Structure of PDB 7p48 Chain o Binding Site BS01

Receptor Information
>7p48 Chain o (length=87) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLRTHKKDHH
SRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIR
Ligand information
>7p48 Chain A (length=2661) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgauga
aggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuuga
uccagagauuuccgaauggggaaacccagcaugaguuaugucauguuauc
gauaugugaauacauagcauaucagaaggcacacccggagaacugaaaca
ucuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggc
gagcgaaaugggaagagcccaaaccaacaagcuugcuuguugggguugua
ggacaggaguuacaaaggacgacauuagacgaaucaucuggaaagaugaa
ucaaagaagguaauaauccuguagucgaaaauguugucucucuuccugag
uacgacggagcacgugaaauuccgucggaaucugggaggaccaucuccua
aggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaa
ggugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugc
uuacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaa
ugaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagc
cguagcgaaagcgagucugaauagggcguuuaguauuuggucguagaccc
gaaaccaggugaucuacccuuggucagguugaaguucagguaacacugaa
uggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggu
agcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaaua
gcuuuagggcuagccucaagugaugauuauuggagguagagcacuguuug
gauucagacaaacuccgaaugccaauuaauuuaacuugggagucagaaca
ugggugauaagguccguguucgaaagggaaacagcccagaccaccagcua
aggccccaaaauauauguuaaguggaaaaggauguggcacugcgccgaaa
auguaccggggcuaaacauauuaccgaagcuguggauuguccggacaaug
guaggagagcguucuaagggcguugaagcaugaucguaaggacaugugga
gcgcuuagaagugagaaugccggugugaguagcgaaagacgggugagaau
cccguccaccgauugacuaagguuuccagaggaaggcucguccgcucugg
guuagucggguccuaagcugaggccgacaggcguaggcgauggauaacag
guugauauuccuguaccaccuauaucgauggggggacgcaguaggauagg
cgaagcgugcgauuggauugcacgucuaagcaguaaggcugaguauuagg
caaauccgguacucgggcugagcugugauggggagaucgagucguugauu
ucacacugccgagaaaagccucuagauauaggugcccguaccgcaaaccg
acacagguagucaagaugagaauucuaaggugagcgagcgaacucucguu
aaggaacucggcaaaaugaccccguaacuucgggagaaggggugcucuuu
aggguuaacgcccagaagagccgcagugaauaggcccaagcgacuguuua
ucaaaaacacaggucucugcuaaaccguaaggugauguauaggggcugac
gccugcccggugcuggaagguuaagaggagugguuagcgcgaagcuacga
aucgaagccccaguaaacggcggccguaacuauaacgguccuaagguagc
gaaauuccuugucggguaaguuccgacccgcacgaaaggcguaacgauuu
gggcacugucucaacgagagacucggugaaaucauaguaccugugaagau
gcagguuacccgcgacaggacggaaagaccccguggagcuuuacuguagc
cugauauugaaauucguggcuuucuaacccgcaccacuuaucgugguggg
agacagugucaggcgggcaguuugacuggggcggucgccuccuaaaaggu
aacggaggcgcucaaagguucccucagaaugguuggaaaucauucauaga
guguaaaggcauaagggagcuugacugcgagaccuacaagucgagcaggg
ucgaaagacggacuuagugauccggugguuccgcauggaagggccaucgc
ucaacggauaaaagcuaccccggggauaacaggcuuaucucccccaagag
uucacaucgacggggagguuuggcaccucgaugucggcucaucgcauccu
ggggcuguagucggucccaaggguugggcuguucgcccauuaaagcggua
cgcgagcuggguucagaacgucgugagacaguucggucccuauccgucgu
gggcguaggaaauuugagaggagcuguccuuaaccgggauggacauaccu
cugguguaccaguugucgugccaacggcauagcuggguagcuaugugugg
acgggauaagugcugaaagcaucuaagcaugaagccccccucaagaugag
auuucccaacuucgguuauaagaucccucaaagaugaugagguuaauagg
uucgagguggaagcauggugacauguggagcugacgaauacuaaucgauc
gaagacuuaau
<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<.....
.<<<<<<.[...((.>>>.....<<<<<<<..<<<))...].>>>.....
>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<
<<<<<<<.........>>>>>>>.>>.>>.....<<<<......<<....
>>.......>>>>...........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<..<<<<.......<<<<<<<<<<.<<<...<<<<<......>>>>>(
(......<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>>>...
..<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>.
.)))......]].>>>>>>>.]]...............<<....>>....
]].........<<<<....>>>>.............}....>>>>>>>>>
>>.......<<<<..<<<<......>>>>..>>>>...<.<........>
.>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>
>...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.
<...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>
>.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>
...<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<
<<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<
<..>>>>>>>..>>.>.....>>>>>.>>>>..>>>>>>>.>>..<<<<<
<<<<<......>>>>>>>>>>....<<<......>>>...<<<<.<<<..
.<<.(((.....<<<<<<...........<<..<<<<..>>>>.>>....
.......))).....>>>>>>..>>...>>>>>>><<<<<<..>>>>>>.
...>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>>>>>...
>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<.......
>>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>
....((<<<<.<<.<.<<<...<<<....>>>...>>>..>>>...<<<<
<........>>>>>))<<<<<<.<<<...<<<<....<<<<..<<<..<<
<<<.<<<<<<...(((...>>>>>><<..<<<<<..<<<.<<<<<<..<<
.....>>.>>>>>>..>>>..>>>>>...>>...<..>...>>>>>...>
>>...>>>>.........>>>>..>>>.>>>>>>>>>>..>>.....<<.
.....>>>>>>>.<<<.......>>>..>>>>..<<<<....<<<<<<<<
.<<...............<<<<<...............>>>>><<<<<<<
.<<<<....>>>>.>>>>>>>............<<<<<<<<<..<<<...
......>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<
<<<.<<<..<<<<<<<..<<<<..<<...<<<<<<.<..>..>>>>>>..
.>>..>>>>>>>>>..>>>>><<<<<<.......>>>>>>........<.
..........<<<<<<.....>>>>>>.....>....>>>>>..>>.>>>
>>>>.....>>.>>>>>>>>.>>>>>>.....>.....<<<<<.......
.>>>>>..<<<<<<<<.(((.[[......<<<<.[[<<<<..<<<<<.<<
<<<<<<<.<<<<.<<..>>.>>>>....<<.<<<<<<.....>>>>>>>>
.....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<........
...>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....
<<.[.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<
<<....>>>.>>)))]......<<<<<<<.((..>>>>..))>>>>>>>.
............>>>>..]]>>>>.......<<<<...<<<<<<...<<.
......>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<
<<<<<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>.
.>...>>>.>>....<<<<<<<....>>>.>>>>....]]..)))>>>>>
>>>....<<<<<<<...<<<<..<<<<<<<.....>>>>>>>.<<<<<..
.<<<<...<<<<<<<<<<<.)))>>>>>>..>>>>>...>>>>.>>>>>.
..<<<.<..<<<<<...........>>>>>...>>>>.>>>>.......>
>>>>>>.<<<....>>>....<<<<<<<<<.......>>>>>....<<<<
<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>
....>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7p48 Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		N40 L57 V60 R88
Binding residue
(residue number reindexed from 1)		N39 L56 V59 R87
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7p48, PDBe:7p48, PDBj:7p48
PDBsum7p48
PubMed35137182
UniProtW8U6H8

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