Structure of PDB 6zm5 Chain o Binding Site BS01

Receptor Information
>6zm5 Chain o (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGRIPGRQWIGKHRRPRFVSLRAKQNMIRRLEIEAENHYWLSMPYMTREQ
ERGHAAVRRREAFEAIKAAATSKFPPHRFIADQLDHLNVTKKWS
Ligand information
>6zm5 Chain A (length=1534) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacaccca
cuaccuaaaaaaucccaaacauauaacugaacuccucacacccaauugga
ccaaucuaucacccuauagaagaacuaauguuaguauaaguaacaugaaa
acauucuccuccgcauaagccugcgucagauuaaaacacugaacugacaa
uuaacagcccaauaucuacaaucaaccaacaagucauuauuacccucacu
gucaacccaacacaggcaugcucauaaggaaagguuaaaaaaaguaaaag
gaacucggcaaaucuuaccccgccuguuuaccaaaaacaucaccucuagc
aucaccaguauuagaggcaccgccugcccagugacacauguuuaacggcc
gcgguacccuaaccgugcaaagguagcauaaucacuuguuccuuaaauag
ggaccuguaugaauggcuccacgaggguucagcugucucuuacuuuuaac
cagugaaauugaccugcccgugaagaggcgggcauaacacagcaagacga
gaagacccuauggagcuuuaauuuauuaaugcaaacaguaccaaaccugc
auuaaaaauuucgguuggggcgaccucggagcagaacccaaccuccgagc
aguacaugcuaagacuucaccagucaaagcgaacuacuauacucaauuga
uccaauaacuugaccaacggaacaaguuacccuagggauaacagcgcaau
ccuauucuagaguccauaucaacaauaggguuuacgaccucgauguugga
ucaggacaucccgauggugcagccgcuauuaaagguucguuuguucaacg
auuaaaguccuacgugaucugaguucagaccggaguaauccaggucgguu
ucuaucuacuuucaaauuccucccuguacgaaaggacaagagaaauaagg
ccuacuucacaaagcgccuucccccguaaaugauaucaucucaacuuagu
auuauacccacacccacccaagaacaggguuugu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<..<<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>...>..>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>.<.<<<......>>>.>..<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
...........................>...>>>>>>........>>>>>
>...<<<<<......>>>>>.........>>>>>><......<<..<<<.
...>>><<<...<<<<........<<<<<.<<........>>.>>>>>..
....<<<...<<<<.......................>>>>.......>>
>.....<<......>>.>>>>......>>>..<<<<...<<<<<<<<.<<
.........<......<<<<<<..<<<.........>>>...<<<<<<..
...........>>>>>>....<<<.<<<..<<<<<....>>>..>>>>><
<<<<<......>>>>>>........<...........<<<<<<.....>>
>>>>.....>....>>>....>>.>>>>.....>..>>.>>>>>>>>>>>
>.>>.....>.....<<<<<........>>>>>.......<<..<<<.<<
......<<<<.<<<<<<..<<<<<.<<<<<<<<....<..>......>>>
>>>>>>>>>>..<<<<.....>>>><<<<<<...........>>>>>>..
<<.....<<<..<<<<.....>>>>..>>>...........>>.......
..<<<....>>>............>>>>..>>>>>>.......<<<..<.
<<<<<<...<<.......>>...>>>>>>...>.>>.>.......<<<<<
.<<<<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>
>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....
>>..>>>.>>...<.<<<.<<<.................>>>.>>><<<<
<...<<<....>>>.>>>>>......<<<................>>>..
....>..........<<<<.......>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6zm5 Mechanism of membrane-tethered mitochondrial protein synthesis.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		R9 R11 I12 P13 G14 R15 Q16 W17 I18 G19 K20 H21 R22 R23 R25 F26 S28 R30 N34 R56 E59 R60 G61 H62 A63 R66 R67 F71 I74 K75 A78 T79 K81 R86 H94
Binding residue
(residue number reindexed from 1)		R1 R3 I4 P5 G6 R7 Q8 W9 I10 G11 K12 H13 R14 R15 R17 F18 S20 R22 N26 R48 E51 R52 G53 H54 A55 R58 R59 F63 I66 K67 A70 T71 K73 R78 H86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6zm5, PDBe:6zm5, PDBj:6zm5
PDBsum6zm5
PubMed33602856
UniProtQ9BQC6|RT63_HUMAN Large ribosomal subunit protein mL63 (Gene Name=MRPL57)

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