Structure of PDB 7qgg Chain r Binding Site BS01

Receptor Information
>7qgg Chain r (length=131) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGV
EPAADGKGVVVVMKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNK
YRPDLRMAAIRRASAILRSQKPVVVKRKRTR
Ligand information
>7qgg Chain t (length=3679) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccgcgcgcggcgcgggaaaugug
gcguacggaagacccacuccccggcgccgcucguggggggcccaaguccu
ucugaucgaggcccagcccguggacggugugaggccgguagcggcccccg
gcgcgcgcccgggucuucccggagucggguugcuugggaaugcagcccaa
agcgggugguaaacuccaucuaaggcuaaauaccggcacgagaccgauag
ccaacaaguaccguaagggaaaguugaaaagaacuuugaagagagaguuc
aagagggcgugaaaccguuaagagguaaacgggugggguccgcgcagucc
gcccggaggauucaacccggcggcgcgcguccggccgugccgguggccgg
cggaucuuucccgcucccggugucggcgggggaccgccccccggaucggc
gaccggccgccgccgggcgcacuuccaggcggugcgccgcgaccggcucc
gggacggcugggaaggcccggcggggaagguggcucggggccccgagugu
uacagccccccggcagcagcgcucgccgaaucccggggccgagggagccg
gauacccgucgccgcgcucuccccccggcgggggccgggccgccccuccc
acggcgcgaccgcucucccagggggcggggcggacuguccccagugcgcc
ccgggcgucgucgcgccgucgggcccgggcgcgcucucccuccccuucuc
ggggugggggggagcgagagcgcacggggucggcggcgaugucggcuacc
cacccgacccgucuugaaacacggaccaaggagucuaacgcgugcgcgag
ucaggggcucguccgaaagccgccguggcgcaaugaaggugaagggcccc
guucccgggggccgaggugggaucccgaggccucuccaguccgccgaggg
gcaccaccggcccgucucgcccgccgcgccggggagguggagcacgagcg
uacgcguuaggacccgaaagauggugaacuaugccugggcagggcgaagc
cagaggaaacucugguggagguccguagcgguccugacgugcaaaucggu
cguccgaccuggguauaggggcgaaagacuaaucgaaccaucuaguagcu
gguucccuccgaaguuucccucaggauagcuggcgcucucgcaacgcggu
cgacaacccgcaguuuuauccgguaaagcgaaugauuagaggucuugggg
ccgaaacgaucucaaccuauucucaaacuuuaaauggguaagaagcccgg
cucgcuggcguggagccgggcguggaaugcgagugccuagugggccacuu
uugguaagcagaacuggcgcugcgggaugaaccgaacgccggguuaaggc
gcccgaugccgacgcucaucagaccccagaaaagguguugguugauauag
acagcaggacgguggccauggaagucggaauccgcuaggaguguguaaca
acucaccugccgaaucaacuagcccugaaaauggauggcgcuggagcguc
gggcccauacccggccgucgccggcgucggaacgggacgggagcggccgc
ucgggccccgcggacgcuacgccgcgacgaguaggagggccgcugcggug
agccuugaagccuagggcgcgggcccggguggagccgccgcaggugcaga
ucuuggugguaguagcaaauauucaaacgagaacuuugaaggccgaagug
gagaaggguuccaugugaacagcaguugaacaugggucagucgguccuga
gagaugggcgagugccguuccgaagggacgggcgauggccuccguugccc
ucagccgaucgaaagggagucggguucagauccccgaauccggaguggcg
gagaugggcgccgcgaggcguccagugcgguaacgcgaccgaucccggag
aagccggcgggagccccggggagaguucucuuuucuuugugaagggcagg
gcgcccuggaauggguucgccccgagagaggggcccgugccuuggaaagc
gucgcaguuccggcggcguccggugagcucucgcuggcccuugaaaaucc
gggggagaggguguaaaucucgcgccgggccguacccauauccgcagcag
gucuccaaggugaacagccucuggcauguuggaacaauguagguaaggga
agucggcaagccggauccguaacuucgggauaaggauuggcucuaagggc
uggcagccgacuuagaacuggugcggaccaggggaauccgacuguuuaau
uaaaacaaagcaucgcgaaggcccgcggcggguguugacgcgaugugauu
ucugcccagugcucugaaugucaaagugaagaaauucaaugaagcgcggg
uaaacggcgggaguaacuaugacucucuuaagguagccaaaugccucguc
aucuaauuagugacgcgcaugaauggaugaacgagauucccacugucccu
accuacuauccagcgaaaccacagccaagggaacgggcuuggcggaauca
gcggggaaagaagacccuguugagcuugacucuagucuggcacggugaag
agacaugagagguguagaauaagugggaggcccgggccgccggugaaaua
ccacuacucucaucguuuuuucacugacccggugaggcgggggggcgagc
cccgaggggcucucgcuucuggcgccaagcgcccgucgggcgggcgcgac
ccgcuccggggacagugccagguggggaguuugacuggggcgguacaccu
gucaaacgguaacgcagguguccuaaggcgagcucagggaggacagaaac
cucccguggagcagaagggcaaaagcucgcuugaucuugauuuucaguac
gaauacagaccgugaaagcggggccucacgauccuucugaccuuuugggu
uuuaagcaggaggugucagaaaaguuaccacagggauaacuggcuugugg
cggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggcuc
uuccuaucauugugaagcagaauucaccaagcguuggauuguucacccac
uaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuuu
acccuacugaugauguguuguugccaugguaauccugcucaguacgagag
gaaccgcagguucagacauuugguguaugugcuuggcugaggagccaaug
gggcgaagcuaccaucugugggauuaugacugaacgccucuaagucagaa
ucccgcccaggcggaacgauacggcagcgccgaaggagccucgguuggcc
ccggauagccggcucccgggguccggugcggagagccauucgucccggga
aacggggugcggccggaaagggggccgcccucucgcccgucacgcuuaac
gcacguucguguggaaccuggcgcuaaaccauucguagacgaccugcuuc
ugggucgggguuucguacguagcagagcagcucccucgcugcgaucuauu
gaaagucagcccucgacacaaggguuugu
.........................<<<<<<.....<......>......
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.......>.>..................................>>>>..
>>>>..>....>>..>>.>.......<<<<<<<........>>>>>>>..
...(((((..<<<<<<)))))..]]]........................
..........<<....>>...............<<<<....>>>>.....
.............................<<<<<<<<..<<<.<.....<
..<<.<..<.<....<<.<..<..<.........<.<..<<<..<<..<<
<<<.<<<..<<<<<<<.....>..>>>>>>>>>>>>>>>>.>>>.>.>..
......>..>..>.>>....>.>..>.>>..>..<<<<<<<..<<<<<<<
<<<.<<<....<..<.......<<.<......<<<<<<<..>>>>>>>..
.......>>>......>......>.>>>...>>>>>>>>>>.........
.................<..<<<<<....>>>>>..<.<<.<.<<<.<<.
..<....<..<<<<...<<...>>..<<<<<<.<<<<....>>>>.>>>>
>>.>>>>...>....>....>>....>>>>>>..>.......<<<<<<<.
.....>>>>>>>.......>..........>>.>>>>>...>>>>...>>
>>>>>>..<<<<........>>>><<<<<<....<<<<<<<<<<<<<..<
<<...<<<<........>>>>.....>>>...<<....>>...<<.<<<<
<....>>>>>.>>..<<<<<..<<<...<....((((..[[..>...>>>
...>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>>>.>>....>>>
>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<
<<<<<....>>>>>>>.....>>>...<<<..<<.<<........>>>>.
>>>....>>>>>>>>>...<<.......>>......>>>>>>...>..>.
>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<..........<<
..>>.....<<<.<<<<<<<<<...<<<....<<<..<.<<<..<<<<<<
.........>>>>>>>>>.>..>>>..>.>>...>>>>>>>...<<<<<<
<<<.<......>>>>>>>>>>....>>>>>>>>>>>>.>>>..<<<<.<<
<<<.....>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<
(((.......<<<<<.....<<..........<<<.<<<<<<<<<<....
...<<<<<.<<.....................>>........<.......
.>...>>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>
..>>>...>>>>>>><<<<<<.<...........]]...)))).......
.....................>.>>>>>>....>>>>>>.<.<<<<<<<<
.<<......<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>....
.>>>>>><<.....<<.....<<<<<<.......>>>>>>.<<<.....<
<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...
<<....<<<....>>>..........<<.<<<<<<<<<...>>>>>>>>>
>>......>>....>>>..<<<<<........>>>>>))<<<<....<<<
<<..<<<<<<<<....>>>>>>>>..<<<....>>>...<..<<<<<<<.
..<<<<<<<<<<<<<<<<<<<<<<<..{{{..>>>>>>....<<<<<.<<
<<.<<<<.....<<<.....>>>.....>>>>>>>>..>>>>>.....<<
<<<<<.......>>>>>>>>>>>.>.>>>>>>>>>>>>.........>>>
>>>>..>..........>>.>>>.>>>>.>>>..>>.....<<......>
>>>>>>.<<<<.....>>>>..>>>....<<<<.....<<<<<<<.<<..
.............<<<<<....<<..>>.....>>>>><<.<<<<<<<<<
<<.>>>>>..>>>>>>.>>............<<<<<<<<<..<<<.....
....>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>...<
<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>.>>>
>..>>>>><<<<<<.......>>>>>>........<...........<<<
<<.......>>>>>.....>.....>>....>>.>>>>>>>.....>>.>
>>>>>>..>>>>>>....>>....<<<<<........>>>>>....[[[[
[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<
<<<<<<<<<<<..........<<<.<..<<<<..>>>>............
>.>>>.>>>>>>>.>>>>>>>>>>...<<<<<.....<<<<....<<<..
.<.....>..>>..>.............<<<<<<<<...>>>>>>>>..>
>>>..>>>>>....>>>>>>>>>..>>>>>...<<<.....>>>..<<<<
<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......>
>>>>>.....<<...(((>>....>>>>>>>...<<<..<<<<.......
>>>>..>>>.<<<....>>>.>>))).......((((((..(((..>>>>
>>.)))))))))..........]]]]..}}]]]].......<<.<.<.<<
<<<<...<<.......>>...>>>>>>...>>.>.>.......<<<<<.<
<<<<<..<.<.<<<<<......>>>>>...>.>.<<<.........>>>.
....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}}
..}}}.]]]]].....<<<<<<.<..<<<..<.<<<<<............
.....>>>>>.><<<<....<<<<....<<.<<<<<<<}}}.>>>>>..>
>.>>...>>>>...>>>><<<<....<<<<<...........>>>>>...
.>>>>.>>>...>.>>>>>>......<<<<<...<...<.<.<<......
..........<.<<<..>>>.>..................<<<..<<<<.
........<<<<<..........>>>>>.......>>>>..>>>......
......>>..>.>...>..>>>>>.<<<<<.<.............>....
.<.<<<<<<<.<<.....<<<<.<..<<<<<......>>>>>..>>>>>.
...>>....>>>>.>>>.>...>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qgg Neuronal RNA granules are ribosome complexes stalled at the pre-translocation state.
Resolution2.86 Å
Binding residue
(original residue number in PDB)
R11 C13 K19 N21 R35 N36 S37 F38 R39 R46 R66 R67 S68 K84 N85 R87 S92 R94 H95 R98 K99 N100 R107 M108 R112 R132
Binding residue
(residue number reindexed from 1)
R10 C12 K18 N20 R34 N35 S36 F37 R38 R45 R65 R66 S67 K83 N84 R86 S91 R93 H94 R97 K98 N99 R106 M107 R111 R131
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7qgg, PDBe:7qgg, PDBj:7qgg
PDBsum7qgg
PubMed36038000
UniProtF7EPV5

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