Structure of PDB 6ybs Chain m Binding Site BS01

Receptor Information
>6ybs Chain m (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPM
YVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVV
VKDYGKESQAKDVIEEYFKCKK
Ligand information
>6ybs Chain A (length=501) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auugacggaagggcaccaccaggaguggagccugcggcuuaauuugacuc
aacacgggaaaccucacccggcccggacacggacaggauugacagauuga
uagcucuuucucgauuccgugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccgauaacgaacgagacucuggcaugc
uaacuaguuacgcgacccccgagcggucggcgucccccaacuucuuagag
ggacaaguggcguucagccacccgagauugagcaauaacaggucugugau
gcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgu
gugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgu
gauggggaucggggauugcaauuauuccccaugaacgaggaauucccagu
aagugcgggucauaagcuugcguugauuaagucccugcccuuuguacaca
c
..<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<....
....>>..........<<<<<.<....<<<<<<.......<<.<<<....
....>>>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<......>>...<<<......>>>...>>.>>>....<<<...<...<
<<<..<<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..
>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>
>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<.<<<........
<.......<<<.<<<<....>>>>.>>>....>.........>>>.>>..
....<.....<<<<<..........>>>>>.....>.....>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ybs Structure of a human 48Stranslational initiation complex.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R33 G34 I35 R36 E37 K40 D57 Y61 L91 K102 V104 C106 S107
Binding residue
(residue number reindexed from 1)		R23 G24 I25 R26 E27 K30 D47 Y51 L81 K92 V94 C96 S97
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1990145 maintenance of translational fidelity
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005840 ribosome
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0032040 small-subunit processome
GO:0043231 intracellular membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6ybs, PDBe:6ybs, PDBj:6ybs
PDBsum6ybs
PubMed32883864
UniProtP25398|RS12_HUMAN Small ribosomal subunit protein eS12 (Gene Name=RPS12)

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