Structure of PDB 8ip9 Chain na Binding Site BS01

Receptor Information
>8ip9 Chain na (length=125) Species: 4565 (Triticum aestivum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VFGVAHIFASFNDTFIHVTDLSGRETLVRITGGMKVKADRDESSPYAAML
ASQDVATRCKELGITALHIKLRATGGNKTKTPGPGAQSALRALARSGMKI
GRIEDVTPVPTDSTRRKGGRRGRRL
Ligand information
>8ip9 Chain aa (length=1695) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugugcaaguaugaaccaauuugaacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguacgugcuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucugggaggggc
gcauuuauuagauaaauccgaugauucaugauaacucgacggaucgcacg
gccuucgugccggcgacgcaucauucaaauuucugcccuaucaacuuucg
augguaggauaggggccuaccaugguggugacgggugacggagaauuagg
guucgauuccggagagggagccugagaaacggcuaccacauccaaggaag
gcagcaggcgcgcaaauuacccaauccugacacggggagguagugacaau
aaauaacaauaccgggcgcauuagugucugguaauuggaaugaguacaau
cuaaaucccuuaacgaggauccauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuuaaguuguugcaguuaaaa
agcucguaguuggaccuugggccggccggcaucgcgcuccuagcccggca
ucguuacuuugaagaaauuagagugcucaaagcaagccaucgcucuggau
acauuagcaugggauaacaucauaggauuccgguccuauuguguuggccu
ucgggaucggaguaaugauuaauagggacagucgggggcauucguauuuc
auagucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaa
gcauuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucg
aagacgaucagauaccguccuagucucaaccauaaacgaugccgaccagg
gaucggcggauguugcuuauaggacuccgccggcaccuuaugagaaauca
aagucuuuggguuccggggggaguauggucgcaaggcugaaacuuaaagg
aauugacggaagggcaccaccaggcguggagccugcgcuuaauuugacuc
aacacggggaaacuuaccagguccagacauagcaaggauugacagacuga
gagcucuuucuugauucuaugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccguuaacgaacgagaccucagccugc
uaacuagcuaugcggagccaucccuccgcagcuagcuucuuagagggacu
auggccguuuaggccacggaaguuugaggcaauaacaggucugucaugcc
cuuagauguucugggccgcacgcgcgcuacacugauguauucaacgagua
uauagccuuggccgacaggcccggguaaucuugggaaauuucaucgugau
ggggauagaucauugcaauuguuggucuucaacgaggaaugccuaguaag
cgcgagucaucagcucgcguugacuacgucccugcccuuuguacacaccg
cccgucgcuccuaccgauugaaugguccggugaaguguucggaucgcggc
gacggacgucgcgagaaguccauugaaccuuaucauuuagaggaagcaga
agucguaacaagguuuccguaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>..........<<<..<<....>>..>>>.
<...<<<<<<..................>>>>>>.....>...<<<<.<<
<<......>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....
<<<<<<<<.......>>>>>>>>>>>......>>>...<<<.<<<<....
>>>>....>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>
...>>>>>>.........<<<....<<<.....>>>..>>>..>....>.
>.....<<<...<.................>...>>>......<<..<..
.........>..>>.........<<<<<((....<.<<<<.....<<..)
)>>.......>>>>>>>>>>..>>>>>>>>>..........<.<((....
.<.<<...<<<.<.....<.<<<<..>>>>.>..................
..<<<<<<.<<.......<<...<.......>...<.......>.....>
>......>>.>>..>>>>........<...<<<<<<<.............
..>>>>>>>...>......>....<<<<<<.<<...<<<<..<<..<<<<
<<<<...<<<......>>>......>>>>>>>>..>>.......<<....
>>...>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<.
..<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<
..<<<<<<<<.<<<.<.....>>>>>>>>>>>>..>>>...<<..))>>.
..>>.....>>>.>.>.<<<......<<<<....>>>>....>>>..)))
).]<<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<.......<<....
....>>..........<<<<<.<....<<<<<........<<.<<<....
....>>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<..<
<<<..<<...<<<<<<<......>>>>>>>.....>>..>>>>.>>....
.<<<<<.....>>>>>........>>>>>....>>>.>>>.....>>>>>
>>.....>.>>>>>......>>>>.>>>.....<<<<.<.......<<..
.....<<<.<<<<....>>>>.>>>....>>........>.>>>>.....
.<....<<<<<<..........>>>>>>....>.....>>>>>>....<<
<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>....<
..<<.<.<<.<<.<<....<<<<<<<..<<<..<<<<..<...<<<..<<
.......>>..>>>...>..>>>>..>>>..>>>>>>>...>>.>>.>>.
.>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ip9 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		H32 F34 N38 D39 F41 H43 S48 G49 R50 E51 T52 R55 T57 G59 D65 R66 V135 P136 T137 D138 T140 R141 R142 K143 G144 G145 R146 R147 R149 R150 L151
Binding residue
(residue number reindexed from 1)		H6 F8 N12 D13 F15 H17 S22 G23 R24 E25 T26 R29 T31 G33 D39 R40 V109 P110 T111 D112 T114 R115 R116 K117 G118 G119 R120 R121 R123 R124 L125
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ip9, PDBe:8ip9, PDBj:8ip9
PDBsum8ip9
PubMed38267667
UniProtA0A3B6SS17

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