Structure of PDB 5opt Chain o Binding Site BS01

Receptor Information
>5opt Chain o (length=140) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRRIGKKKGATMKDVHPWRWVKLCSQHFKQEGKLMVPNCTEIVKSSHGRE
RAPQNPDWYYIRCAAILRAVYMRPGVGYGGLSKRFSNKKNRGSRPEITVR
ASKGLLHWGCKSLTKLGLIEKCESSGHRITKNGRKLADAI
Ligand information
>5opt Chain E (length=2022) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcauugcaggaaucugcgcauggcucauua
caucagacguaaucugccgcaaaaaucuugcggucuccgcaacauuggau
aacuuggcgaaacgccaagcuaauacaugaaccaaccggauguucucugu
uccggcggcagggcaaccugcugccaugggacguccagcgaaugaaugaa
aguaaaaccaaugccuucaccggcaguaacacucagaaguguugauucaa
uucauuccgugcgaaagccggguuuuuuuauccggcgucuuuugacgaac
aacugcccuaucagccagcgauggccguguaguggacugccauggcguug
acgggagcgggggauuaggguucgauuccggagagggagccugagaaaua
gcuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugucaaa
aaaaaaagaugaggcagcgaaaagaaauagagccgacagugcuuuugcau
ugucguuuucaaugggggauauuuaaacccauccaaaaucgaguaacaau
uggaggacaagucuggugccagcacccgcgguaauuccagcuccaaaagc
guauauuaaugcuguugcuguuaaaggguucguaguugaauugagggccu
cuaaggcgcaaugguuuagucccauccacuucggauuggugacccaugcc
cuugugguccgugaacgacauucagaaacaaaaaacacgggagugguacc
uuuccugauuaucgcaugucaugcaugccagagggcgcccgugauuuuuu
acugugacuaaaaaagugugaccaaagcagucauucgacuugaauuagaa
agcaugggauaacaaaggagcagccucugggccaccguuucggcuuuugu
ugguuuuaaaaguccauuggagauuauggggcagugugacaagcggcugu
cgccuuugugggaaaugccuucccucaacucacggcauccaggaaugaag
gaggguaguucgggggagaacguacuggugcgucagaggugaaauucuua
gaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuucc
ucaaucaagaaccaaaguguggggaucgaagaugauuagagaccauugua
guccacacugcaaacgaugacacccaugaauuggggacucagcacguuau
cugacuucuucacgcgaaagcuuugagguuacagucucaggggggaguac
guucgcaagagugaaacuuaaagaaauugacggaauggcaccacaagacg
uggagcgugcgguuuaauuugacucaacacggggaacuuuaccagauccg
gacagggugaggauugacagauugaguguucuuucucgauccccugaaug
guggugcauggccgcuuuuggucgguggagugauuuguuugguugauucc
gucaacggacgagauccaagcugcccaguaggauucagaauugcccaucc
cuuccgcggguuuuacccaagggggggcgguauucgcuuguauccuucuc
ugcgggauuccuuguuuugcgcaaggugagauuuugggcaacagcagguc
ugugaugcuccucaauguucugggcgacacgcgcacuacaaugucaguga
gaacaagaaaaacgacucuugucggaccuacuugaucaaaagagugggaa
aaccccggaaucacguagacccacuugggaccgaguauugcaauuauugg
ucgcgcaacgaggaaugucucguaggcgcagcucaucaaacugugccgau
uacgucccugccauuuguacacaccgcccgucguuguuuccgaugauggu
gcaauacaggugaucggacagucgagugcuucacuugaccgaaaguucac
cgauauuucuucaauagaggaagcaaaagucguaacaagguagcuguagg
ugaaccugcagcuggaucauuu
...<<<<....{{{{.>>>>{{{{.[[[[[[...[[[..........[[[
.[[[..<<....<<....<<<<...>>>>...>>.>>......{{.....
...[[[..[[..[[...[[.[[.....<<<<<<...>>>>>>...<<...
..<<<<<<.....>>>>>>......>>..........<<<<<.<<<....
...<<<<<<<<<....>>>>>>>>>...>>>>>>>>.[[((((((((...
...<<<<<<<<<<<<......>>>.........................)
)))))))...]]....<<<<<<........>>>>>>...]].]]..]]]]
..]]].<<<....<<<....<<<<<.<<.......>>.>>>>>>>>....
..>>>..<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<<<<....>>>>...]]]]]].........<<<....<<<...
.......>>>..>>>.......]]]....<<<.<<<<<<<<<....>>>>
>>>>>..>>>.....<<<<............>>>.....>.........<
<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>..]]
]]]]}}}}.........{{{{{.....[[[[...[[[..{....<<<<<.
<.<<<<.<<<.<<<.............................>>>>>>>
>>>>.>>>>>.........................<<<<<<.......<<
<<<............<<.......>>....>>>>>..>>>>>>.....<<
<<<<<<.......<<...<.......>..<<<....>>>.....>>....
..>>>>>..>>>...........[[..(((((..<<.....>>.....>>
>>>>>>>....)))))..]].......<<<.<.<<<.<.....<<<...>
>>........<<<......>>>......>.>>>.>..>>>.....}....
..<<<<<..<<...<<<<<<<<..<<<<<<<<...<<<......>>>...
...>>>>>>>.>.>>.......<<....>>.>>>>>>..>>.>>>.>>..
..]]]...]]]]...<<<<<<<<...<...<<<<.........>>>>...
>>>>>>>>>.........<<<.<<...<..<<<<<..............>
>>>>..>......<<..}}>>.....>>.....>>>.}}}.<<<......
<<<<....>>>>....>>>..}}}}..<<<<<.<<<<<<<..<<.<<<<<
<.....<<<<<........<<........>>..........<<.<<....
..<<<<<........<<.<<<........>>>.>>......>>>>>...<
<.<<<.....<<<<<<....<<<.<<<<<....>>>...<<<......>>
>...>>.>>>....<<<<<.<<<<.....<<<<<....<.........<.
<<<<<..<<<.....>>>..>>>>>.>......>.......>>>>>....
.>>>>...<..<.<<.....>>>..>.......>>>>>....>>>.>>>.
......>>>>>.......>.>.>>.......>>>>>..............
..........................<<<<<<<........>>>>>>>..
..........................<....<<<................
>>>.....>.....>>>>>>....<<<<<<<.........>>>>>>>...
...>>...>>>>>>>>>>.>>....<..<<.<.<<<<<<<<..<<.<<<.
<.<<<<..<<<<<.<...<.<<<<<<<<...>>>>>>>>.>...>.>>>>
>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>.....<<<<<<<<<
....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5opt The cryo-EM Structure of a Novel 40S Kinetoplastid-Specific Ribosomal Protein.
Resolution4.0 Å
Binding residue
(original residue number in PDB)
I12 R13 A21 T22 Q41 E42 M46 N49 V54 S56 H58 R73 A75 A76 I77 R79 A80 V81 Y82 M83 P85 G86 V87 G88 Y89 S93 K94 F96 S97 N98 K99 N101 R102 G103 S104 R105 P106 E107 V110 R111 S113 K114 I130 E134 H138 R139 K142 N143 K146 L147 D149
Binding residue
(residue number reindexed from 1)
I1 R2 A10 T11 Q30 E31 M35 N38 V43 S45 H47 R62 A64 A65 I66 R68 A69 V70 Y71 M72 P74 G75 V76 G77 Y78 S82 K83 F85 S86 N87 K88 N90 R91 G92 S93 R94 P95 E96 V99 R100 S102 K103 I119 E123 H127 R128 K131 N132 K135 L136 D138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5opt, PDBe:5opt, PDBj:5opt
PDBsum5opt
PubMed29107485
UniProtQ4DJY1

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