Structure of PDB 7r72 Chain p Binding Site BS01

Receptor Information
>7r72 Chain p (length=337) Species: 1247190 (Saccharomyces cerevisiae BY4741) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSG
HSGPIRAVKYISNTRLVSAGNDRTLRLWKTKNNIEDGKTLAILEGHKAPV
VSIDVSDNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAA
RKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHT
IKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRQQ
QLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITREDK
SVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKADN
Ligand information
>7r72 Chain 1 (length=641) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
augccugaauagggugaagccagaggaaacucugguggaggcucgcgaau
uuggguauaguagcaaauauucaaaugagaacuuugaagacugaaguggg
gaaagguuccacgucaacagcaguuggacguggguuagucgauccuaaga
gaugguuucaaaggccugauucaggccaccaucgaaagggaauccgguua
agauuccggaaccuggauauggauucuucacgguaacguaacugaaugug
gagacgucggcgcgagcccugggaggaguuaucuuuucuucuuaacagcu
uaucaccccggaauugguuuauccggagauggggucuuauggcuggaaga
ggccagcaccuuugcuggcuccggugcgcuugugacggcccgugaaaauc
cacaggaaggaauaguuuucaugccaggucguacugucuccaaggugaac
agccucuaguugauagaauccguaacuucgggauaaggauuggcucuaag
ggucggguagugagggccuuggucacggccuuggcuugcuacaauuaacg
aucaacuuagaacugguacggacaauaucuagcgaggcugucugaucagg
cauugcguaagcaguagaguagccguuacgaucugcugaga
<<<<<<<<...<<<....<<<<<<<....>>>>>>>.....>>>......
>>>>>>>>....<<.....<<<<<<.......>>>>>><<<<.....<<<
<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<
............<<<<<<...>>>>>>....>>....>>...<<<<<...
.....>>>>>))<<<<.<<<<<<......<<<....>>>.......<<<<
<<...<<<<.<<<<<<<.<<<<<<<<<<..(((..>>>>>><...<<<<<
....<<<<<<....<<<.....>>>....>>>>>>.....>>>>>....>
<<<<<<<......>>>>>>>>>>>...>>>>>>>.>>>>.........>>
>>>>............>>.>>>>>>>>>>>>..>>.>>>>>.<<<<....
.>>>>..>>>>..<<<<.<<<<<<.<<<<.....................
<<<<<.<<<<<<<<..<<..<<<<..>>>>..>>>>>>>>>>......>>
>>>......>>>...>>>>>>>.....>>>>>>...<<<<<<<))).>>>
>>..>>....<<<<....<<.......>>...>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7r72 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4.
Resolution3.07 Å
Binding residue
(original residue number in PDB)		T156 R157 K171 K173 N174 K199 I237 K239 K256 T259 A260 K263 T273 R275
Binding residue
(residue number reindexed from 1)		T64 R65 K79 K81 N82 K88 I126 K128 K145 T148 A149 K152 T162 R164
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:0051276 chromosome organization
GO:0110136 protein-RNA complex remodeling
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7r72, PDBe:7r72, PDBj:7r72
PDBsum7r72
PubMed36482249
UniProtQ12024|YTM1_YEAST Ribosome biogenesis protein YTM1 (Gene Name=YTM1)

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