Structure of PDB 8ip9 Chain oa Binding Site BS01

Receptor Information
>8ip9 Chain oa (length=136) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGEEFQHILRVLNTNVDGKQKIMFALTSIKGVGRRFSNIVCKKADIDMNK
RAGELSAEEMDRLMAVVHNPRQFKVPDWFLNRKKDYKDGRFSQVVSNAVD
MKLRDDLERLKKIRNHRGLRHYWGVRVRGQHTKTTG
Ligand information
>8ip9 Chain aa (length=1695) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaauccgaugauucaugauaacucgacggaucgcacg
gccuucgugccggcgacgcaucauucaaauuucugcccuaucaacuuucg
augguaggauaggggccuaccaugguggugacgggugacggagaauuagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccaauccugacacggggagguagugacaau
aaauaacaauaccgggcgcauuagugucugguaauuggaaugaguacaau
cuaaaucccuuaacgaggauccauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuuaaguuguugcaguuaaaa
agcucguaguuggaccuugggccggccggcaucgcgcuccuagcccggca
ucguuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggau
acauuagcaugggauaacaucauaggauuccgguccuauuguguuggccu
ucgggaucggaguaaugauuaauagggacagucgggggcauucguauuuc
auagucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaa
gcauuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucg
aagacgaucagauaccguccuagucucaaccauaaacgaugccgaccagg
gaucggcggauguugcuuauaggacuccgccggcaccuuaugagaaauca
aagucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggcguggagccugcgcuuaauuugacuc
aacacggggaaacuuaccagguccagacauagcaaggauugacagacuga
gagcucuuucuugauucuaugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccguuaacgaacgagaccucagccugc
uaacuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacu
auggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcc
cuuagauguucugggccgcacgcgcgcuacacugauguauucaacgagua
uauagccuuggccgacaggcccggguaaucuugggaaauuucaucgugau
ggggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaag
cgcgagucaucagcucgcguugacuacgucccugcccuuuguacacaccg
cccgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggc
gacggacgucgcgagaaguccauugaaccuuaucauuuagaggaagcaga
agucguaacaagguuuccguaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>..........<<<..<<....>>..>>>.
<...<<<<<<..................>>>>>>.....>...<<<<.<<
<<......>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>....>.
>.....<<<...<.................>...>>>......<<..<..
.........>..>>.........<<<<<((....<.<<<<.....<<..)
)>>.......>>>>>>>>>>..>>>>>>>>>..........<.<((....
.<.<<...<<<.<.....<.<<<<..>>>>.>..................
..<<<<<<.<<.......<<...<.......>...<.......>.....>
>......>>.>>..>>>>........<...<<<<<<<.............
..>>>>>>>...>......>....<<<<<<.<<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<.<<<.<.....>>>>>>>>>>>>..>>>...<<..))>>.
..>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<....
....>>..........<<<<<.<....<<<<<........<<.<<<....
....>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<
<<<..<<...<<<<<<<......>>>>>>>.....>>..>>>>.>>....
.<<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<..
.....<<<.<<<<....>>>>.>>>....>>........>.>>>>.....
.<....<<<<<<..........>>>>>>....>.....>>>>>>....<<
<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<
..<<.<.<<.<<.<<....<<<<<<<..<<<..<<<<..<...<<<..<<
.......>>..>>>...>..>>>>..>>>..>>>>>>>...>>.>>.>>.
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ip9 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K25 F28 K34 G35 V36 G37 R38 R39 F40 R55 W82 F83 N85 K87 K88 H120 R121 R124 H125 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139
Binding residue
(residue number reindexed from 1)		K21 F24 K30 G31 V32 G33 R34 R35 F36 R51 W78 F79 N81 K83 K84 H116 R117 R120 H121 R126 V127 R128 G129 Q130 H131 T132 K133 T134 T135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ip9, PDBe:8ip9, PDBj:8ip9
PDBsum8ip9
PubMed38267667
UniProtQ8L806

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