Structure of PDB 8a3w Chain o Binding Site BS01

Receptor Information
>8a3w Chain o (length=88) Species: 347515 (Leishmania major strain Friedlin) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRTVKMGVMGRYGTRYGANPRKRAKKLEVSQHAKHFCSFCGKFAFRRKA
VGIWRCDGCSKTVAGGAYTLSTPNNSTVRSTVRRLREL
Ligand information
>8a3w Chain 2 (length=947) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccaacugcagaccguacucaucaccgcaucagguccccaagcauagaaug
cucugguacauagagaaagguacacucagggaagucggcaaaauagaugc
guaaguucgcaagaagcauuggcucugagggcaaaauugccaacucagaa
cugcuuacggcggggaauccaacuguauaauuaaaacauagguuugugau
gcauccaagugguguauaucgcaaacugauuucugcccagugcucuguca
acgugacgagauucaccgacgcgcggguaaacggcgggcucucuuaaggu
agccaaaugccucgucuuccaauuagagacgcgcaugaauggauuaauga
gauucccucugucccgaguuacuaucuagcgaaacgacagucaagggaac
ggacuugaagggcuaagcggggaaagaagacccuguugaguuugacucca
gucuggcucugugcgguucacuuaucgaaugaagagaccaauggguuuag
cguagucuggcuaugcaccgucuagguuccgugcuguaaacugaaccaac
gggaguuccggagucuuguuucgagacaucugccagauggggaguuuggc
uggggcggcauaucuguuacacgacaacgcagguguccuaaggcgagcuc
agugggaucucacguagaacacaagcguaaaagcuugcuugauuaacgau
uuccaguacgaaucgagacugcgaaagcaaggccagcgauccuuugcgau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaaggcuu
gauccuucgaugucggcucuuccuaaccuagcggcuaaggguuggauugu
ucacccacugacagggaacgugagcuggguuuagaccgucgugagacagg
uugguuuuacccuacuuagcuggaaauugcgagaaaaauccguaagc
.......................<<......>>......<<<<<...>>>
>>........<<<<....<<<<.<<<<.<<.........<.....<<<<<
....<<..>>.....>>>>><<.<<<<<<<<<<<..>>>>>..>>>>>>.
>>..........<<<<<<<<<..<<<.........>>>..<<<<<<<...
.<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<.<<..
..<<<<......>>>>....>>..>>>>..>>>>><<....>>.......
.<...........<<<<<.......>>>>>.....>.....>>....>>.
>>>>>>>..>..>>.>>>>>>>>.>>>>............<<<<<.....
...>>>>>..<<<<<<<..<<<.<<......<<<<.<<<<<<..<<<<<.
<<<<<<<...<<<.<.>.>>>...<<<<<.....<<<<...........<
.<<<.........>>>.>...............................<
<<<...>>>>..>>>>...>>>>>.......>>>>>>>..>>>>>...<<
<.....>>>..<<<<<<...........>>>>>>..<<...<<<<<<<..
.<<<<<..>>>>>.....<<......>>....>>>>>>>...<<...<<<
<<.......>>>>>..>>.<<<....>>>.>>.........<<<<<..<<
<.......>>>..>>>>>..........>>>>..>>>>>>.....<<.<.
>.>.>.......<<<<<.<<<<<<..<<<<<<.>>>..>>>.<<<.....
....>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>
>>....>>..>>>.>>>>>>>..........................
Receptor-Ligand Complex Structure
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PDB8a3w CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : WILD TYPE
Resolution2.89 Å
Binding residue
(original residue number in PDB)
V6 K7 M8 T16 R17 G19 A20 N21 R23 F41 K62
Binding residue
(residue number reindexed from 1)
V5 K6 M7 T15 R16 G18 A19 N20 R22 F40 K61
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8a3w, PDBe:8a3w, PDBj:8a3w
PDBsum8a3w
PubMed
UniProtQ4QC01

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