Structure of PDB 6zs9 Chain q Binding Site BS01

Receptor Information

>6zs9 Chain q (length=164) Species: 9606 (Homo sapiens)

YRARPPPRRRPGPRWPDPEDLLTPRWQLGPRYAAKQFARYGAASGVVPGS
LWPSPEQLRELEAEEREWYPSLATMQESLRVKQLAEEQKRREREQHIAEC
MAKMPQMIVNWQQQQRENWEKAQADKERRARLQAEAQELLGYQVDPRSAR
FQELLQDLEKKERK

Ligand information

>6zs9 Chain XA (length=1501)

gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccaa
aauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuugga
cacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauagua
ggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccaaaa
aucccaaacauauaacugaacuccucacacccaauuggaccaaucuauca
cccuauagaagaacuaauguuaguauaaguaacaugaaaacauucuccuc
cgcauaagccugcgucagauaaccaacugacaauuaacagcccaauaucu
acaaucaaccaacaagucauuauuacccucacugucaacccaacacaggc
augcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuua
ccccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagagg
caccgccugcccagugacacauguuuaacggccgcgguacccuaaccgug
caaagguagcauaaucacuuguuccuuaaauagggaccuguaugaauggc
uccacgaggguucagcugucucuuacuuuuaaccagugaaauugaccugc
ccgugaagaggcgggcauaacacagcaagacgagaagacccuauggagcu
uuaauuuauuaaugcaaacaguaaccaaaccugcauuaaaaauuucgguu
ggggcgaccucggagcagaacccaaccuccgagcaguacaugcuaagacu
ucaccagucaaagcgaaccucaauugauccaauaacuugaccaacggaac
aaguuacccuagggauaacagcgcaauccuauucuagaguccauaucaac
aauaggguuuacgaccucgauguuggaucaggacaucccgauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggaguaauccaggucgguuucuaucuacuuauuccucccugu
acgaaaggacaagagaaauaaggccuacuucacaaagcgccuucccccgu
aaaugauaucaucucaacuuagaauacccacacccacccaagaacagggu
u

<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
..>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>>>
>...<<<......>>>....<<<.<<<...<..............<....
<<<.........>>>....>.......<<<......>>>...........
................>...>>>>>>........>>>>>>...<<<<<..
....>>>>>.........>>>>>><......<<..<<<....>>><<<<.
.<<<<........<<<<<........>>>>>......<<<...<<<<...
....................>>>>.......>>>.....<<......>>.
>>>>.....>>>>..<<<<...<<<<<<<<.<<.........<......<
<<<<<..<<<.........>>>...<<<<<<.............>>>>>>
....<<<.<<<..<<<<<....>>>..>>>>><<<<<<......>>>>>>
........<...........<<<<<<.....>>>>>>.....>....>>>
....>>.>>>>.....>..>>.>>>>>>>>>>>>.>>.....>.....<<
<<<........>>>>>.......<<..<<<.<<......<<<<.<<<<<<
..<<<<<.<<<<<<<<...............>>>>>>>>>>>>>..<<<<
.....>>>><<<<<<...........>>>>>>..<<.....<<<..<<<<
.....>>>>..>>>....>>.........<<<....>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<.......>>>>.....>>>>>..>...>>>.>>
....<<<<<<<....>>>.>>>>....>>..>>>.>>.<<<.<<<.....
............>>>.>>><<<<<...<<<....>>>.>>>>>......<
<<................>>>..............<<<<.......>>>>
.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6zs9 Structural basis of mitochondrial translation.
• Resolution: 4.0 Å
• Binding residue (original residue number in PDB): R34 R38 R49 W50 R55 K59
• Binding residue (residue number reindexed from 1): R10 R14 R25 W26 R31 K35

Gene Ontology

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:6zs9, PDBe:6zs9, PDBj:6zs9
• PDBsum: 6zs9
• PubMed: 32812867
• UniProt: Q8TAE8|G45IP_HUMAN Large ribosomal subunit protein mL64 (Gene Name=GADD45GIP1)