Structure of PDB 7asp Chain p Binding Site BS01

Receptor Information
>7asp Chain p (length=154) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLVE
QRSGRDALEVFEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLR
WLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFA
HYRW
Ligand information
>7asp Chain X (length=1447) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacguuagcggcggacgggugaguaacacguggau
aaccuaccuauaagacugggauaacuucgggaaaccguagcuaauaccgg
auaauauagaaagacacuuauagauggauccgcgcugcauuagcuaguug
guaagguaacggcuuaccaaggcaacgaugcauagccgaccugagagggu
gaucggccacacuggaacugagacacgguccagacuccuacgggaggcag
caguagggaaucuuccgcaaugggcgaaagccugacggagcaacgccgcg
ugagugaugaaggucuucggaucguaaaacucuguuauuagggagaacau
augugcacaucuugacguaccuaaucagaaagccacggcuaacuacgugc
cagcagccgcgguaauacguagguggcaagcguuauccggaauuauuggg
cguaaagcgcgcguaggcgguuuuuuaagucugaugugaaagcccacggc
ucaaccguggagggucauuggaaacuggaaaacuugagugcagaagagga
aaguggaauuccauguguagcggugaaaugcgcagagauauggaggaaca
ccaguggcgaaggcgacuuucuggucuguaacugacgcugaugugcgaaa
gcguggggaucaaacaggauuagauacccugguaguccacgccguaaacg
augagugcuaaguguuagggggugccccuuagugcugcagcuaacgcauu
aagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaauu
gacggggacccgcacaagcgguggagcaugugguuuaauucgaagcaacg
cgaagaaccuuaccaaaucuugacauccuuugacaacucuagagauagag
ccuaaagugacagguggugcaugguugucgucagcucgugucgugagaug
uuggguuaagucccgcaacgagcgcaacccuuaagcuuaguugccaucau
uaaguugggcacucuaaguugacugccggugacaaaccggaggaaggugg
ggaugacgucaaaucaucaugccccuuaugauuugggcuacacacgugcu
acaauggacaauacaaagggcagcgaaaccgcgaggucaagcaaucccau
aaaguuguucucaguucggauuguagucugcaacucgacuacaugaagcu
ggaaucgcuaguaaucguagaucagcaugcuacggugaauacguucccgg
gucuuguacacaccgcccgucacaccacgagaguuuguaacacccgaagc
cgguggaguaaccuuuuaggagcuagccgucgaaggugggacaaaugauu
ggggugaagucguaacaagguagccguaucggaaggugcggcuggau
......<<<....[....>>>..<<...<<<.<...<<..........<<
<.......<................>.......<<........<..<<..
..<<....<<<..................<....>...............
...................>>>...>>.>.>..>..<<....<<......
.....................>>......>>...<<<<.<<<....>>>.
...>>>>.>>.<<<<<.<.........>>>>>>..<<.....>>......
..>>>.........<<<....<<<<....>>>>..>>>........>>..
...<<.......<<......>>......>>....................
...............................<<<<<.((....<<<<...
.....))..........>>>>.>>>>>..>.>>>..>>............
.<<..................<<<......<...................
....................>........>>>..................
...........<<.......<........>..........>>........
..................................................
..............<<<<.........>>>>...................
......((...............................((..>>))...
..))..........<........<<<....>>>......>.....]....
.....<<<.........<<<<<....<<<<<<..................
...............<<<.......<<.<<......<<<<......>>>>
....>>..>>...........<<.<<<........<.<<...........
.................>>>........<<<...................
...........................<<<.....>>>...........>
>>.......>.>>....>>...........>>>.........>>>>>>..
.................<<...........................>>..
.........................<<..........>>...........
...>>>>>..........................................
.>>>............<.......<..<<....<<<<<..<<<<....<.
<<<<<..................>.>>>>.>...>>>>..>>>>>....>
>.>........>...........<<<<..........>>>>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7asp Staphylococcus aureus 50S after 30 minutes incubation a 37C
Resolution2.86 Å
Binding residue
(original residue number in PDB)		R3 G5 S6 V7 L32 D33 K76 A77 R78 R95 Y107 A108 R109 L110 R111 G112 E113 T115 M116 N122 W156
Binding residue
(residue number reindexed from 1)		R2 G4 S5 V6 L31 D32 K74 A75 R76 R93 Y105 A106 R107 L108 R109 G110 E111 T113 M114 N120 W154
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7asp, PDBe:7asp, PDBj:7asp
PDBsum7asp
PubMed
UniProtA0A077VHU6

[Back to BioLiP]