Structure of PDB 6bk8 Chain r Binding Site BS01

Receptor Information

>6bk8 Chain r (length=84) Species: 559292 (Saccharomyces cerevisiae S288C)

NTLYVSQLNEKINMQRLRVNLFLLFATFGEVLKVSMNFKKQRGQAFITMR
TIDQASLAQISLNGERFFGKPLKVEFSKSETKTL

Ligand information

>6bk8 Chain 2 (length=135)

gaaucucuuugccuuuuggcuuagaucaaguguaguaucuguucuguaac
aacuguuguuacggacgggaagaggagacgucgcgacccucgcagucguu
cuugacuggucgcuugauguuucuucuucccguuc

.............................................<<<<<
<<...>>>>>>><<<<<<<<<<<.<<<<<<<<<<<<.<<.....<<<<..
..>>>>.>>>>>>..>>>>>>>>.>>>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6bk8 Structure of the yeast spliceosomal postcatalytic P complex.
• Resolution: 3.3 Å
• Binding residue (original residue number in PDB): Y31 M41 Q68 R69 F73 S104 T108
• Binding residue (residue number reindexed from 1): Y4 M14 Q41 R42 F46 S77 T81

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0030620 U2 snRNA binding

Biological Process

• GO:0000398 mRNA splicing, via spliceosome
• GO:0006397 mRNA processing
• GO:0008380 RNA splicing
• GO:1903241 U2-type prespliceosome assembly

Cellular Component

• GO:0005634 nucleus
• GO:0005681 spliceosomal complex
• GO:0005686 U2 snRNP
• GO:0071004 U2-type prespliceosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6bk8, PDBe:6bk8, PDBj:6bk8
• PDBsum: 6bk8
• PubMed: 29146870
• UniProt: P40567|MSL1_YEAST U2 small nuclear ribonucleoprotein B'' (Gene Name=MSL1)