Structure of PDB 7oya Chain p1 Binding Site BS01

Receptor Information
>7oya Chain p1 (length=91) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRTKKVGIVGKYGTRYGASLRKMVKKIEISQHAKYTCSFCGKTKMKRKA
VGIWHCGSCMKTVAGGAWSYNTTSAVTVKSAIKRLKELKDQ
Ligand information
>7oya Chain 51 (length=3321) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cacgaccucagcucagacgagaagacccgcugaauuuaagcauauuacua
agcggaggaaaagaaaccaaccgggauucccccaguagcggcgagcgaag
agggaaaaguccagcgccgaauccccgccccagggcgagggaccuguggc
guacggagggccgccucucucggcgcgggggccaaaguccuucugaugga
ggcuuagcccgcggacggugugaggccggugucggcccccgccccgccgg
ggugcgguuccucccggagucggguuguuugggaaugcagcccaaagcgg
gugguaaacuccaucuaaggcuaaauaccggcacgagaccgauagcggac
aaguaccgugagggaaaguugaaaagaacuuugaagagagaguucaacag
ggcgugaaaccguuaagagguaaacggguggggaccgcaccguccgcccg
guggauucagcccggcggggcggggucggcccguccgguggcucccuucg
cucccgcgggggguugacgcccgggcgaaggcucggccgccgccgggugc
auuuccgccgcgguggagcgccgcgaccggcuccgguucggcuuggaagg
gucagggggcgaagguuuuacagcgcccucccgccccgacuucgccgcuu
gcucuccggggccgcgggcccucucugcccucccucugcggggacggggu
cccccgcccccggcguggcgcgacagggguggacuguccucaguccgcug
cgccgcgccgcccagggcgggggacccacguucgggcgcccgagguccgc
ggcgacgccggccucccacccgacccgucuugaaacacggaccaaggagu
ccaacgcgcgcgcgagucagaggguggcucgcgagccccugcggcgcaau
gaaggugagggugggauccccccgccccggcggggggcgcaccaccggcc
cgccucgcgacccuccggggggcagguggaguuggagcgcgcgcgauggc
acccgaaagauggugaacuaugccugggcagggcgaagccaggggaaacu
cugguggaggcccgccgcgguccugacgugcaaaucggucguccgaccug
ggcauaggggcgaaagacuaaucgaaccaucuaguagcugguucccuccg
aaguuucccucaggauagcuggcgcucgccgaucaagcaguuuuauccgg
uaaagccaaugacuagaggcaccuauucucaaacuuuaaauggguaagag
gcccggcucgcuggcgcuggagccgggcguggaaugcgacgcgccuagug
ggccauuuuugguaagcagaacuggugcugcgggaugaaccgaacgccgg
guuaaggcgcccgaugccgacgcucaucagaccccauaaaagguguuggu
ugauauagacagcccgaaucaacuagcccugaaaauggauggcgcuggag
cgucgggcccauacccggccgucgacggcagcugcaagccucgacgagua
ggagggccgccgcgguggcgccgaagcccagggcgcgggcccggguggag
ccgccgcgggcgcagaucuuggugguaguagcaaauauucaaacgagagc
uuugaaggccgaaguggagaaggguuccaugugaacagcaguugaacaug
ggugagccgguccuaagggacgggccuacgccguucggaggggagggccc
cgcucgaccgaaagggagucggguccagauccccgagcccggagcggcgg
agacgggcgccgcgaggcgcccagugcggugacgcaaacgaacccggaga
ugccggcgggugccccgggaaagaguucucuuuucuuugugaagggcagg
gcgcccuggaacggguucgccccgagagaggggcccgcgcccuggaaagc
gccgcgcuucuggcggcguccggugagcucucgucggcccuugaaaaucc
gggggagaagguguaaaucucgcgccgggccguacccauauccgcagcag
gucuccaaggugaacagccucuggcguguuggaacaaggcagaguaaggg
aagucggcaagucagauccguaacuucgggauaaggauuggcucuaaggg
cugauagcagccagcuuagaacugucgcggaccaggggaauccgacuguu
uaauuaaaacaaagcaucgcgaaggcccucggcggguguugacgcgaugu
gauuucugcccagugcucugaaugucaaagugaagaaauucaacgaagcg
cggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugccu
cgucaucuaauuagugacgcgcaugaauggaugaacgagauucccacugu
cccuaccugcuaucuagcgaaaccacagccaagggaacgggcuuggcaga
aucagcggggaaagaagacccuguugagcuugacucuagucuggcccugu
gaagagacuuuccucacuuacccggugaggcgggcuucuggcgucaagcg
ccccgcggggcgcgacccgccccggggacagcgucagguggggaguuuga
cuggggcgguacaccugucaaacgguaacgcagguguccuaaggcgagcu
caggggggacagaaaccucccguagagcagaagggcaaaagcucgcuuga
ucuugauuuucaguaugaguacggaccgcgaaagcggggccucacgaucc
uuccggcuuuugggguuuuaagcgggaggugucagaaaaguuaccacagg
gauaacuggcuuguggcggccaagcguucauagcgacgucgcuuuuugau
ccuucgaugucggcucuuccuaucauugugaagcagaauucaccaagcgu
uggauuguucacccacuaacagggaacgugagcuggguuuagaccgucgu
gagacagguuaguuuuacccuacugaugugagccguuguugcaauaguaa
ucccgcucaguacgagaggaaccgcggguucagacauuugguucgugcgc
uuggcugaggagccacuggcgcgaagccaccaucugcgggauuaugacug
aacgccucuaagucagaaucccgccuaaaagcaacgauaagcgccgucgg
aucuccgauaggccccggguaaccgggaccccggcgcggagagccauucg
ugacaggagcggcuagaacgagcgccgcccccucuuccagugacgcaccg
cauguuuguggggaacccggugcuuaaaugacucguagacgaccugauuc
ugggucggggugucgugcguggcagagcagcgcugcgauccauugaaagu
cagcccucgauccaaguuuug
.........................<<<<<<.....<......>......
>>>>>.>.........<<....>>..<<<<<......<<.....>>....
.>>>>>..<<<..<<<<<...<<<<<<<<<..>>>>>.>>>>.....>>>
>>..<<<<<<<<<<...<<<.<..<.<<<<<<<.....<<<<......>>
>>.....((......<<<.....))>>>.....>>>>>>>...>..>.>>
>..>>>>>.>>>>>.......<<<<<<<........>>>>>>>.....<<
<<<..((((((>>>>>..>>>.............................
.....<<....>>...............<<<<....>>>>..........
........................<<<<<<<<..<<<.......<<<<..
.<<<<....<<<<<<<<<.......<.<.<.<<<<.<..........<..
<.......>..>........>..>>>>..>..>.>....>>>>>>>>>..
...>>>>....>>>>.....<...<.<.<.<<<.<<...<....<<..<<
...<<<<.<<....<.>.....>>.>>>>....>>.........>>.>..
...>>..>>>.>.>........<.<<...<<<<.<..>.>>>>...<<<<
<..<<.<.<.<<<<<<...<<<<......<<<<<<<....>>>>>>>.>.
>>>.>>>>>>......>.>.>>>>>>>.......>>.>.......>....
>.......>>>...>>>>>>>>..<<<<........>>>><<<<<<....
<<<.<<<<<<<<<..<<<...<<<<.........>>>>....>>>...<<
....>>...<<<<<...<<<<<<<<....>>>>>>>>....>>>>><<<<
<<<<<.....<........>...>>>>>>.>>>...>>>>>>>>>.>>>.
.<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>
>>>>>.....>>>...<<<..<<.<<........>>>>.>>>....>>>>
>>>>>...<<.......>>......>>>>>>...>..>.>>..<<<<<<.
...<.<<<....>>>.><<.<<<<<<<.........<<<.<<<<<<<<<.
..<<<....<<<....<<<..>>>....>>>..>.>>...>>>>>>>...
<<<<<<<<<..........>>>>>>>>>....>>>>>>>.>>>>>..>>.
.<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<<<<
<<...<<<(((.......<<<<<.....<<..........<<<.<<<<<<
<<<<.......<.>...>>>>>>>>>>>>>..........))).>>...>
>>>>..>>>...>>>>>>><<<<<<.<<<........>>>>>>>>>....
>>>>>>.<.<<<<<<<<<<......<<<<.<<<<....>>>>>>>>...>
>>>>>>>>>..>.....>>>>>><<.....<<.....<<<<<<.......
>>>>>>.<<<.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>
>....((<<<<<<...<<....<<<....>>>............<...>.
.......>>....>>>..<<<<<........>>>>>))<<<<....<<<<
....<<<<<<<....>>>>>>>...<<<....>>>...<...<<<<<<..
.<<<<<<<<<.<<<<<<<.<<<<<<..[[[..>>>>>>....<<<<<.<<
<<.<<<<.....<<<.....>>>.....>>>>>>>>..>>>>>.....<<
<<<<<.......>>>>>>>>>>>.>.>>.>>>>>>>>>.........>>>
>>>...>..........>..>>>.>>>>.>>>..>>.....<<......>
>>>>>>.<<<<.....>>>>..>>>....<<<<....<<<<<.<<<.<<.
........<.....<<<<<.....<..>......>>>>><<.<<<<<<<<
<<<....>>>>>..>>>>>>.>>............<<<<<<<<<..<<<.
........>>>..<<<<<<<....<<<<.....>>>>......>>>>>>>
...<<..<<<..<<<<<<....<<<.....<<<<....>>>>.....>>>
.>>>>..>>>>>.<<<<<.......>>>>>.........<..........
.<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>..
>>.>>>>>>>>.>>>>>>....>>....<<<<<........>>>>>....
<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<...<<
<<.<<<...>>>.>>>>...<<<<<.....<<<..............<<<
<<<<..>>>>>>>...>>>..>>>>>......>>>>>>>..>>>>>...<
<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<.
..<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>...
<<<..<<<<.......>>>>..>>>.<<<....>>>.>>)))].....<<
<<<<<..<<<..)))))).>>>>>>>>>>.........>>>>..>>>>>>
.......<<.<...<<<<<<...<<.......>>...>>>>>>....>.>
.>.......<<<<<.<<<<<<..<.<.<<<<<......>>>>>...>.>.
<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<<<..
..>>>.>>>>....>>..>>>.>>>>>.......<<<<<<<<..<<<..<
.<<<<<.................>>>>>.><<<<....<<<<....<<<<
<<<<<.]]]..>>>>..>>>>>...>>>>...>>>><<<<<...<<<<<.
..........>>>>>...>>>>>.>>>...>>>>>>>>.<<<<<<...<.
..<<<<....<<..........<<<<<..>>>>>.........>>...<<
<.<..<<...<<<..........>>>.........>>...>.>>>.....
.........>>>>....>>>>>>>.<<<...<.............>....
<<<<<<<<<<..<.....<<<<....<<<<..>>>>...>>>>....>..
...>>>>.>>>>>>...>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oya A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
A2 K3 R4 T5 K6 K7 V8 G9 G12 K13 Y14 G15 T16 R17 Y18 G19 A20 S21 L22 R23 H34 F41 C42 K44 K46 R49 A51 V52 G58 S59 K62 W69
Binding residue
(residue number reindexed from 1)
A1 K2 R3 T4 K5 K6 V7 G8 G11 K12 Y13 G14 T15 R16 Y17 G18 A19 S20 L21 R22 H33 F40 C41 K43 K45 R48 A50 V51 G57 S58 K61 W68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oya, PDBe:7oya, PDBj:7oya
PDBsum7oya
PubMed36653451
UniProtA7YY10

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