Structure of PDB 8a98 Chain n Binding Site BS01

Receptor Information

>8a98 Chain n (length=33) Species: 347515 (Leishmania major strain Friedlin)

GTVSRPRGMRPKWHKKRIKRLKLRRRRMRQRSK

Ligand information

>8a98 Chain S1 (length=1727)

gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcaugcaggaaucugcgcauggcucauuac
aucagacguaaucugccgcaaaaaucuugcggccgcaaaauuggauaacu
uggcgaaacgccaagcuaauacaugaaccaaccgggugucuccacugaga
cgcccagcgaaugaaugacaguaaaaccaaugccugcaguaacacccagc
aguguugacucaauucauuccgcgaaagccggcuuccggcgucuuuugac
gaacaacugcccuaucagcuggugauggccguguaguggacugccauggc
guugacgggagcgggggauuaggguucgauuccggagagggagccugaga
aauagcuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugu
caaaacaaaacgaugaggcagcgaaaagaaauagaguuguuucaaugggg
gauauuuaaacccaucccgaguaacaauuggaggacaagucuggugccag
cacccgcgguaauuccagcuccaaaagcguauauuaaugcuguugcuguu
aaaggguucguaguugaacugugggcuggcccuugcagcccgugaaagaa
acaagaaacacgggagugguugcaugucaugcaugccguccgugauuuuu
uacugugacuaaagaagcgugacuaaagcagucaugacuugaauuagaaa
gcaugggauaacaaaggagcuuuuuaaagguauuggagauuauggagcug
ugcgacaaaugcuuucuaggaaugaaggaggguaguucgggggagaacgu
acuggggcgucagaggugaaauucuuagaccgcaccaagacgaacuacag
cgaaggcauucuucaaggauaccuuccucaaucaagaaccaaagugugga
gaucgaagaugauuagagaccauuguaguccacacugcaaacgaugacac
ccaugaauuggggauaucuugcacguuuucuguuuucacgcgaaagcuuu
gagguuacagucucaggggggaguacguucgcaagagugaaacuuaaaga
aauugacggaauggcaccacaagacguggagcgugcgguuuaauuugacu
caacacggggaacuuuaccagauccggacaggaugaggauugacagauug
aguguucuuucucgauucccugaaugguggugcauggccgcuuuuggucg
guggagugauuuguuugguugauuccgucaacggacgagauccaagcugc
ccaguagauuucagaauuuuucgggaauucuucucugcgggauuccuuug
uaugcacaaggugaaauuuugggcaacagcaggucugugaugcuccucaa
uguucugggcgacacgcgcacuacaaugucagugagaacaagaacgaacc
uacuugaucaaaagaguggggaaaccccggaaucacauagacccacuugg
gaccgaggauugcaauuauuggucgcgcaacgaggaaugucucguaggcg
cagcucaucaaacugugccgauuacgucccugccauuuguacacaccgcc
cgucguuguuuccgaugauggugcaauacaggugaucggacaggcgaaag
uucaccgauauuucuucaauagaggaagcaaaagucguaacaagguagcu
guaggugaaccugcagcuggaucauuu

...<<<<<.{.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<.....<......>....>>.>>......<<......
..<<<..<<..<<...<<.<<.....<<<<<..>>>>>...<<.....<<
<<<<.....>>>>>>......>>..........<<<<<<<<<....>>>>
>>>>>.<<<<<<<<<<.....((.((.{..{<<..>>.............
............>>>>>>>>.>>....<<<<<...>>>>>...>>.>>..
>>>>..>>>.<<<....<<<....<<<<<.<<.......>>.>>>>>>>>
......>>>..<<<<<<<<....>>>>...>>>>.>>.<<.<<<......
....>>>.>>.<<<<<..>>>>>...>>>>>>.........<<<....<<
<..........>>>..>>>..>....>>>....<<<....>>>.....<<
<<............>>>>.........<<<<<((....<.<<<<.....<
<..))>>.......>>>>>>>>>>..>>>>>>>>>>.........<<<[[
.....<<<<...<<<.......<...<.......>...>...........
.....<...............<<<<.......>>>>.........>...<
<<<<<<<.......<<...<.......>..<<<..>>>.....>>.....
.>>>>>..>>>..........<<.<<.<<.<...}..}.)).))>..>>.
>>.>>........................<<<<<..<<...<<<<<<<<.
.<<<<.<<<...<<<......>>>......>>>.>>>.>.>>.......<
<....>>.>>>>>>...>>>>>.>>....>>>...>>>>...<<<<<<<<
...<...<<<<.<.....>.>>>>...>>>>>>>>>.........<<<.<
<...<<<<.<<<<<<.<.<.>.>.>>>>>>.>>>>....<<..]]>>...
..>>.....>>>.>>>.<<<......<<<<....>>>>....>>>..)))
).}<<<<<.<<<<<<<..<<.<<<<<<..<<.<<<<<<<......<<...
.....>>..........<<<<<......<<<<.........<<.<<<...
.....>>>.>>.......>>>>.<.<<.<<<..<<.<<<<<<....<<<.
<<<<<....>>>...<<<......>>>...>>.>>>....<<<<<.<<<<
.....<<<.<<<.<<<...>>>..>>>.>>>.....>>>>....<<<<..
.......>>>>.......>>>>>....>>>.>>>.....>>>>>>>>...
...>>>>>...>>.>>>>>.>>.....<<<.<<<.......<......<<
<<<<<........>>>>>>>....>........>>>...>>>......<.
...<<<..<..........>..>>>.....>.....>>>>>>....<<<<
<<<.........>>>>>>>......>>...>>>>>>>>>>.>>....<..
<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.<............>
.>>>>>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>.....<<<<
<<<<<....>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8a98 CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT
• Resolution: 2.46 Å
• Binding residue (original residue number in PDB): G2 T3 V4 S5 R6 G9 M10 R11 P12 K13 W14 K16 K17 R18 K20 L22 K23 R26 R27 S33
• Binding residue (residue number reindexed from 1): G1 T2 V3 S4 R5 G8 M9 R10 P11 K12 W13 K15 K16 R17 K19 L21 K22 R25 R26 S32

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Dec 3 07:34:50 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '8a98', asym_id = 'n', bs = 'BS01', title = 'CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='8a98', asym_id='n', bs='BS01', title='CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '8a98', asym_id = 'n'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='8a98', asym_id='n')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>