Structure of PDB 8buu Chain o Binding Site BS01

Receptor Information
>8buu Chain o (length=87) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ITQERKNQLINEFKTHESDTGSPEVQIAILTDSINNLNEHLRTHKKDHHS
RRGLLKMVGKRRNLLTYLRNKDVTRYRELINKLGLRR
Ligand information
>8buu Chain A (length=2852) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgauga
aggacgggacgaacaccgauaugcuucggggagcuguaagcaagcuuuga
uccggagauuuccgaauggggaaacccaccacucguaauggagugguauc
cauaucugaauucauaggauaugagaaggcagacccggggaacugaaaca
ucuaaguacccggaggaagagaaagcaaaugcgauucccugaguagcggc
gagcgaaacgggauuagcccaaaccaagaggcuugccucuugggguugua
ggacacucuguacggaguuacaaaggaacgagguagaugaagaggucugg
aaaggcccgccauaggagguaacagcccuguagucaaaacuucguucucu
ccugaguggauccugaguacggcggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaagag
auccugaaaccgugugccuacaaguagucagagcccguuaacgggugaug
gcgugccuuuuguagaaugaaccggcgaguuacgaucccgugcaagguua
agcagaagaugcggagccgcagcgaaagcgagucugaauagggcgcauga
guacguggucguagacccgaaaccaggugaucuacccauguccaggguga
aguucagguaacacugaauggaggcccgaacccacgcacguugaaaagug
cggggaugagguguggguaggggugaaaugccaaucgaaccuggagauag
cugguucucuccgaaauagcuuuagggcuagccucaagguaagagucuug
gagguagagcacugauuggacuaggggccgguuaccgaauucagucaaac
uccgaaugccaaugacuuauccuugggagucagacugcgagugauaagau
ccguagucgaaagggaaacagcccagaccgccagcuaaggucccaaagua
uacguuaaguggaaaaggauguggaguugcuuagacaacuggucgaguga
cucugcgccgaaaauguaccggggcuaaacguaucaccgaagcugcggac
uguucgaacagugguaggagagcguucuaagggcugugaagccagaccgg
aaggacugguggagcgcuuagaagugagaaugccgguaugaguagcgaaa
gaggggugagaauccccuccaccgaaugccuaagguuuccugaggaaggc
ucguccgcucaggguuagucgggaccuaagccgaggccgaaaggcguagg
cgauggacaacagguugauauuccuguaccaccuccucaccauuugagca
auggggggacgcaggaggauaggguaagcgcgguauuggauauccgcguc
caagcaguuaggcugggaaauaggcaaauccguuucccauaaggcugagc
ugugauggcgagcgagcgaaguuccugauuccacacugccaagaaaagcc
ucuagcgaggugagaggugcccguaccgcaaaccgacacagguaggcgag
gagagaauccuaaggugaucgagagaacucucguuaaggaacucggcaaa
augaccccguaacuucgggagaaggggugcucuguuagggugcaagcccg
agagagccgcagugaauaggcccaggcgacuguuuagcaaaaacacaggu
cucugcgaagccguaaggcgaaguauaggggcugacgccugcccggugcu
ggaagguuaagaggagcgcuuagcguaagcgaaggugcgaauugaagccc
caguaaacggcggccguaacuauaacgguccuaagguagcgaaauuccuu
gucggguaaguuccgacccgcacgaaaggcgcaacgaucugggcacuguc
ucaacgagagacucggugaaauuauaguaccugugaagaugcagguuacc
cgcgacaggacggaaagaccccguggagcuuuacugcagccugauauuga
auguugguacagcuuguacaggauagguaggagccuuggaaaccggagcg
ccagcuucgguggaggcaucggugggauacuacccuggcuguauugaccu
ucuaacccgccgcccuuaucgggcggggagacagugucaggugggcaguu
ugacuggggcggucgccuccuaaaagguaacggaggcgcccaaagguucc
cucagaaugguuggaaaucauucgcagaguguaaaggcacaagggagcuu
gacugcgagaccuacaagucgagcagggacgaaagucgggcuuagugauc
cggugguuccgcauggaagggccaucgcucaacggauaaaagcuaccccg
gggauaacaggcuuaucucccccaagaguccacaucgacggggagguuug
gcaccucgaugucggcucaucgcauccuggggcuguagucagucccaagg
guugggcuguucgcccauuaaagcgguacgcgagcuggguucagaacguc
gugagacaguucggucccuauccgucgcgggcgcaggaaauuugagagga
gcuguccuuaguacgagaggaccgggauggacgcaccgcugguguaccag
uuguucugccaagggcaucgcuggguagcuaugugcggacgggauaagug
cugaaagcaucuaagcaugaagccccccucaagaugagauuucccauucc
gcaaggaaguaagaucccugaaagaugaucagguugauaggucugaggug
gaaguguggcgacacauggagcugacagauacuaaucgaucgaggacuua
ac
<<<<<<......<<<<<<<<<<<.....[[..[[<<<<<<<[[<<.....
.<<<<<<..[..((.>>>.....<<<<<<<..<<<))..]..>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>.>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>...<<<<......<<...
..>>.....>>>>...(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<.....<<<<.......<<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>>>>
>>.>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
........>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<.<<<<<..<<<..
.<<<.....>>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>.>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>...>..
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<<...<<<<<<<<
<.....<<<...<<<<<<<<...<<.<<..>>..>>...>>>>>>>>..>
>.>.....>>>>.>>>>>..>>>>>>>.>>..<<<<<<<.<<......>>
.>>>>>>>....<<<......>>>...<<<<.<<<...<<<(((.....<
<<<<<...........<<..<<<<<<<<<........<<..>>....>>>
>>>>>>.>>...........))).....>>>>>>.>>>...>>>>>>><<
<<<<..>>>>>>....>>>>>>..<<<<<<<.<<......<<<<<.<<..
..>>.>>>>>...>>.>>>>>>>........>>>>>><......<<....
<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<<<...<<.
....>>.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>
>...>>...<<<<<........>>>>>))<<<<<.<<<<<<......<<.
..<<<<....<<<<..<<<..<<<.<<<<<<<<...(((....>>>>>><
<..<<<<<..<<<<<<<<<<<.<<.....>>>>>>>>>....>>>>..>>
>>>...>><..<<..>>...>>>>>>...>>>...>>>>.........>>
>>..>>..>>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>>..<<<<....<<<<<<<<.<<............
...<<<<<.....<..>......>>>>><<<<<....<<<<....>>>>.
..>>>>>............<<<<<<<<<..<<<.........>>>..<<<
<<<<.....<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<
<<..<<<...<<...<<<<<..<<....>>...>>>>>...>>...>>>>
>>>>..>>>>><<<<<<.......>>>>>>........<...........
<<<<<<.....>>>>>>.....>....>>>>...>>.>>>>>>>.....>
>.>>>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<
<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<
<.<<<<<<<<<<<<...........<<<<<..<<<......<<<<<<<<.
...>>>>>>>>...>>>............>>>>>..>>>>>>>>>>>>.>
>>....<<.<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>.
.<<<<.....>>>><<<<<<...........>>>>>>..<<...<<<<<<
<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>>.
..<<<<..<<<......>>>..>>>>.<<<....>>>.>>)))]......
<<<<<<<.((..>>>>..))>>>>>>>.............>>>>..]]>>
>>.......<<<<...<<<<<<...<<.......>>...>>>>>>....>
>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>>>..>
>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....<<<<<<<
....>>>.>>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<.
.<<<<<<<...............>>>>>>>.<<<<<...<<<<...<<<<
<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>...<<<....<<<
<<...........>>>>>....>>>.>>>>.......>>>>>>>..<<<<
....>>>>....<<<<<<<<<.......>>>>>....<<<<<<<<.<<<.
...<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>>>>
>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8buu Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
V60 R63 R88
Binding residue
(residue number reindexed from 1)
V58 R61 R86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8buu, PDBe:8buu, PDBj:8buu
PDBsum8buu
PubMed36951104
UniProtP21473|RS15_BACSU Small ribosomal subunit protein uS15 (Gene Name=rpsO)

[Back to BioLiP]