug
uugccaugguaauccugcucaguacgagaggaaccgcagguucagacauu
ugguguaugugcuuggcugaggagccaauggggcgaagcuaccaucugug
ggauuaugacugaacgccucuaagucagaaucccgcccaggcggaacgau
agcgccggagccucgguuggccucggauagccggucccccgccggggucc
ggugcggagagcccuucgucccgggaaacggggcggccggaaagggggcc
gcccucucgcccgucacgcaccgcacguucguggggaaccuggcgcuaaa
ccauucguagacgaccugcuucugggucgggguuucguacguagcagagc
agcugcugcgaucuauugaaagucagcccucgacacaaggguuugu
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<....<<<<<<<<..<<<<<<<<....<<<<..
....>>>>.....((......<<<.....))>>>...>.>>>>>>>...>
>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>>>>>..
...(((((..<<<<<<)))))..]]]........................
..........<<....>>...............<<<<....>>>>.....
.............................<<<<<<<<..<<<.<<...<<
<<<<<<.<<<.....<<<<<<<<<....<<<<<<<.<<<<<.<<<<<<<.
<<<<<<<<<......>>>>>>>>>>>>>>>>>>>>>>>>>...>>>..>>
>>>>>>>......>>>.>>>.>>>>>...<<<<<<<<<<<<<<<<<<<<<
<<...<<..<<<..<<<<<<<......<<<<<<<<.>>>>>>>>......
.>>>>>>>..>>>.........>>>>>>..>>>>>>>>>>>.....<<..
...{.>>......<<<<<<.<<<<<<..>>>>>>.<<<<<<..<<<.<<<
<<<<<<<<<<<<<<<<<<<<.<<<<..>>>>.>>>>>>.>>>.>>>>>>>
>>>>.>>>...>>>>>>>.>>...........>>>>>>.....>>>.>>>
>>...>>>>>...>>>>>>>>..<<<<........>>>><<<<<<....<
<<<<<<<<<<<<..<<<...<<<<.....>>>>.....>>>...<<....
>>...<<<<<<<<....>>>>>>>>..<<<<<...<<<..<<<...(((.
[[.>>>..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>
>>.>>....>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<
<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<.
.......>>>>.>>>....>>>>>>>>>...<<.......>>......>>
>>>>......>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<
...<<<.<<<<<<<<<...<<<....<<<..<.<<<..<<<<.<......
...>.>>>>>>>.>..>>>..>.>>...>>>>>>>...<<<<<<<<<.<.
.....>>>>>>>>>>....>>>>>>>>>>>>..>>..<<<<.<<<<<...
..>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<(((...
....<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<
<<.<<.....................>>.........<<......>>...
>>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>..>>>
...>>>>>>><<<<<<.<<<........}...........]].)))....
........>>>>>>>>>....>>>>>>.<.<<<<<<<<.<<......<<<
<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<...
..<<.....<<<<<<.......>>>>>>.<<<.....<<<<<.<<...<<
<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<...
.>>>..........<<.<<<<<<<<<...>>>>>>>>>>>......>>..
..>>>..<<<<<........>>>>>))<<<<....<<<<<..<<<<<<<<
....>>>>>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<
<<<<<<<<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<.....
<<<.....>>>.....>>>>>>>>..>>>>>.....<<<<<<<.......
>>>>>>>>>>>.>.>>>>>>>>>>>>.........>>>>>>>..>.....
.....>>.>>>.>>>>.>>>..>>.....<<......>>>>>>>.<<<<.
....>>>>..>>>....<<<<.....<<<<<<<.<<.........<....
.<<<<<....<<..>>.....>>>>><<.<<<<<<<<<<<.>>>>>..>>
>>>>.>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<
<<.....<<.....<<<<....>>>>.....>>..>>>>..>>>>><<<<
<<.......>>>>>>........<...........<<<<<.......>>>
>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>>>>..>>>>
>>....>>....<<<<<........>>>>>....[[[[[..{{{.{{...
...[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<<<<<......>>
>>>>>>>>...<<<<<.....<<<<..<<.<.<<<>>.>>.>>.......
.......<<<<<<<<<..>>>>>>>>>..>>>>..>>>>>....>>>>>>
>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>>>.
.<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.(((>>
....>>>>>>>...<<<..<<<<.......>>>>..>>>.<<<....>>>
.>>)))]......((((((..(((..>>>>>>.)))))))))........
..]]]]..}}]]]].......<<.<.<.<<<<<<...<<.......>>..
.>>>>>>...>>.>.>.......<<<<<.<<<<<<..<.<.<<<<<....
..>>>>>...>.>.<<<.........>>>.....>>>>>..>...>>>.>
>....<<<<<<<....>>>.>>>>....}}..}}}.]]]]].....<<<<
<<.<..<<<..<.<<<<<.................>>>>>.><<<<....
<<<<....<<.<<<<<<<}}}.>>>>>..>>.>>...>>>>...>>>><<
<<<...<<<<<...........>>>>>...>>>>>.>>>...>.>>>>>>
.<<<<<<<..<<<<....<<<........<<<<<..<<<<<.>>>>>.>>
>>>.......>>>...<<<..<<<<....<<<<<<<<<........>>>>
>>.>>>...>>>>..>>>..............>>>>..>>.>>>>>.<<<
<<.<.............>....<<.<<<<<<<.<<.....<<<<.<..<<
<<<.>>>>>..>>>>>....>>....>>>>.>>>.>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7uck Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
W7 R11 S15 K19 K22 K33 R35 N36 S37 R39 R46 R66 R67 S68 K84 N85 R87 R94 H95 R98 K99 N100 K101 R107 M108 R112
Binding residue
(residue number reindexed from 1)
W6 R10 S14 K18 K21 K32 R34 N35 S36 R38 R45 R65 R66 S67 K83 N84 R86 R93 H94 R97 K98 N99 K100 R106 M107 R111
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7uck, PDBe:7uck, PDBj:7uck
PDBsum7uck
PubMed35679869
UniProtG1U7L1|RL28_RABIT Large ribosomal subunit protein eL28 (Gene Name=RPL28)

[Back to BioLiP]