Structure of PDB 7nhm Chain r Binding Site BS01

Receptor Information
>7nhm Chain r (length=79) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDRKVYVGKVVSDKMDKTITVLVETYKTHKLYGKRVKYSKKYKTHDENNS
AKLGDIVKIQETRPLSATKRFRLVEIVEE
Ligand information
>7nhm Chain a (length=1531) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauaca
ugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggcg
gacgggugaguaacacguggauaaccuaccuauaagacugggauaacuuc
gggaaaccguagcuaauaccggauaauauuuugaaccgcaugguucaaaa
gugaaagacggucuugcugucacuuauagauggauccgcgcugcauuagc
uaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccuga
gagggugaucggccacacuggaacugagacacgguccagacuccuacggg
aggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaac
gccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggga
agaacauauguguaaguaacugugcacaucuugacgguaccuaaucagaa
agccacggcuaacuacgugccagcagccgcgguaauacguagguggcaag
cguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaagu
cugaugugaaagcccacggcucaaccguggagggucauuggaaacuggaa
aacuugagugcagaagaggaaaguggaauuccauguguagcggugaaaug
cgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugua
acugacgcugaugugcgaaagcguggggaucaaacaggauuagauacccu
gguaguccacgccguaaacgaugagugcuaaguguuagggggccccuuag
ugcugcagcuaacgcauuaagcacuccgccuggggaguacgaccgcaagg
uugaaacucaaaggaauugacggggacccgcacaagcgguggagcaugug
guuuaauucgaagcaacgcgaagaaccuuaccaaaucuugacauccuuug
acaacucuagagauagagccuuccggacaaagugacagguggugcauggu
ugucgucagcucgugucgugagauguuggguuaagucccgcaacgagcgc
aacccuuaagcuuaguugccaucauuaaguugggcacucuaaguugacug
ccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcccc
uuaugauuugggcuacacacgugcuacaauggacaauacaaagggcagcg
aaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauugu
agucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagauca
gcaugcuacggugaauacguucccgggucuuguacacaccgcccgucaca
ccacgagaguuuguaacacccgaagccgguggaguaaccuuuuaggagcu
agccgucgaaggugggacaaaugauuggggugaagucguaacaagguagc
cguaucggaaggugcggcuggaucaccuccu
...<<<<....((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<........................>>>.>>>>>.
.....<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<.<
<<....>>>.>>......>>>>......<<<<<<<<<....>>>>>>>>>
......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<
<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<..
..>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>
>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>
>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<..
.....<.<<<<<<..........>>>>>>.>........>>>>>>...>.
.<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..>
>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<<
<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>>
>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......>>
>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>>.
>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>>
>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>>>
>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>
>>....>>>..))))..<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<
<<......<<........>>..........<<<<<<<......<<<<<<.
....<<<<<....>>>>>..........>>>>.>>.<<<.<<<..<<<<<
<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>..
...<<<<.<<<<<<<..<<..<<<......>>>>>...>>>>>>>.....
<<<<<.....>>>>>........>>>>.........>>>...>>>>>>>>
>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<.
..<<<....>>>...>>....>>>.....>>>>>>>......<....<<<
<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<....
.....>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<
<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>>>
.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<<<
<<<<<<....>>>>>>>>>............
Receptor-Ligand Complex Structure
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PDB7nhm Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		N5 R7 K8 Y10 S16 K18 M19 D20 K21 K31 K34 L35 Y36 R39 K41 Y42 S43 K44 K45 Y46 K47 T66 R67 P68 L69 S70 A71 T72 K73 R74 R76
Binding residue
(residue number reindexed from 1)		N1 R3 K4 Y6 S12 K14 M15 D16 K17 K27 K30 L31 Y32 R35 K37 Y38 S39 K40 K41 Y42 K43 T62 R63 P64 L65 S66 A67 T68 K69 R70 R72
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7nhm, PDBe:7nhm, PDBj:7nhm
PDBsum7nhm
PubMed34117249
UniProtQ2FW15|RS17_STAA8 Small ribosomal subunit protein uS17 (Gene Name=rpsQ)

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