Structure of PDB 8ev3 Chain n Binding Site BS01

Receptor Information
>8ev3 Chain n (length=362) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKAGAARIYITRNQALKKLQLTLADFRRICILKGVYPREPKNKKKANKVT
FYYTKDIQYLLHEPIVQKFREYKVFARKLSKALGKGELETAKRLEARKPT
YSLDHIIKERYPTFHDALKDIDDALSMLFLFSTMPVTDKIGAATVANCER
LCAEFQHYVIRSNSLRKAFLSIKGIYYQAEIFGEQITWIVPYKFAQSVPT
DVDFRIMHTFLEFYQALMGFVNFKLYNTLGLRYPPKIDVAKSESAAGLAA
YELEESNTSLFSNFTFFLSREVPRFSLEFVIRAFGGKVGWDPILGSGSPF
SESDPVITHHICDRPHISQKYEGRIYIQPQWVYDSINKGILERTDLYACG
ATLPPHLSPFVK
Ligand information
>8ev3 Chain 2 (length=150) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaaacuuucagcaacggaucucuuggcucucgcaucgaugaagaacgcag
cgaaaugcgauacguaaugugaauugcagaagaaucaucgaaucuuugaa
cgcacugcgccuuuggguucuaccaaaggcaugccuguuugagugucauu
..........................................<<<<<<<<
.....>>>>.....<.<<<.......>........>>>..>...>>>...
.<<...>><<<<<<<<......>>>>>>>>....................
Receptor-Ligand Complex Structure
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PDB8ev3 Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A10 G11 R14 I15 Q70
Binding residue
(residue number reindexed from 1)		A3 G4 R7 I8 Q58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
GO:1902626 assembly of large subunit precursor of preribosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030687 preribosome, large subunit precursor
GO:0070545 PeBoW complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ev3, PDBe:8ev3, PDBj:8ev3
PDBsum8ev3
PubMed36423630
UniProtO60164|PESC_SCHPO Pescadillo homolog (Gene Name=ppp1)

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