Structure of PDB 7nhk Chain n Binding Site BS01 |
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| >7nhk Chain a (length=1517)
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gagaguuugauccuggcucaggacgaacgcuggcggcgugccuaauacau
gcaagucgaacgcuucuuaagaggaguggcggacgggugaguaacacgug
gguaaccuacccaucagagggggauaacacuuggaaacaggugcuaauac
cgcauaacaguuuaugccgcauggcauaagagugaaaggcgcuggugucg
cugauggauggacccgcggugcauuagcuaguuggugagguaacggcuca
ccaaggccacgaugcauagccgaccugagagggugaucggccacacuggg
acugagacacggcccagacuccuacgggaggcagcaguagggaaucuucg
gcaauggacgaaagucugaccgagcaacgccgcgugagugaagaagguuu
ucggaucguaaaacucuguuguuagagaagaacaaggacguuaguaacug
aacguccccugacgguaucuaaccagaaagccacggcuaacuacgugcca
gcagccgcgguaauacguagguggcaagcguuguccggauuuauugggcg
uaaagcgagcgcaggcgguuucuuaagucugaugugaaagcccccggcuc
aaccggggagggucauuggaaacugggagacuugagugcagaagaggaga
guggaauuccauguguagcggugaaaugcguagauauauggaggaacacc
aguggcgaaggcggcucucuggucuguaacugacgcugaggcucgaaagc
guggggagcaaacaggauuagauacccugguaguccacgccguaaacgau
gagugcuaaguguuggaggguuuccgcccuucagugcugcagcaaacgca
uuaagcacuccgccuggggaguacgaccgcaagguugaaacucaaaggaa
uugacgggggcccgcacaagcgguggagcaugugguuuaauucgaagcaa
cgcgaagaaccuuaccaggucuugacauccuuugaccacucuagagauag
agcuuucccgggacaaagugacagguggugcaugguugucgucagcucgu
gucgugagauguuggguuaagucccgcaacgagcgcaacccuuauuguua
guugccaucauuuaguugggcacucuagcgagacugccggugacaaaccg
gaggaagguggggaugacgucaaaucaucaugccccuuaugaccugggcu
acacacgugcuacaaugggaaguacaacgagucgcuagaccgcgagguca
ugcaaaucucuuaaagcuucucucaguucggauugcaggcugcaacucgc
cugcaugaagccggaaucgcuaguaaucgcggaucagcacgccgcgguga
auacguucccgggccuuguacacaccgcccgucacaccacgagaguuugu
aacacccgaagucggugagguaaccuuuuuggagccagccgccuaaggug
ggauagaugauuggggugaagucguaacaagguagccguaucggaaggug
cggcuggaucaccuccu |
..<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.<
<<..<<<..<<.<<<<....>>>>.>>>>>......<<........<<<<
<<<..<<...<<<<<<<.<.<<.....<<<<<......>>>>>......>
>.>.....<.<<<<<<<<<..>>>>>>>>>..>....<<<<<..>>>>>.
>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>>>>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<<<<
.<.........>>>>>>.<<<<....>>>>...>>>>>>.........<<
<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<......<<<<.
...>>>>.....>>>>...<<<<<<<.........<<<<<<<........
>>>>>>>..........>>>>>>...>..<<<<<(((...<<<<<.....
<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<(
(.....<<<<...<<<.<<<<<<<.<<<<<<<<<.......<<<<<<...
..>>>>>>.....>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<
<<....<<<<<<<<<..<<<......>>>.....>>>>>>>>>.......
....<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<
<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........
<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>...<<..))>>.
....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).
]<<<<<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<......
..>>..........<<<<<<<......<<<........<<<<<....>>>
>>....<<<>>>.....>.>>.<<<.<<<..<<<<<<.......<<<<<<
<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<
<..<<<..<<......>>>>>...>>>>>>>.....<<<<<.....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>......<....<<<<<<<........>>
>>>>>....>.....>>>>>>....<<<<<<<.........>>>>>>>..
....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<
..<<<<...<<.<<<<..<<<..<<.....>>.>>>.>>>>.>>..>>>>
..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>
>>>>>............ |
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| PDB | 7nhk Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens. |
| Resolution | 2.9 Å |
Binding residue
(original residue number in PDB) | K13 R14 V17 Y21 Y23 G24 I25 G26 T28 T29 R44 V73 Y86 R87 R90 H91 P96 T97 R98 G99 Q100 N101 T102 K103 N104 N105 A106 R107 T108 R109 K110 K114 T115 |
Binding residue
(residue number reindexed from 1) | K11 R12 V15 Y19 Y21 G22 I23 G24 T26 T27 R42 V71 Y84 R85 R88 H89 P94 T95 R96 G97 Q98 N99 T100 K101 N102 N103 A104 R105 T106 R107 K108 K112 T113 |
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