Structure of PDB 8p2h Chain o Binding Site BS01

Receptor Information
>8p2h Chain o (length=60) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKG
QIPGVRKASW
Ligand information
>8p2h Chain a (length=1534) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuagggggccccuu
agugcugcagcuaacgcauuaagcacuccgccuggggaguacgaccgcaa
gguugaaacucaaaggaauugacggggacccgcacaagcgguggagcaug
ugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugacauccuu
ugacaacucuagagauagagccuuccggacaaagugacagguggugcaug
guugucgucagcucgugucgugagauguuggguuaagucccgcaacgagc
gcaacccuuaagcuuaguugccaucauuaaguugggcacucuaaguugac
ugccggugacaaaccggaggaagguggggaugacgucaaaucaucaugcc
ccuuaugauuugggcuacacacgugcuacaauggacaauacaaagggcag
cgaaaccgcgaggucaagcaaaucccauaaaguuguucucaguucggauu
guagucugcaacucgacuacaugaagcuggaaucgcuaguaaucguagau
cagcaugcuacggugaauacguucccgggucuuguacacaccgcccguca
caccacgagaguuuguaacacccgaagccgguggaguaaccuuuuaggag
cuagccgucgaaggugggacaaaugauuggggugaagucguaacaaggua
gccguaucggaaggugcggcuggaucaccuccuu
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<
<.<<<..<<<..<<.<<<<...<<<..........>>>...>>>>.>>>>
>......<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<
<<<<....>>>>>>......>>>>......<<<<<<<<<<..>>>>>>>>
>>......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....
<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<
....>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>...>>>>>>>........<<<....<<<<....>>>>..>>>..>>
.>>>>>>..<<<<......<<<<....>>>>.....>>>>...<<<<<<<
.......<.<<<<<<<........>>>>>>>.>........>>>>>>...
>..<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<
<<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......
>>>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>..>>>>>....<<<<<<<...<...<<<<.........>
>>>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<..>>>>>
>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<<....
>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<
<<<<......<<........>>..........<<<<<<<......<<<<<
<......<<<<....>>>>...........>>>>.>>.<<<.<<<..<<<
<<<.......<<<<<<<<<....>>>..<<<<......>>>>..>>>>>>
.....<<<<.<<<<<<<..<<..<<<......>>>>>...>>>>>>>...
..<<<<<.....>>>>>........>>>>.........>>>...>>>>>>
>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<
<...<<<....>>>...>>....>>>.....>>>>>>>......<....<
<<<<<<........>>>>>>>....>.....>>>>>>....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<<..<<<...>>>.>
>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>.>>...>.....<
<<<<<<<<....>>>>>>>>>.............
Receptor-Ligand Complex Structure
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PDB8p2h Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid with a tRNA in pe/E chimeric hybrid state
Resolution2.49 Å
Binding residue
(original residue number in PDB)		A2 K3 T4 S5 M6 A8 K9 K12 K15 Y16 A17 V18 R19 Y21 T22 R23 C27 R29 H31 S32 V33 R35 R41 I42 R45 K58 S60 W61
Binding residue
(residue number reindexed from 1)		A1 K2 T3 S4 M5 A7 K8 K11 K14 Y15 A16 V17 R18 Y20 T21 R22 C26 R28 H30 S31 V32 R34 R40 I41 R44 K57 S59 W60
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8p2h, PDBe:8p2h, PDBj:8p2h
PDBsum8p2h
PubMed38902339
UniProtQ2FW19|RS14Z_STAA8 Small ribosomal subunit protein uS14B (Gene Name=rpsZ)

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