Structure of PDB 7miz Chain n Binding Site BS01

Receptor Information
>7miz Chain n (length=201) Species: 5811 (Toxoplasma gondii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SQPVFASPLNVEKRRLNEERALMQAQKANIQLPPNYGDMDLILFPEGSLK
NSNNTVIPQSHLKGKSVALYFADGADPKCASLLPFLLNYYRTMNEGGANQ
KIEIIFVSLDRDREAFESHRAHMPWLSIDLENPLTEILKRHFRVMKEYEV
PTYGYGSRTGVPSVIVIGSDGREAQFLPICSGLEEGDRALLRWDWRNTKF
A
Ligand information
>7miz Chain 22 (length=20) Species: 5811 (Toxoplasma gondii) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LPFNAQSCYRSEYVAKPLPP
Receptor-Ligand Complex Structure
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PDB7miz Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		Y154 G162
Binding residue
(residue number reindexed from 1)		Y148 G156
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
Biological Process
GO:0030178 negative regulation of Wnt signaling pathway
GO:0031397 negative regulation of protein ubiquitination
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7miz, PDBe:7miz, PDBj:7miz
PDBsum7miz
PubMed34031406
UniProtQ8MPF4

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