Structure of PDB 7obq Chain q Binding Site BS01

Receptor Information

>7obq Chain q (length=104) Species: 9615 (Canis lupus familiaris)

RFICIYPAYLNNKKTIAEGRRIPISKAVENPTATEIQDVCSAVGLNVFLE
KNKMYSREWNRDVQYRGRVRVQLKQEDGSLCLVQFPSRKSVMLYAAEMIP
KLKT

Ligand information

>7obq Chain 1 (length=165)

cuaugccgaucggguguccgcacuaaguucggcaucaauauggugaccuc
ccgggagcgggggaccaccagguugccuaaggaggggugaaccggcccag
gucggaaacggagcaggucaaaacucccgugcugaucaguagugggaucg
cgccugugaauagca

.<.........<<<<<<<<.<<<<<.<.<<<<<<<<<<<.<<<<<..<<<
<<<....>>>>>>..>>>>>.>>>>........<<<<<.....<<<<..<
.<<<....>>>..>.>>>>...>>>>>.>>>>>>>.>..>>>>>>>...>
>>>>>.......>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7obq Molecular mechanism of cargo recognition and handover by the mammalian signal recognition particle.
• Resolution: 3.9 Å
• Binding residue (original residue number in PDB): R14 F15 I16 C17 Y19 Y22 T28 I29 R33 P36 I37 K66 M67 S69 R70 R81 R101
• Binding residue (residue number reindexed from 1): R1 F2 I3 C4 Y6 Y9 T15 I16 R20 P23 I24 K53 M54 S56 R57 R68 R88

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0008312 7S RNA binding

Biological Process

• GO:0006614 SRP-dependent cotranslational protein targeting to membrane
• GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

Cellular Component

• GO:0005634 nucleus
• GO:0005654 nucleoplasm
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005786 signal recognition particle, endoplasmic reticulum targeting
• GO:0048500 signal recognition particle

External links

• PDB: RCSB:7obq, PDBe:7obq, PDBj:7obq
• PDBsum: 7obq
• PubMed: 34260909
• UniProt: J9PAS6|SRP19_CANLF Signal recognition particle 19 kDa protein (Gene Name=SRP19)