Structure of PDB 8qu5 Chain o Binding Site BS01

Receptor Information
>8qu5 Chain o (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQERGHAAVRRREAFEA
IKAAATSKFPPHRFIADQLDHLNVTKKWS
Ligand information
>8qu5 Chain A (length=1049) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccaaaccuuagccaa
accauuuacauaaaguauaggcgauagaaauugggcgcaauagauauagu
accgcaagggaaagaugaaaaauaccaagcauaauauagcaaggacuaac
cccuauaccuucugaugaauuaacuagaaauaacuuugcaaggagagcca
aagcuaagacccccgaaaccagacgagcgccuggugauagcugguugucc
aagauagaaucuuaguucaacuuuaaauuugcccacagaaccaaaucccc
uuguaaauuuaacuguuaguccaaagaggaacagcucuuuggacacuagg
aaaaaaccuuguagagagaguaaaaaauuuaacacccauaguaggccuaa
aagcagccaccaauuaagaaagcguucaagcucaacaccucccaaacaua
uaacugaacuccucacacccaauuggaccaaucuaucacccuauagaaga
acuaauguuaguauaaguaacaugaaaacauucuccuccgcauaagccug
cgucagaucacugacaauuaacagcccaauaucuacaaucaaccaacaag
ucauuauuacccucacugucaacccaacaggcaugcucauaaggaaaggu
uaaaaaaaguaaaaggaaacaucaccucuagcaucaccaguauuagaggc
cagcugucucuuacuuuuaaccagugaaauugaccugcccgugaggcggg
cauaacacagcaagacgagacccuauggagcuuuaauuuauuaaugcaaa
caccugcauuaaaaauuucgguuggggcgaccucggagcagaacccaacc
uccgagcaguacaugcuaagacuucaccagucaaagcgaaccucaauuga
uccaauaacuugaccaacggaacaaguuacccuaggguaucuacuuuauu
ccucccuguacgaaaggacaagagaaauaaggccuacuucacaaagcgcc
uucuaaaugauaucaucucaacuuaauacccacacccaagaacaggguu
<<<.......<<<<..................................<.
.....>...........<<.....>>.......>>.>>............
.<<....>>..................>>>...........<<<......
.>>>...<.<....>.>.<<<<<<.........<<<.<<..<<....>>.
..>>.>>>...<<.<...<<<<.<....>.>>>>......>.>>..<<<<
<<....<<<<....>>>>.<<.<<<<<<<<<<.....<<......>>...
..>>>>>>>>>>..>>..<<<<<<<<<<......>>>>>>>>>>...<<<
......>>>....<<<.<<<...<..............<....<<<....
.....>>>....>.......<<<......>>>..................
....>...>>>>>>........>>>>>>...<<<<<......>>>>>...
......>>>>>><......<<..<<<....>>><<<<..<<<<.......
.<<<<<....>>>>>......<<<...<<<<...................
....>>>>.......>>>.....<<....>>.>>>>.....>>>>..<<<
<...<<<<<<<<.<<.........<<<<<<.............>>>>>>.
.......>>.>>>>>>>>>>>>.>>.....>.....<<<<<.....>>>>
>.......<<..<<<.....<<<<<.<<<<<<..<<<<<.<<<<<<<<..
....>>>>>>>>>>>>>..<<<<.....>>>><<<<<<...........>
>>>>>..<<.....<<<..<<<<.....>>>>..>>>....>>.......
..<<<....>>>............>>>>..>>>>>>>..>>>.>>..<<<
.<<<.................>>>.>>><<<<<...<<<....>>>.>>>
>>.<<<.<............>.>>>........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8qu5 GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Resolution2.42 Å
Binding residue
(original residue number in PDB)		F26 S28 R30 N34 R56 R60 G61 H62 A63 A64 R66 R67 F71 I74 K75 A78 T79 K81 R86 H94
Binding residue
(residue number reindexed from 1)		F3 S5 R7 N11 R33 R37 G38 H39 A40 A41 R43 R44 F48 I51 K52 A55 T56 K58 R63 H71
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8qu5, PDBe:8qu5, PDBj:8qu5
PDBsum8qu5
PubMed38969660
UniProtQ9BQC6|RT63_HUMAN Large ribosomal subunit protein mL63 (Gene Name=MRPL57)

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