Structure of PDB 7oyd Chain o Binding Site BS01

Receptor Information
>7oyd Chain o (length=102) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQ
TKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKG
QV
Ligand information
>7oyd Chain 5 (length=3358) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacccggcgccggggggcccaaguccuucugau
cgaggccgcccguggacggugugaggccgguagcggcccccggcgcgccg
ggcccgggucuucccggagucggguugcuugggaaugcagcccaaagcgg
gugguaaacuccaucuaaggcuaaauaccggcacgagaccgauagucaac
aaguaccguaagggaaaguugaaaagaacuuugaagagagaguucaagag
ggcgugaaaccguuaagagguaaacgggugggguccgcgcaguccgcccg
gaggaucaacccggcggcggccggccgugccggggggcggaucuggaccg
ccccccggccggcgaccggccgccgccgggcgcauuuccaccgggcggug
cgccgcgaccggcuccgggacggcugggaaggcccggcggggaagguggc
ccggccggguguuacagcccgcccccggcagcagcgacucgccgaauccc
ggggccgagggagcgagacccgugccgccgcgcucuccccccuggggggg
ccgggccaccccucccacggcgcgaccgcggggcggacuguccagugcgc
cccgggcgggucgcgccgucgggcccggggggccacgcgcgagcgcacgg
ggucggcggcgaugucggcuacccacccgacccgucuugaaacacggacc
aaggagucuaacacgugcgcgagucgggggcuacgaaagccgccguggcg
caaugaaggugaaggccgggccgaggugggaucccgaggccucuccaguc
cgccgagggcgcaccaccggcccgucucgcccgccgcgccggggaggugg
agcacgagcgcacguguuaggacccgaaagauggugaacuaugccugggc
agggcgaagccagaggaaacucugguggagguccguagcgguccugacgu
gcgaaucggucguccgaccuggguauaggggcgaaagacuaaucgaacca
ucuaguagcugguucccuccaaaguuucccucaggauagcuggcgcucuc
gcaguuuuauccgguaaagcgaaugauuagagguaccuauucucaaacuu
uaaauggguaagaagcccggcucgcugguguggagccgggcguggaaugc
gagugccuagugggccacuuuugguaagcagaacuggcgcugcgggauga
accgaacgccggguuaaggcgcccgaugccgacgcucaucagaccccaga
aaagguguugguugauauagacagcaggaugguggccauggaagucggaa
uccgcuaaggaguguguaacaacucaccugccgaaucaacuagcccugaa
aauggauggcgcuggagcgucgggcccauacccggccgucgcuggcaguc
ggcagagcgagaaagagagugggcggacgcuacgccgcgacgaguaggag
ggccgcugcggugagccuugaagccuagggcgcgggcccggguggagccg
ccgcaggugcagaucuuggugguaguagcaaauauucaaacgagaacuuu
gaaggccgaaguggagaaggguuccaugugaacagcaguugaacaugggu
cagucgguccugagagaugggcgagcgccguuccgaagggacgcucagcc
gaucgaaagggagucggguucagauccccgaauccggagcggagaugggc
guccagugcgguaacgcgaccgaucccggagaagccggcgggagccccgg
ggagaguucucuuuucuuugugaagggcagggcgcccuggaauggguucg
ccccgagagaggggcccgugccuuggaaagcgucgcggcguccggugagc
ucucgcuggcccuugaaaauccgggggagaggguguaaaucucgcgccgg
gccguacccauauccgcagcaggucuccaaggugaacagccucuggcaug
uuggaacaauguagguaagggaagucggcaagccggauccguaacuucgg
gauaaggauuggcucuaagggccgacuuagaacuggugcggaccagggga
auccgacuguuuaauuaaaacaaagcaucgcgaaggcccgcggcgggugu
ugacgcgaugugauuucugcccagugcucugagucaaagugaagaaauuc
aaugaagcgcggguaaacggcgggaguaaugacucucuuaagguagccaa
augccucgucaucuaauuagugacgcgcaugaauggaugaacgagauucc
cacugucccuaccuacuauccagcgaaaccacagccaagggaacgggcuu
ggcggaaucagcggggaaagaagacccuguugagcuugacucuagucugg
cacggugaauucacugacccggugaggcgggggggccucgcuucuggcgc
caagcgcccgcgggcgcgacccgcuccggggacagugccagguggggagu
uugacuggggcgguacaccugucaaacgguaacgcagguguccuaaggcg
agcucagggaggacagaaaccucccguggagcagaagggcaaaagcucgc
uugaucuugauuuucaguacgaauacagaccgugaaagcggggccucacg
auccuucugaccuuuuggguuuuaagcaggaggugucagaaaaguuacca
cagggauaacuggcuuguggcggccaagcguucauagcgacgucgcuuuu
ugauccuucgaugucggcucuuccuaucauugugaagcagaauucaccaa
gcguuggauuguucacccacuaauagggaacgugagcuggguuuagaccg
ucgugagacagguuaguuuuacccuacugaugauguguuguugccauggu
aauccugcucaguacgagaggaaccgcagguucagacauuugguguaugu
gcuuggcugaggagccaauggggcgaagcuaccaucugugggauuaugac
ugaacgccucuaagucagaaucccgcccaggcggaacgauagcgccggag
ccucgguuggccucggauagccggccggugcggagagcccuucgucccgg
gaaacgggccggaaaggggccgcgcccgucacgcaccgcacguucguggg
gaaccuggcgcuaaaccauucguagacgaccugcuucugggucgggguuu
cguacguagcagagcagcugcgaucuauugaaagucagcccucgacacaa
ggguuugu
.........................<<<<<<.....<......>......
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..>>>>>..<<<<<<<<<.<<<<<<..<.<<<<<<<<....<<<<.....
.>>>>...((......<<<.....))>>>...>.>>>>>>>...>.>>>>
>>...>>>>>>>>>.......<<<<<<<........>>>>>>>.....((
(((..<<<<<<)))))..]]].............................
.....<<....>>...............<<<<....>>>>..........
........................<<<<<<<<..<<<.<<...<<<<<<<
<.<<<....<<<<<<<<<<<<<<<<<<.<<<<<<<<<<<<.<<..>>>>>
>>>>>>>>>>>>>...>>>>>>>>>>>>>>......>>>.>>>>>>>>..
.<<<<<<<<<<<<<<<<<<.<<<<...<<..<<<.<<..<<<......<<
<<<..>>>>>.......>>>..>>..>>>.........>>>>>>...>>>
>>>>>>>.....<<.......>>......<<<<<<.<<<<<<..>>>>>>
...<.<<..<<<.<<<<<<<<<<<<<<.<<<<<<<.<<<<..>>>>.>>>
>>>..>..>>>>>>>>>>>.>>>...>>>>>.>.......>>>>>>....
.>>>.>>>>>...>>>>>...>>>>>>>>..<<<<........>>>><<<
<<<....<<<<<<<<<<<<<..<<<...<<<<.....>>>>.....>>>.
..<<....>>...<<<<.>>>>..<<<<<...<<<..<<.....(((.[[
..>>..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>>>
.>>....>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<<.
.<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<...
.....>>>>.>>>....>>>>>>>>>...<<.......>>......>>>>
>>...>..>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<..
<<<.<<<<<<<<<...<<<....<<<..<.<<<..>>>.>..>>>..>.>
>...>>>>>>>...<<<<<<<<<.<......>>>>>>>>>>....>>>>>
>>>>>>>..>>..<<<<.<<<<<.....>>>>>.>>>>....<<<.....
.>>>...<<<<<<<...<<<(((.......<<<<<......<........
..<<<.<<<<<<<<<<.......<<<<<.<<....<<.........>>..
..>>.........<<......>>...>>>>>...>>>>>>>>>>>>>...
.......))).>....>>>>>..>>>...>>>>>>><<<<<<.<<<....
................]].)))...........>>>>>>>>>....>>>>
>>...<<<<<<<<.<<......<<<<.<<<<....>>>>>>>>...>>>>
>>>>>>........>>>>>><<.....<<.....<<<<<<.......>>>
>>>.<<<.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>..
..((<<<<<<...<<....<<<....>>>..........<<...>>....
..>>....>>>..<<<<<........>>>>>))<<<<.<<<<<..<<<<.
.>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<<<.<<<<
<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<.....<<<....
.>>>.....>>>>>>>>..>>>>>.....<<<<<..>>>>>>>>>...>>
>>>>>>>>>>.........>>>>>>>..>..........>>.>>>.>>>>
.>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>...
.<<<<.....<<<<<<<.<<.........<.....<<<<<..........
.....>>>>><<.<<<<<<......>>>>>>.>>............<<<<
<<<<<..<<<.........>>>..<<<<<<<....<<<<.....>>>>..
....>>>>>>>...<<..<<<..<<<<<<...<<.....<<<<....>>>
>.....>>..>>>>..>>>>><<<<<<....>>>>>>........<....
.......<<<<<.......>>>>>.....>.....>>....>>.>>>>>>
>..>..>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>
>>....[[[[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<<<<
<<<.<<<<..>>>>...<<<<<.....<<<<..<<..>>...........
...<<<<<<..>>>>>>..>>>>..>>>>>....>>>>>>>>>..>>>>>
...<<<.....>>>..<<<<<<...........>>>>>>..<<...<<<<
<<<...<<<<<<.......>>>>>>.....<<.[.(((>>....>>>>>>
>...<<<..<<<<.......>>>>..>>>.<<<....>>>.>>)))]...
...((((((..(((..>>>>>>.)))))))))..........]]]]..}}
]]]].......<<.<.<.<<<<<<...<<.......>>...>>>>>>...
>>.>.>.......<<<<<.<<<<<<..<.<.<<<<<......>>>>>...
>.>.<<<.........>>>.....>>>>>..>...>>>.>>....<<<<<
<<....>>>.>>>>....}}..}}}.]]]]].....<<<<<<.<..<<<.
.<.<<<<<.................>>>>>.><<<<....<<<<....<<
.<<<<<<.}}}..>>>>..>>.>>...>>>>...>>>><<<<....<<<<
<...........>>>>>....>>>>.>>>...>.>>>>>>.<<<<<<<..
<<<<....<<<........<<<<..>>>>.......>>>...<<<..<<<
<......<<<.......>>>....>>>>..>>>..............>>>
>..>.>>>>>>.<<<<<.<.............>....<<.<<<<<<<.<<
.....<<<<....<<<..>>>...>>>>....>>....>>>>.>>>.>>.
.>>>>>..
Receptor-Ligand Complex Structure
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PDB7oyd A molecular network of conserved factors keeps ribosomes dormant in the egg.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
V2 N3 P5 R8 R9 T10 F11 K14 K17 H18 Y26 K28 G29 K30 D31 S32 Y34 A35 Q36 G37 R39 R40 R43 K44 G47 Y48 G50 Q51 K53 P54 I55 F56 R57 K58 A60 K61 T63 K64 K65 K80 R81 M82 K86 C88 K89 K97 K98 K100
Binding residue
(residue number reindexed from 1)
V1 N2 P4 R7 R8 T9 F10 K13 K16 H17 Y25 K27 G28 K29 D30 S31 Y33 A34 Q35 G36 R38 R39 R42 K43 G46 Y47 G49 Q50 K52 P53 I54 F55 R56 K57 A59 K60 T62 K63 K64 K79 R80 M81 K85 C87 K88 K96 K97 K99
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oyd, PDBe:7oyd, PDBj:7oyd
PDBsum7oyd
PubMed36653451
UniProtG1T040|RL36A_RABIT Large ribosomal subunit protein eL42 (Gene Name=RPL36A)

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