Structure of PDB 6ywv Chain n Binding Site BS01

Receptor Information

>6ywv Chain n (length=186) Species: 367110 (Neurospora crassa OR74A)

PPLPDIPEGSPKLMEPLVKFVSDELGMDDLKLLDLREIDPPPALGPEVLM
LFGTARSERHLHVSADRLVRWLRNRGVTAKADGLLGRNELKTKLRRKARK
AKLLGTTGLPSGADDGITTGWICVNLGTLGWSDMEMEFKGFGVPQSGTTL
VVQLMTETRREELALEKLWSGILRRSLERQDKIAGK

Ligand information

>6ywv Chain A (length=2529)

guaauggauauaaagcuuauguuuauauauauauauaaguauauaaagag
acuacuaccaauagcuacacuauguauuaaggagaguauaacuuaauuua
uguuuaugauagagguuaucaacauaugaacucuuagagaaauuacuuaa
uaaacgaagugaauugaaauaucuuauuaacuucaggaaaagaaaucaaa
cgagauucuaugauuagugugaacgaaaauagagcagccuauuaaaauaa
guaaaauggcuuuaaagcuguuugaauauuguggggaaccuuccucaaag
gcuaaauauaauacaugaguuacagagaaaaguaccgugagggaaagcuu
ugaaauaguaguuuuauaagcagcucaagcaauaagaaagcgagagcgua
ccuuuugcauaaugggucaccaaguuaauuuuagaugcgagcgaauuaga
ugugcauaguuaaaccgaucauuaaaauaaugaauagugucuaaaguuag
acccgaagccuggugaucuuacuauagucaggacuauaaagguccgaacg
gguuaucguugcaaagauauccgaagaacuaugguaagcgagugaaagac
aacacugacuaggauagcugguuuucugcgaaaccuauaauaguaggcaa
uuuaaguaacaucuuaguagguacagaacuuaaucucagacaagauguag
auuuucauaccuagguaugaaaugcauuuuuuuuuguauacaucgggguu
aucggugaguauguagacucggaaugacaaagaugaaucuugaauaauca
gacauagaaugauaagguuguaugucaaaagggaaacagcccagaacaag
aguuaagguuccaaaauuauuauuaagugaaauaaagaaaguuuuuauau
aagucgacaagaagaugggcuuggaagcagccauaauuuaaagaucucgu
aacagagcacuuguuaaaucuuaaaagcaucgaaaauuuaacggaucuaa
auaauauaccgaaaccuuguccauauguaacauuaguaauaauauuaaug
uuauuugaugggguagcagaacguugagugaaucuuagauuuuuuuuuua
uaacuaaauauagaugauaacucaagugagaauggugacaugaguaacaa
aaaagaguuuaagguaccuaaaagguaucuuagagucucgccuaaagcuu
auggcuacgucaaguaacggccucuaaguuuauaaucugaagauuaugac
gaugagaaaacuuugguaccaacauuuaaaagugaaaauugugcaggaag
gauaaaccguaccuagaaucugaaacaaguaagcuaguagagaauacgaa
ggcgugaaugagauaacaaucauaaaggaacucggcaaacuauaccguaa
cuuagggauaaggagagcauggaauauuguuguacgacuguuuaauuaaa
acaaagcacuuugcaaaaagacgauaagucuaaguauugagugugauuuc
auguaacgauacaacagcugucucuaugauugacucagugaaauuggaau
aacugugcagauacaguuuaccucuaguuagacgagaagacccuaugcag
cuuuacuguuacuaauuauugaauacgaaucguauuauuaaaccuuaaau
uaaggaacaauuguuagaagacaguuuaggccccauaaagaguaaauggg
ugugucuaaaauguuugcaauuuuuuauaguauauaucaaaucaucuuua
ugcuauucauggguacaguauaaaaauuuaagaaauuagguaagauuuug
uuuauagagaaauuagauguaaaaaaaaaaucuuaugagggcggauccgc
uucuaauauuuuuuuguaguuauuauuauaauaauaaucauguuuauuac
uuaaaaagcuuaauggcuuaaucuugccuuacuguuugauuaacaacaaa
ucuuacagucgcguaagcggggcauaggaucacaagauacaaaaaggaaa
gaucuuggauuuuuggaaaagcuacgcuagggauaacaggcuaauuugcg
caagaguguacaaaaugagugcgcgguuuggcaccucgaugucggcuuga
cuaauccucauggaugcagaaacuauguaggguacgacuguucgucgauu
aaaaaguuacaugagcuggguuaaauacgucgugagacaguaugguuucu
aucuucuagagggaauuagaauauaauaaggauuaaccuuuguacgaaag
gaacaugggguacuauuguuauauaacaguuuuauuaaccucugguuuac
cuguuguuuaugugccuuagggauguuaccgucacuugaguaaauacaau
agcauaagcauggcaggaaagcuaaguuagucaaaaauaagugcugaaag
cauauaggcacgaaauuuaccuuaagauauuucuuaaauauacguaagaa
aauauuacguuaauaggcuuaguuuguaaggaacuaaguacuaauuuuau
aaaaaacugaaugauuaauauaucuuaca

<<<<..<<<<<<.......<<<<<<<<<..>>>>...<<<.......<<<
<<<<<<<......<<.....<<<<<<<<<.<<<<<<.....>>.....<<
<<<<................>>>>>>....>>>>..<<....>>......
....<<<<<<.....<......>......>>>>>.>.........<<...
.>>..<<<<<<.....<<....>>....>>>>>>..<<............
...<<<<<<<<....>>>>>>>>........<<<<<..[[[[>>>>>...
>>......>>>>>>>>>.................<<....>>....>>..
.....>>>>>>>>>>.......<<<<..<<.........>>..>>>>...
<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<.......
..>>>...<......>..<<<<<.....>>>>>...>>>>>>>>>>>>>.
.<<.<..<<<<<<<....<<<<<<<<<<..<<<<<....>>.>>>...<<
<..<<<<........>>>>.>>>....>>>>>>>>>>....<<.....>>
.......>>>>>>.>..>.>>..<<<<<<....<<<<<....>>>>>..<
<<<<<<...<<<<<<.<<.....<<<......<<<<<<.<<<<<<<.<.<
..<<<<<<<<<..>>>>>>>>>>>.>>>.....>>>>.....<<<<<..>
.>>>>>>>>.>>.....>>.>.....>>.>>>>>>...>>>>>>>.....
<<<<<<.<<<......>>>.>>>>>>....<<<......>>>...<<<<<
.<<...<<<(((.....<<<<<<.....<<......<<..<<<<<<<...
.....<<<<<<.<....<<<<.......>>>>....>........<<<..
....>>>..>>>>>>......>>>>>>>.>>...........)))>>...
>>>>>>.>>>...>>>>>>><<<<..<<<<<<<<<<<<....>>>>>>>>
>>>>...>>>>....>>>>>>..<<<<<<..<<<....<<..<<..<<..
.>>..>>..>>....>>>.>>>>>>........>>>>>><......<<..
...<<<.<<<<<<<<<<<.....>>>>>>>>>>>.>>><<<<<...<<<<
<.<<........((...<<<.<<<...<<<.<<<<<<<..>>>>>>>>>>
...>>>....)).........<<<.<<..(((((..>>.>>>........
......>>>..>>......<<......>>>>>>>..<<<.....>>>..>
>>>>....<<<<....<<<<<<<<.<<.................<<....
<<..>>.....>>..............<<<<<<<<<..<<<.........
>>>..<<<<<<.......<<<<.....>>>>.......>>>>>>....<.
>.....>>.>>>>>>>.....>>.>>>>>>>>.>>>>>>.....>.....
<<<<<........>>>>>..<<<<<<<..<<<.<<...<<<<<<<.<<<<
<<..<<<<<..<<<<<.<<..<<<<<<<.>>>>>>>......<<<<....
.>>>>....>>.>>>>>...>>>>>....<<<<<<...........>>>>
.>>..<<.....<.......<<<..<<<<...>>>>..>>>.>.......
...<<<<<..>>>>>.......................<<<<<<<.....
<<<<.........>>>>.<<<<..<<<<<<<.<<<.<<.<<<<<..>>>>
>>>>>>.>>>.>>>>...<<<<<<<<<..>>>>>>>>>........>>>>
......<<<...(((>>>...>>>>>>>...<<<<..<<<.........>
>>..>>>>.<<<....>>>.>>))).......<<<<<<.<...]]]]...
>>>>>>>............>>>>..>>>>>>>......<<<<.....<<<
<<...<.........>...>>>>>.....>>>.>.>>......<<<..<<
<<...<<<<<<<<.........>>>>>..>>>..<<<<.....>>>>...
....>>>>......>>>.......<<<<<<<....>>>.>>>>....>>.
.>>>.>>>>>>>.....<<<<<<...<<<<<...<<<<............
......>>......<<<<<<<<>>>>>>>>>>.<<<<<<...<<<<...<
<<<<<<<<<<<<<.<<<..>>>...<<<<...)))))..>>>>.......
.>>>>>>>>>..>>>>>...>>>>.>>>>>>..<<<.<..<<<<<.....
......>>>>>...>>>>.>>>>>...>>>.>>>....<<<.<<<<<...
....>>>>>....<<<<<<<<<<<<....>>.>>>>>>>.>>>.....>>
>....>>>>>>>>.....>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6ywv Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.
• Resolution: 3.03 Å
• Binding residue (original residue number in PDB): R175 D182 R186 R189 R191 G192 G202 R203 N204 E205 K207 R212 R215 W247 Q268
• Binding residue (residue number reindexed from 1): R59 D66 R70 R73 R75 G76 G86 R87 N88 E89 K91 R96 R99 W131 Q145

Gene Ontology

Biological Process

• GO:0048255 mRNA stabilization
• GO:0140053 mitochondrial gene expression

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane

External links

• PDB: RCSB:6ywv, PDBe:6ywv, PDBj:6ywv
• PDBsum: 6ywv
• PubMed: 33056988
• UniProt: Q7SAC2|ATP25_NEUCR ATPase synthesis protein 25, mitochondrial (Gene Name=atp25)