Structure of PDB 7xsz Chain m Binding Site BS01

Receptor Information
>7xsz Chain m (length=1187) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LQGEQYQEIIEIFGDGTDYQWTLDAEEEMEQPTSLADVFEPSELKEKMLT
DEDNVIRVTDLPERFQAYRKSIKNYKLSDVDYSNERDWIVEQLKLEKRDF
LQHLTQAHSSVAHLEEKFEASVKKIVDFIAIESFEVPFIWNHRRDYALHT
YNDDSNNTIIVKLLNEDDLWRIVQLDLDYHSIHDKKAALSSIYKQLDLDV
VDPTYEEFFGSARTLSELQDIDDYLTFNYSSQVKNLTAVMKRKYSKYAIY
DRIRQDAIYPVVQSIANISQMRENLAQSKRLHQVEDPIESPMDMIADIMS
TEKDKTTFISSEKAYQAVKQFFSEQLSYEPFIRKTIRTAFQSFGVINIEL
TERGKLQIEPESPYFDFKYAKNRPISALTATPDLYLRMIQAENDGLVNIK
VELPMLSTVVDHFYNILKSDGTSEISEKWNALRNDAWKQSLDKLIPLVQL
NVKESIRRDCERVLYFQVKNSFTKKIDQAPYQPPTYAKGTIPRVLTLSFG
EGNRGDAVLGVFMDDSGDVKSQIKFDEDFQSRDFSDSLTRYIKSNNINPD
IIGISGFNIHTKKLFDKVNELVNEERLTIEYDNSDKHLIRVIYVNDETAR
LYQHSSKSSAEYPNRPQLAKYCIGLAKYIQSPLLEYLALDESMYSLHIHK
HQNLLPREKLIDAVQTSIVDIVNLVGVDINEAVRAPYHALALPYVCGLGP
RKAAGLIQSIQRIGSNLVNRAHLITEQLTSKTVFLNMASFVYIVFDPDVE
RNPQGEMDLLDSTRIHPEDYSLARKMAADALDIEDIDDDDESAMRNAIYE
MVFPRSPPKDEDDLTFKLDELILDDYATELERKHQLKKRSTLQIIKEELQ
SRYREIRRDFHILNEAEIFQLLTRETVDSFRKGMVIPVYVRKVESSYMSV
STQSLIAGNIQRQDILEPNDRRDPREVYSVGQTVRACILDVDYYNFKCQL
SLLRQFTENQVAGLNVNRNPKFWDIESENRDRQEEIDKQREESRESRVIK
HPFFHNMKSKEAEDYLAARPVGDVVIRPSSKGSNHITISWKVAPQLYQHI
DVLEENKDDANAIGRVLLVGKYRYHDLDELLVEYVNNVANKVELMVSHDK
FMSDSLDYVKEWLERYSKANGNRSHYIFTFNRKAPGWFFLLFKLNPTSEI
KIWNVKALPDGYLLANNVYPDTNSLCNGFKTLMSSRR
Ligand information
>7xsz Chain P (length=20) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuugugcugucuucgucca
....................
Receptor-Ligand Complex Structure
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PDB7xsz Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		R775 R1173
Binding residue
(residue number reindexed from 1)		R504 R891
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003746 translation elongation factor activity
GO:0031491 nucleosome binding
GO:0042393 histone binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0006414 translational elongation
GO:0010467 gene expression
GO:0034728 nucleosome organization
GO:0140673 transcription elongation-coupled chromatin remodeling
Cellular Component
GO:0005634 nucleus
GO:0005721 pericentric heterochromatin
GO:0008023 transcription elongation factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xsz, PDBe:7xsz, PDBj:7xsz
PDBsum7xsz
PubMed35981082
UniProtC4R7H2

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