Structure of PDB 7a5j Chain q Binding Site BS01

Receptor Information
>7a5j Chain q (length=128) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YRARPPPRRRPGPRWPDPEDLLTPRWQLGPRYAAKQFARYGAASGVVPGS
LWPSPEQLRELEAEEREWYPSLATMQESLRVKQLAEEQKRREREQHIAEC
MAKMPQMIVNWQQQQRENWEKAQADKER
Ligand information
>7a5j Chain A (length=1492) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccccaccuuacuaccaaaccuuagccaaacc
auuuacauaaaguauaggcgauagaaauugggcgcaauagauauaguacc
gcaagggaaagaugaaaaaaccaagcauaauauagcaaggacuaaccccu
auaccuucugcauaaugaauuaacuagaaauaacuuugcaaggagagcca
aagcuaagacccccgaaaccagacgagcuaccuaagaacagcuaagagca
cacccgucuauguagcaaaauagugggaagauuuauagguagaggcgaca
aaccuaccgagccuggugauagcugguuguccaagauagaaucuuaguuc
aacuuuaaauuugcccacagaaccaaauccccuuguaaauuuaacuguua
guccaaagaggaacagcucuuuggacacuaggaaaaaaccuuguagagag
aguaaaaaauuuaacacccauaguaggccuaaaagcagccaccaauuaag
aaagcguucaagcucaacacaaaaaucccaaacauauaacugaacuccuc
acacccaauuggaccaaucuaucacccuauagaagaacuaauguuaguau
aaguaacaugaaaacauucuccuccgcauaagccugcgucagcaacugac
aauuaacagcccaauaucuacaaucaaccaacaagucauuauuacccuca
cugucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaa
aggaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucua
gcaucaccaguauuagaggcaccgccugcccagugacacauguuuaacgg
ccgcgguacccuaaccgugcaaagguagcauaaucacuuguuccuuaaau
agggaccuguaugaauggcuccacgaggguucagcugucucuuacuuuua
accagugaaauugaccugcccgugaagaggcgggcauaacacagcaagac
gagaagacccuauggagcuuuaauuuauuaaugcaaacaguaccuaacaa
acccacagguccuaaacuaccaaaccugcauuaaaaauuucgguuggggc
gaccucggagcagaacccaaccuccgagcaguacaugcuaagacuucacc
agucaaagcgaaccucaauugauccaauaacuugaccaacggaacaaguu
acccuagggauaacagcgcaauccuauucuagaguccauaucaacaauag
gguuuacgaccucgauguuggaucaggacaucccgauggugcagccgcua
uuaaagguucguuuguucaacgauuaaaguccuacgugaucugaguucag
accggaguaauccaggucgguuucuaucuacuuuauuccucccuguacga
aaggacaagagaaauaaggccuacuucacaaagcgccuucccccguaaau
gauaucaucucaacuuagauacccacacccaagaacaggguu
<<<.......<<<<...............................<....
..>...........<<.....>>.......>>.>>.............<<
....>>.................>>>...........<<<.......>>>
...<.<........>.>.<<<<<<.........<<<.<<..<<....>>.
..>>.>>>...<<.<...<<<<.<.....<<<<<.<<<..<<<...>>>.
..<<<..<<<<........>>>>.>>>....>>>.>>>>>...<<.....
..>>......>.>>>>......>.>>..<<<<<<....<<<<....>>>>
<<<.<<<<<<<<<<.....<<......>>.....>>>>>>>>>>..>>>.
<<<<<<<<<<......>>>>>>>>>>...<<<......>>>....<<<.<
<<...<..............<....<<<.........>>>....>.....
..<<<......>>>..........................>...>>>>>>
........>>>>>>...<<<<<......>>>>>.........>>>>>>..
.....<<..<<<....>>><<<<..<<<<........<<<<<...>>>>>
......<<<...<<<<.......................>>>>.......
>>>.....<<......>>.>>>>.....>>>>..<<<<...<<<<<<<<.
<<.........<......<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>....<<<.<<<..<<<<<....>>>..>>>>
>...<<........>>...........<...........<<<<<<.....
>>>>>>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>
>>>.>>...........<<<<<........>>>>>.......<<..<<<.
<<......<<<<.<<<<<<..<<<<<.<<<<<<<<...............
<<<....>>>................>>>>>>>>>>>>>..<<<<.....
>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<.....
>>>>..>>>....>>...........<....>..............>>>>
..>>>>>>.......<<<..<.<<<<<<...<<.......>>...>>>>>
>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<......>>>>
>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<
<<<<<<....>>>.>>>>....>>..>>>.>>..<<<.<<<.........
........>>>.>>><<<<<...<<<....>>>.>>>>>......<<<..
..............>>>.........<<<<.......>>>>.
Receptor-Ligand Complex Structure
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PDB7a5j Elongational stalling activates mitoribosome-associated quality control.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R55 K59
Binding residue
(residue number reindexed from 1)		R31 K35
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7a5j, PDBe:7a5j, PDBj:7a5j
PDBsum7a5j
PubMed33243891
UniProtQ8TAE8|G45IP_HUMAN Large ribosomal subunit protein mL64 (Gene Name=GADD45GIP1)

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