Structure of PDB 6yly Chain o Binding Site BS01

Receptor Information

>6yly Chain o (length=125) Species: 4932 (Saccharomyces cerevisiae)

EYSGIIYVSRLPHGFHEKELSKYFAQFGDLKEVRLARNKKTGNSRHYGFL
EFVNKEDAMIAQESMNNYLLMGHLLQVRVLPKGAKIEKLYKYKKRVPVKQ
LKDNMKQKHEERIKKLAKSGIEFKW

Ligand information

>6yly Chain 6 (length=65)

ccuucucaaacauucuguuugguagugagugauacucuuuggaguuaacu
ugaaauugccuuaaa

......<<<<<<...>>>>>>.....<<<<...<<<<....>>>>..>>>
>..............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6yly Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
• Resolution: 3.8 Å
• Binding residue (original residue number in PDB): Y94 R97 H100 R124 N125 K126 N130 R132 H133 Y134 F136 L157 H160 E174 K175 L176 Y177 Y179 K181 K203 R207
• Binding residue (residue number reindexed from 1): Y7 R10 H13 R37 N38 K39 N43 R45 H46 Y47 F49 L70 H73 E87 K88 L89 Y90 Y92 K94 K108 R112

Gene Ontology

Molecular Function

• GO:0003674 molecular_function
• GO:0003676 nucleic acid binding
• GO:0003723 RNA binding
• GO:0005515 protein binding
• GO:0019843 rRNA binding

Biological Process

• GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0006364 rRNA processing
• GO:0042254 ribosome biogenesis
• GO:0042273 ribosomal large subunit biogenesis

Cellular Component

• GO:0005634 nucleus
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0030687 preribosome, large subunit precursor
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6yly, PDBe:6yly, PDBj:6yly
• PDBsum: 6yly
• PubMed: 32668200
• UniProt: P53927|NOP15_YEAST Ribosome biogenesis protein 15 (Gene Name=NOP15)