Structure of PDB 8ipb Chain qa Binding Site BS01

Receptor Information
>8ipb Chain qa (length=119) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRVRTKTVKKTSRQVIEKYYSRMTLDFHTNKKVLEEVSILQSKRLRNKVA
GFTTHLMRRIQRGPVRGISLKLQEEERERRMDFVPEKSALEVDEIRVDKE
TMDMLAFLGMADLPGVERA
Ligand information
>8ipb Chain aa (length=1695) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaauccgaugauucaugauaacucgacggaucgcacg
gccuucgugccggcgacgcaucauucaaauuucugcccuaucaacuuucg
augguaggauaggggccuaccaugguggugacgggugacggagaauuagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccaauccugacacggggagguagugacaau
aaauaacaauaccgggcgcauuagugucugguaauuggaaugaguacaau
cuaaaucccuuaacgaggauccauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuuaaguuguugcaguuaaaa
agcucguaguuggaccuugggccggccggcaucgcgcuccuagcccggca
ucguuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggau
acauuagcaugggauaacaucauaggauuccgguccuauuguguuggccu
ucgggaucggaguaaugauuaauagggacagucgggggcauucguauuuc
auagucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaa
gcauuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucg
aagacgaucagauaccguccuagucucaaccauaaacgaugccgaccagg
gaucggcggauguugcuuauaggacuccgccggcaccuuaugagaaauca
aagucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggcguggagccugcgcuuaauuugacuc
aacacggggaaacuuaccagguccagacauagcaaggauugacagacuga
gagcucuuucuugauucuaugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccguuaacgaacgagaccucagccugc
uaacuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacu
auggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcc
cuuagauguucugggccgcacgcgcgcuacacugauguauucaacgagua
uauagccuuggccgacaggcccggguaaucuugggaaauuucaucgugau
ggggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaag
cgcgagucaucagcucgcguugacuacgucccugcccuuuguacacaccg
cccgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggc
gacggacgucgcgagaaguccauugaaccuuaucauuuagaggaagcaga
agucguaacaagguuuccguaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<.............<.....<..<
<<.....>>>..>......>...........<<<..<<....>>..>>>.
<...<<<<<<..................>>>>>>.....>...<<<<.<<
<<......>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>....>.
>.....<<<<<.<<..............>>.>>.>>>......<<..<..
.........>..>>.........<<<<<((......<<<<.....<<..)
)>>.......>>>>.>>>>>..>>>>>>>>>..........<.<((....
.<.<<...<<<.<<....<.<<<<..>>>>.>..................
..<<<<<<.<<.......<<...<.......>...<.......>.....>
>......>>.>>..>>>>........<<..<<<<<<<.............
..>>>>>>>..>>.....>>....<<<<<<.<<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<.<<<.<.....>>>>>>>>>>>>..>>>...<<..))>>.
..>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<....
....>>..........<<<<<.<....<<<<<........<<.<<<....
....>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<
<<<..<<...<<<<<<<......>>>>>>>.....>>..>>>>.>>....
.<<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<..
.....<<<.<<<<....>>>>.>>>....>>........>.>>>>.....
......<<<<<<..........>>>>>>..........>>>>>>....<<
<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<
..<<.<.<<.<<.<<....<<<<<<<..<<<..<<<<..<...<<<...<
.......>...>>>...>..>>>>..>>>..>>>>>>>...>>.>>.>>.
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB8ipb Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
G2 R3 V4 R5 K7 T8 K10 F28 K32 S43 K44 R45 N48 K49 G52 R59 R60
Binding residue
(residue number reindexed from 1)
G1 R2 V3 R4 K6 T7 K9 F27 K31 S42 K43 R44 N47 K48 G51 R58 R59
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ipb, PDBe:8ipb, PDBj:8ipb
PDBsum8ipb
PubMed38267667
UniProtA0A3B5YWZ3

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