Structure of PDB 6spf Chain n Binding Site BS01

Receptor Information
>6spf Chain n (length=98) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KESMKNRELKRQLTVAKYAKKRAELKAIIANPNSSAEERWNAQVALQKQP
RDASASRLRNRCRLTGRPHGFYRKFGLSRNKLREAAMRGDVPGLVKAS
Ligand information
>6spf Chain a (length=1390) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaagaguuugaucauggcucagauugaacgcuggcggcaggccuaacaca
ugcaagucgagcggaugaagggagcuugcuccuggauucagcggcagacg
ggugaguaaugccuaggaaucugccugguagugggggauaacguccggaa
acgggcgcuaauaccgcauacguccugagggagaaagugggggaucuucg
gaccucacgcuaucagaugagccuaggucggauuagcuaguugguggggu
aaaggccuaccaaggcgacgauccguaacuggucugagaggaugaucagu
cacacuggaacugagacacgguccagacuccuacgggaggcagcaguggg
gaauauuggacaaugggcgaaagccugauccagccaugccgcgugucuuu
aaguugggaggaagggcaguaaguuaauaccuugcuguuuugacguuacc
aacagaauaagcaccggcuaacuucgugccagcagccgcgguaauacgaa
gggugcaagcguuaaucggaauuacugggcguaaagcgcgcguagguggu
ucagcaaguuggaugugaaauccccgggcucaaccugggaacugcaucca
aaacuacugagcuagaguacgguagagggugguggaauuuccuggaagga
acaccaguggcgaaggcgaccaccuggacugauacugacacugaggugcg
aaagcguggggagcaaacaggauuagauacccugguaguccacgccguaa
acgaugucgacuagccguugggauccuugagaucuuaguggcgcagcuaa
cgcgauaagucgaccgccuggggaguacggccgcaagguuaaaacucaaa
ugaauugacgggggcccgcacaaugcugagaacuuuccagagauggauug
gugccuucgggaacucagacacaggugcugcauggccagcucgugucgug
agauguuggguuaagucccguaacgagcgcaaccuccuuaguuaccagca
ccucgggugggcacucuaaggagacugccggugacaaaccggaggaaggu
gucaagucaucauggcccuuacggccagggcuacacacgugcuacaaugg
ucgguacaaaggguugccaagccgcgagguggagcuaaucccauaaaacc
gaucguaguccggaucgcagucugcaacucgacugcgugaagucggaauc
gcuaguaaucgugaaucagaaugucacggugaauacguucccgggccuug
uacacaccgcccgucacaccaugggaguggguugcuccagaaguagcuag
ucuaaccgcaagggggacgguuaccacggagugauucaugacugggguga
agucguaacaagguagccguaggggaaccugcggcuggau
...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<.
<<<..<<<..<<.<<<...<..<<<..>>>..>..>.>>.>>>>>.....
.<<.......<<<<<<<..<<...<<<<<<<<<.<<.....<<<<<<...
.>>>>>>......>>.>.....<<<....>>>....<<<<<<..<<....
>>>>>>>>>>>>>>>>..>>.>>>>>>><<<....<<<...<<<<<<<..
.....>>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>
.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>..
.......<<<....<<<<....>>>>..>>>..>>.>>>>>>........
..<<<<<......<<<..<..<<........>>..>..>>>.......>>
>>>.......<<<<<((.....<<<<.....<<..))>>.......>>>>
.>>>>>..>>>>>>>>>..........<<<((.....<<<<...<<<.<<
<<<<..<<<<<<<<<<......<<<<<<.....>>>>>>....>>>>>>>
>..>>.>>>>>>...<<<<<<<....<<<<<<<.....<<<<.>>>>...
.........<<....>>.>>>>>>>...>>>.>>>>...>>>...>>>>.
...<<<<<<<...<...<<<<.........>>>>...>>>>>>>>.....
.....<<<<<<..<<<<<<<<<<<<.....>>>>>>>>>>>>...<<..)
)>>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)
))).]<<<<<.<<<<<<<.<<....<<<.........<.......>....
...<......>....>>>.........<..........<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>....................<<
.......>>..................<<<<<.....>>>>>........
.............>....................................
..................................................
..................................................
....................................>>...>>>>>>>>>
>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<....<<<<<<.<
<<<..<<....>>.>>>>>>>>>>...>>>>>>>>>>>>..>>>.>>>>.
.>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6spf Structure ofPseudomonas aeruginosaribosomes from an aminoglycoside-resistant clinical isolate.
Resolution2.89 Å
Binding residue
(original residue number in PDB)		E4 K19 K28 I31 A32 P34 Q45 V46 A47 L48 Q49 K50 Q51 P52 R53 L60 R75 R85
Binding residue
(residue number reindexed from 1)		E2 K17 K26 I29 A30 P32 Q43 V44 A45 L46 Q47 K48 Q49 P50 R51 L58 R73 R83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6spf, PDBe:6spf, PDBj:6spf
PDBsum6spf
PubMed31611393
UniProtE2RXT8

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