Structure of PDB 7fje Chain n Binding Site BS01

Receptor Information
>7fje Chain n (length=287) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GVTQTPKFQVLKTGQSMTLQCAQDMNHEYMSWYRQDPGMGLRLIHYSVGA
GITDQGEVPNGYNVSRSTTEDFPLRLLSAAPSQTSVYFCASRRRQGASGE
QYFGPGTRLTVTEDLKNVFPPEVAVFEPSEAEISHTQKATLVCLATGFYP
DHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQ
NPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSESY
QQGVLSATIAYEIALGKATLYAVLVSALVLMAMVKRK
Ligand information
>7fje Chain b (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LLDPKLCYLLDGILFIYGVILTALFLRVK
Receptor-Ligand Complex Structure
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PDB7fje Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		F266 Y271 Y282
Binding residue
(residue number reindexed from 1)		F245 Y250 Y261
Enzymatic activity
Enzyme Commision number ?
External links